Zobrazeno 1 - 10 of 80 pro vyhledávání: '"L, Ruest"'
1
3D/2D Hydrogen-Bond Network Preferences for Five New Ryanoid Derivatives
Autor: M. Drouin, L. Ruest, M. Dodier
Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 54:687-693
Ryanoids are a family of natural compounds that are well known for their biological activity in plants as pesticides, and in mammalian muscle tissue as calcium permeability modulators. As part of an investigation of the structure-activity relationshi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf251b620db41ef3c9e9b942e11aca63
https://doi.org/10.1107/s0108270197016843
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3
Solid-state stereochemistry of Diels–Alder adducts between a bicyclic cyclohexadienone derivative and α-acyloxyacrylonitrile
Autor: Pierre Deslongchamps, N. Michel-Dewez, A. G. Michel, Marc Drouin, L. Ruest, G. Boulay
Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 47:764-768
C 17 H 17 NO 6 (I) cristallise dans P2 1 /a avec a=9,3791, b=14,8506, c=12,7209 A, β=110,188°, Z=4; affinement jusqu'a R=0,045. C 21 H 23 NO 8 (II) cristallise dnas P2 1 nb avec a=8,5159, b=10,3035, c=23,1263 A, Z=4; affinement jusqu'a R=0,027. C 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cb5bf11612493afc72302439d0dde4d
https://doi.org/10.1107/s0108270190006588
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4
The pharmacology of ryanodine and related compounds
Autor: J L, Sutko, J A, Airey, W, Welch, L, Ruest
Publikováno v: Pharmacological reviews. 49(1)
The goal of this review has been to describe the current state of the pharmacology of ryanodine and related compounds relative to the vertebrate RyRs. Resolution of questions concerning the molecular properties of RyR channel function and the contrib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c1cb6e21fa8ba92b8c0a81af4e34a47
https://pubmed.ncbi.nlm.nih.gov/9085309
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5
High affinity C10-Oeq ester derivatives of ryanodine. Activator-selective agonists of the sarcoplasmic reticulum calcium release channel
Autor: R A, Humerickhouse, K R, Bidasee, K, Gerzon, J T, Emmick, S, Kwon, J L, Sutko, L, Ruest, H R, Besch
Publikováno v: The Journal of biological chemistry. 269(48)
The plant alkaloids ryanodine and dehydroryanodine are specific and potent modulators of the sarcoplasmic reticulum calcium release channel. In the present study, acidic, basic, and neutral side chains esters of these diterpene compounds were prepare
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e7142f7bb6fb649a18d6554ae1c599c
https://pubmed.ncbi.nlm.nih.gov/7982934
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6
Differential activating and deactivating effects of natural ryanodine congeners on the calcium release channel of sarcoplasmic reticulum: evidence for separation of effects at functionally distinct sites
Autor: R A, Humerickhouse, H R, Besch, K, Gerzon, L, Ruest, J L, Sutko, J T, Emmick
Publikováno v: Molecular pharmacology. 44(2)
Two novel natural ryanoids from extracts of the wood of Ryania speciosa Vahl were evaluated with sarcoplasmic reticulum (SR) vesicles for their binding affinities and their activating and deactivating effects on Ca2+ release channels. The new ryanoid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45d1fd23132ce96bb4e55206d3aa0291
https://pubmed.ncbi.nlm.nih.gov/8394996
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8
Cyanoethylations and Michael additions. V. The synthesis of allylic cyclohexenols by γ-cyanoethylation of α,β-unsaturated aldehydes and ketones. Part V
Autor: Ch. R. Engel, V. S. Salvi, L. Ruest
Publikováno v: Canadian Journal of Chemistry. 48:3425-3439
It is shown that the cyanoethylation of 3β-acetoxy-21-methyl-5α-pregn-17-en-21-one results in part in the addition of acrylonitrile to the γ-position, with concomitant cyclization, and that therefore the cyclo-γ-cyanoethylations of α,β-unsatura
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05706161de70e8fbc3b3ce133da6eacf
https://doi.org/10.1139/v70-572
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9
Cyanoethylations and Michael additions. IV. The synthesis of allylic cyclohexenols by γ-cyanoethylation of α, β-unsaturated aldehydes and ketones. Part IV
Autor: Ch. R. Engel, L. Ruest
Publikováno v: Canadian Journal of Chemistry. 48:3136-3143
The cyclo-γ-cyanoethylation of 3β-acetoxy-D-homo-5α-pregn-17a-en-21-al is reported. It is shown that the orientation of the cyanoethylation of 2-cycloalkyl-substituted ethenals does not significantly depend on the ring size of the cycloalkyl subst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b96de9be1355c5e1aeefdae7c1806c0
https://doi.org/10.1139/v70-530
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10
The Cotton Effects of Conjugated Homoannular Dienes. I. The Non-generality of the Rule of Moscowitz
Autor: J. Lessard, L. Ruest, Ch. R. Engel
Publikováno v: Canadian Journal of Chemistry. 50:1433-1437
The non-generality of the diene rule of Moscowitz, relating the helicity of a non-planar conjugated homoannular diene to the sign of its Cotton effect, is discussed. We report the preparation of 3β-bromoacetoxy-16α-ethyl-162-cyano-162,21-cyclo-5α-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::050f59eba3533c81b1c717d2f3c8802c
https://doi.org/10.1139/v72-225
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