Zobrazeno 1 - 10
of 90
pro vyhledávání: '"L, Riser"'
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109864- (2024)
Summary: Hippo was first identified in a genetic screen as a protein that suppressed proliferation and cell growth. Subsequently, it was shown that hippo acted in a so-called canonical cascade to suppress Yorkie, the Drosophila equivalent of Yes-acti
Externí odkaz:
https://doaj.org/article/ed87311d106e47aba613071282f03ca0
Autor:
Andrea Resovi, Patrizia Borsotti, Tommaso Ceruti, Alice Passoni, Massimo Zucchetti, Alexander Berndt, Bruce L. Riser, Giulia Taraboletti, Dorina Belotti
Publikováno v:
Cells, Vol 9, Iss 4, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Externí odkaz:
https://doaj.org/article/814b2712dc644b48b6b7bb898871a43d
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21651840bbeef672d16c768adefd01cc
https://doi.org/10.1007/978-1-0716-2744-0_21
https://doi.org/10.1007/978-1-0716-2744-0_21
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2582
Approximately 45% of the deaths in the developed world result from conditions with a fibrotic component. Although no specific, focused anti-fibrotic therapies have been approved for clinical use, a long-standing concept is that targeting CCN proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26a241f514ec9c6f19837f11377b8090
https://pubmed.ncbi.nlm.nih.gov/36370359
https://pubmed.ncbi.nlm.nih.gov/36370359
Autor:
Alferso C Abrahams, Sayed M Habib, Amélie Dendooven, Bruce L Riser, Jan Willem van der Veer, Raechel J Toorop, Michiel G H Betjes, Marianne C Verhaar, Christopher J E Watson, Tri Q Nguyen, Walther H Boer
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112050 (2014)
IntroductionEncapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD). The pathogenesis is not exactly known and no preventive strategy or targeted medical therapy is available. CCN2 has both pro-fibrotic and
Externí odkaz:
https://doaj.org/article/fc8d2500790e4b3380c87aa87f51bc20
Autor:
Dorina Belotti, Massimo Zucchetti, Andrea Resovi, Patrizia Borsotti, Alexander Berndt, Bruce L Riser, Giulia Taraboletti, Alice Passoni, Tommaso Ceruti
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 952, p 952 (2020)
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears to be a promising therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24a5e124d7e6b60fb96aac77464450f
http://europepmc.org/articles/PMC7226963
http://europepmc.org/articles/PMC7226963
Publikováno v:
Journal of Cell Communication and Signaling. 9:327-339
The CCN family of matricellular signaling proteins is emerging as a unique common link across multiple diseases and organs related to injury and repair. They are now being shown to play a central role in regulating the pathways to the initiation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca65c2988cc81ee5fe841e9a1f06c5dd
https://doi.org/10.1007/s12079-015-0309-3
https://doi.org/10.1007/s12079-015-0309-3
Autor:
Rodrigo Bueno de Oliveira, Vanda Jorgetti, Fellype Carvalho Barreto, Sabrina Poirot, Bruce L. Riser, Ziad A. Massy, Joyce Benchitrit, Tilman B. Drüeke, Loïc Louvet, Raja Rezg
Publikováno v:
Calcified Tissue International. 97:179-192
Chronic kidney disease (CKD) is generally associated with disturbances of mineral and bone metabolism. They contribute to the development of vascular calcification (VC), a strong, independent predictor of cardiovascular risk. Pyrophosphate (PPi), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53f74645511776b61381cda2268af33
https://doi.org/10.1007/s00223-015-0020-7
https://doi.org/10.1007/s00223-015-0020-7
Autor:
Bruce L. Riser, Sarah C. Riser, Bernard Perbal, Ernest J. Sukowski, Feridoon Najmabadi, Melisa L. Riser, Herman Yeger, Darryl R. Peterson, Jo Ann Rambow
Publikováno v:
Journal of Cell Communication and Signaling. 4:39-50
Prior work in the CCN field, including our own, suggested to us that there might be co-regulatory activity and function as part of the actions of this family of cysteine rich cytokines. CCN2 is now regarded as a major pro-fibrotic molecule acting bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c47ae112b5eb5f8fcbd84b56641622
https://doi.org/10.1007/s12079-010-0085-z
https://doi.org/10.1007/s12079-010-0085-z
Autor:
Kendra Garchow, Bruce L. Riser, Ernest J. Sukowski, Feridoon Najmabadi, Jeffrey L. Barnes, Darryl R. Peterson
Publikováno v:
The American Journal of Pathology. 184:2908-2921
Fibrosis is at the core of the high morbidity and mortality rates associated with the complications of diabetes and obesity, including diabetic nephropathy (DN), without any US Food and Drug Administration–approved drugs with this specific target.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2e386b2f20a41e93fe56dd019a543b
https://doi.org/10.1016/j.ajpath.2014.07.009
https://doi.org/10.1016/j.ajpath.2014.07.009