Zobrazeno 1 - 10
of 615
pro vyhledávání: '"L, REINER"'
Autor:
Ning Wang, Sean Cho, Dana Piovesan, Cesar Meleza, Patrick G Schweickert, Gabrielle L Reiner, Casey G Mitchell, Juan Jose Fung, Jeremy Fournier, Matthew J Walters, Kelsey E Sivick Gauthier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2c126220155e4a05b4e6fa603aec1da7
Autor:
Peter H. Wang, Robert S. Washburn, Dylan L. Mariuzza, Wen-Hsuan W. Lin, Amanda L. Gill, Rafi Ahmed, Steven L. Reiner
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113155- (2023)
Summary: The ability of activated progenitor T cells to self-renew while producing differentiated effector cell descendants may underlie immunological memory and persistent responses to ongoing infection. The nature of stem-like T cells responding to
Externí odkaz:
https://doaj.org/article/e72a4595935b4b48969acd8c20e34a7b
Autor:
Philip Tanabe, Peter B. Key, Katy W. Chung, Emily C. Pisarski, Jessica L. Reiner, Alix E. Rodowa, Jason T. Magnuson, Marie E. DeLorenzo
Publikováno v:
Toxics, Vol 12, Iss 1, p 91 (2024)
Per- and polyfluoroalkyl substances (PFAS) are ubiquitous and persistent environmental contaminants originating from many everyday products. Perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are two PFAS that are commonly found a
Externí odkaz:
https://doaj.org/article/69c894e42135415692c933df0799f313
Autor:
Jacqueline Bangma, T.C. Guillette, Paige A. Bommarito, Carla Ng, Jessica L. Reiner, Andrew B. Lindstrom, Mark J. Strynar
Publikováno v:
Environment International, Vol 159, Iss , Pp 107037- (2022)
Per- and polyfluoroalkyl substances (PFAS) accumulation and elimination in both wildlife and humans is largely attributed to PFAS interactions with proteins, including but not limited to organic anion transporters (OATs), fatty acid binding proteins
Externí odkaz:
https://doaj.org/article/8a453aa77fe846a9897ba6e3e0ea774b
Publikováno v:
Cancers, Vol 14, Iss 23, p 5940 (2022)
Gastric adenocarcinoma is by far the most common form of gastric cancer (GC) and is a highly lethal form of cancer arising from the gastric epithelium. GC is an important area of focus of the medical community, given its often late-stage of diagnosis
Externí odkaz:
https://doaj.org/article/03f3708daee74c859011de5fcc06dc91
Publikováno v:
Fire, Vol 5, Iss 5, p 137 (2022)
Estimates of burn severity and forest change following wildfire are used to determine changes in forest cover, fuels, carbon stocks, soils, wildlife habitat, and to evaluate fuel and fire management strategies and effectiveness. However, current remo
Externí odkaz:
https://doaj.org/article/1ee6922d801740bfb555f989ff7e7220
Autor:
Rohan Maniar, Peter H. Wang, Robert S. Washburn, Radomir Kratchmarov, Shana M. Coley, Anjali Saqi, Samuel S. Pan, Jianhua Hu, Catherine A. Shu, Naiyer A. Rizvi, Brian S. Henick, Steven L. Reiner
Publikováno v:
Cancer Immunology Research. 11:164-170
Treatment with immune checkpoint blockade (ICB) often fails to elicit durable antitumor immunity. Recent studies suggest that ICB does not restore potency to terminally dysfunctional T cells, but instead drives proliferation and differentiation of se
Publikováno v:
Blood Advances, Vol 2, Iss 14, Pp 1685-1690 (2018)
Abstract: Expression of the transcription factor T-cell factor 1 (TCF1) identifies antigen-experienced murine CD8+ T cells that retain potential for lymphoid recirculation and the ability to self-renew while producing more differentiated effector cel
Externí odkaz:
https://doaj.org/article/70f61d26b192483f8eb9ca3111db9cb8
Autor:
Yen-Hua Chen, Radomir Kratchmarov, Wen-Hsuan W. Lin, Nyanza J. Rothman, Bonnie Yen, William C. Adams, Simone A. Nish, Jeffrey C. Rathmell, Steven L. Reiner
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 860-868 (2018)
Unequal transmission of nutritive signaling during cell division establishes fate disparity between sibling lymphocytes, but how asymmetric signaling becomes organized is not understood. We show that receptor-associated class I phosphatidylinositol 3
Externí odkaz:
https://doaj.org/article/7461fd78f1ed4b0c926b4242d57a9d12
Autor:
Peter H. Wang, Robert Washburn, Rohan Maniar, Michael Mu, Olivia Ringham, Radomir Kratchmarov, Brian S. Henick, Steven L. Reiner
Publikováno v:
The Journal of Immunology. 209:660-664
Immune checkpoint blockade is limited by resistance to treatment, with many patients not achieving durable antitumor responses. Self-renewing (T cell factor 1+ [TCF1+]) CD8+ T cells have recently been implicated in efficacy of anti–programmed cell