Zobrazeno 1 - 10
of 1 554
pro vyhledávání: '"L, Poston"'
Autor:
Tien Dam, Gennaro Pagano, Michael C. Brumm, Caroline Gochanour, Kathleen L. Poston, Daniel Weintraub, Lana M. Chahine, Christopher Coffey, Caroline M. Tanner, Catherine M. Kopil, Yuge Xiao, Sohini Chowdhury, Luis Concha-Marambio, Peter DiBiaso, Tatiana Foroud, Mark Frasier, Danna Jennings, Karl Kieburtz, Kalpana Merchant, Brit Mollenhauer, Thomas J. Montine, Kelly Nudelman, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Andrew Siderowf, Billy Dunn, Tanya Simuni, Kenneth Marek, the Parkinson’s Progression Markers Initiative
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The Neuronal alpha-Synuclein Disease (NSD) biological definition and Integrated Staging System (NSD-ISS) provide a research framework to identify individuals with Lewy body pathology and stage them based on underlying biology and increasing
Externí odkaz:
https://doaj.org/article/bcf123a33df949f9999736ef3c3dd94e
Autor:
Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met
Externí odkaz:
https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9
Autor:
Thanaphong Phongpreecha, Kavita Mathi, Brenna Cholerton, Eddie J. Fox, Natalia Sigal, Camilo Espinosa, Momsen Reincke, Philip Chung, Ling-Jen Hwang, Chandresh R. Gajera, Eloise Berson, Amalia Perna, Feng Xie, Chi-Hung Shu, Debapriya Hazra, Divya Channappa, Jeffrey E. Dunn, Lucas B. Kipp, Kathleen L. Poston, Kathleen S. Montine, Holden T. Maecker, Nima Aghaeepour, Thomas J. Montine
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Multiple lines of evidence support peripheral organs in the initiation or progression of Lewy body disease (LBD), a spectrum of neurodegenerative diagnoses that include Parkinson’s Disease (PD) without or with dementia (PDD) and
Externí odkaz:
https://doaj.org/article/8a91d0cff3514c658c48b733f4355809
Autor:
Melanie J. Plastini, Carla Abdelnour, Christina B. Young, Edward N. Wilson, Marian Shahid‐Besanti, Jennifer Lamoureux, Katrin I. Andreasson, Geoffrey A. Kerchner, Thomas J. Montine, Victor W. Henderson, Kathleen L. Poston
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 5, Pp 1197-1210 (2024)
Abstract Objective More than half of neurodegenerative disease patients have multiple pathologies at autopsy; however, most receive one diagnosis during life. We used the α‐synuclein seed amplification assay (αSyn‐SAA) and CSF biomarkers for am
Externí odkaz:
https://doaj.org/article/340d601fd43e42beb69b9417cf089816
Autor:
Joseph R. Winer, Renske Lok, Lara Weed, Zihuai He, Kathleen L. Poston, Elizabeth C. Mormino, Jamie M. Zeitzer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Sleep-wake regulating circuits are affected during prodromal stages in the pathological progression of both Alzheimer’s disease (AD) and Parkinson’s disease (PD), and this disturbance can be measured passively using wearable d
Externí odkaz:
https://doaj.org/article/ae60cc6c308a402dba4f647e0b9b77d7
Autor:
Thanaphong Phongpreecha, Dana Godrich, Eloise Berson, Camilo Espinosa, Yeasul Kim, Brenna Cholerton, Alan L. Chang, Samson Mataraso, Syed A. Bukhari, Amalia Perna, Koya Yakabi, Kathleen S. Montine, Kathleen L. Poston, Elizabeth Mormino, Lon White, Gary Beecham, Nima Aghaeepour, Thomas J. Montine
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background We have proposed that cognitive resilience (CR) counteracts brain damage from Alzheimer’s disease (AD) or AD-related dementias such that older individuals who harbor neurodegenerative disease burden sufficient to cause dementia
Externí odkaz:
https://doaj.org/article/3e8f258973304acfa004fd1140c9ced5
Autor:
Carla Abdelnour, Maria Camila Gonzalez, Lucy L. Gibson, Kathleen L. Poston, Clive G. Ballard, Jeffrey L. Cummings, Dag Aarsland
Publikováno v:
Neurology and Therapy, Vol 12, Iss 3, Pp 727-749 (2023)
Abstract Introduction Reviews of randomized clinical trials (RCTs) in dementia with Lewy bodies (DLB) are essential for informing ongoing research efforts of symptomatic therapies and potentially disease-modifying therapies (DMTs). Methods We perform
Externí odkaz:
https://doaj.org/article/1098fd9019dd4ba8a04039d27687ce28
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION The National Alzheimer's Coordinating Center (NACC) Uniform Data Set (UDS) neuropsychological battery is being used to track cognition in participants across the country, but it is unknown if scores obtained through remote admin
Externí odkaz:
https://doaj.org/article/9fda87c2dea14aa7b6df9e7727f18d29
Autor:
Joseph R. Winer, Renske Lok, Adrian Ekelmans, Flavia Bueno, Kathleen L. Poston, Jamie M. Zeitzer, Emmanuel H. During
Publikováno v:
Frontiers in Sleep, Vol 2 (2023)
IntroductionIsolated REM sleep behavior disorder (iRBD), the loss of motor inhibition during REM sleep, is a symptom of prodromal Lewy body disease, with over 80% of iRBD patients progressing to Parkinson's disease or dementia with Lewy bodies. Disru
Externí odkaz:
https://doaj.org/article/b093e9012a8a4f6495e53cdd807cc5f2
Autor:
Christina B. Young, Emily Johns, Gabriel Kennedy, Michael E. Belloy, Philip S. Insel, Michael D. Greicius, Reisa A. Sperling, Keith A. Johnson, Kathleen L. Poston, Elizabeth C. Mormino, for the Alzheimer’s Disease Neuroimaging Initiative, the A4 Study Team
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background APOE variants are strongly associated with abnormal amyloid aggregation and additional direct effects of APOE on tau aggregation are reported in animal and human cell models. The degree to which these effects are present in humans
Externí odkaz:
https://doaj.org/article/3bee54045fa448f4900aab27548666cc