Zobrazeno 1 - 10
of 341
pro vyhledávání: '"L, Pokorny"'
Autor:
John R. Ohlfest, William F. Elmquist, Jann N. Sarkaria, Jenny L. Pokorny, Karen S. SantaCruz, Stacy A. Decker, Charlie Seiler, Randy Donelson, Jose L. Gallardo, David M. Zellmer, Rajendar K. Mittapalli, Sagar Agarwal
PDF file, 71K, Pharmacokinetic Parameters in WT and TKO Mice after Oral Dosing with 15 mg/kg Dasatinib (Data presented as Mean � S.E. of Estimate).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c79962d24bcc721f0ebffc2032e87f
https://doi.org/10.1158/1535-7163.22496526.v1
https://doi.org/10.1158/1535-7163.22496526.v1
Autor:
John R. Ohlfest, William F. Elmquist, Jann N. Sarkaria, Jenny L. Pokorny, Karen S. SantaCruz, Stacy A. Decker, Charlie Seiler, Randy Donelson, Jose L. Gallardo, David M. Zellmer, Rajendar K. Mittapalli, Sagar Agarwal
The importance of the blood–brain barrier in preventing effective pharmacotherapy of glioblastoma has been controversial. The controversy stems from the fact that vascular endothelial cell tight junctions are disrupted in the tumor, allowing some s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e61c6a68558105a5efdbf68a86fd5c9
https://doi.org/10.1158/1535-7163.c.6535308
https://doi.org/10.1158/1535-7163.c.6535308
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 55K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc838fa47a9d23267b37a858ed4d3f8
https://doi.org/10.1158/1078-0432.22447710
https://doi.org/10.1158/1078-0432.22447710
Autor:
Jann N. Sarkaria, Nathalie Y.R. Agar, William F. Elmquist, Stuart D. Shumway, Bennett Ma, Vincenzo Pucci, Jeanette E. Eckel-Passow, Paul A. Decker, Zhenkun Lou, Debra L. Evans, Mark A. Schroeder, Brett L. Carlson, Katrina K. Bakken, Dustin Mueller, Dennis O. Iyekegbe, Shiv K. Gupta, David Calligaris, Jenny L. Pokorny
Supplementary Figure S5. MALDI-TOF MS analyses of MK-1775 (m/z 501.2)in brain and flank GBM22 tumor samples after treatment with placebo or MK-1775
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353f8a860b6932933b90938e0a9d0c07
https://doi.org/10.1158/1078-0432.22454537
https://doi.org/10.1158/1078-0432.22454537
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 77K, Cell viability following treatment with GNE-317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b14e8b2c62065f86e47c21ee5d4697a
https://doi.org/10.1158/1078-0432.22447713.v1
https://doi.org/10.1158/1078-0432.22447713.v1
Autor:
Jann N. Sarkaria, Nathalie Y.R. Agar, William F. Elmquist, Stuart D. Shumway, Bennett Ma, Vincenzo Pucci, Jeanette E. Eckel-Passow, Paul A. Decker, Zhenkun Lou, Debra L. Evans, Mark A. Schroeder, Brett L. Carlson, Katrina K. Bakken, Dustin Mueller, Dennis O. Iyekegbe, Shiv K. Gupta, David Calligaris, Jenny L. Pokorny
Supplementary Methods and Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd5b3cca6382f37122b6f4223c2f884
https://doi.org/10.1158/1078-0432.22454534
https://doi.org/10.1158/1078-0432.22454534
Autor:
Jann N. Sarkaria, Raul A. Urrutia, Shiv K. Gupta, Gwen A. Lomberk, Wenting Wu, Paul A. Decker, Ling Cen, Jenny L. Pokorny, Mark A. Schroeder, Brett L. Carlson, Ann C. Mladek, Gaspar J. Kitange
PDF file - 7K, The summary of the TMZ response: Parental vs TMZ resistant xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172784930a71d2c585d86499332ca6ed
https://doi.org/10.1158/1078-0432.22445216
https://doi.org/10.1158/1078-0432.22445216
Autor:
Jann N. Sarkaria, Nathalie Y.R. Agar, William F. Elmquist, Stuart D. Shumway, Bennett Ma, Vincenzo Pucci, Jeanette E. Eckel-Passow, Paul A. Decker, Zhenkun Lou, Debra L. Evans, Mark A. Schroeder, Brett L. Carlson, Katrina K. Bakken, Dustin Mueller, Dennis O. Iyekegbe, Shiv K. Gupta, David Calligaris, Jenny L. Pokorny
Purpose: Wee1 regulates key DNA damage checkpoints, and in this study, the efficacy of the Wee1 inhibitor MK-1775 was evaluated in glioblastoma multiforme (GBM) xenograft models alone and in combination with radiation and/or temozolomide.Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e76df6db652fd16b0b9ac0d4b706f5b
https://doi.org/10.1158/1078-0432.c.6522779
https://doi.org/10.1158/1078-0432.c.6522779
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 60K, Plasma Concentrations, Brain Concentrations and Brain-to-Plasma Ratio Measured at the End of Study (42 days) 2 hours Following the Last Daily PO Administration of GNE-317 (40 mg/kg), GDC-0941 (250 mg/kg) or GDC-0980 (10 mg/kg) to GS2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1649707918904ad8cbd83771a80366bc
https://doi.org/10.1158/1078-0432.22447701
https://doi.org/10.1158/1078-0432.22447701