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Akademický článek

Stable representation of sounds in the posterior striatum during flexible auditory decisions

Autor: Lan Guo, William I. Walker, Nicholas D. Ponvert, Phoebe L. Penix, Santiago Jaramillo

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)

Striatum mediates goal-oriented behaviors and habitual actions. This study shows that auditory information is represented by neuronal activity of the posterior tail of the dorsal striatum in mice, and that this brain region mediates rodent’s flexib

Externí odkaz: https://doaj.org/article/0cec892b19264283a2c4590c2174d43b

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Stable representation of sounds in the posterior striatum during flexible auditory decisions

Autor: Santiago Jaramillo, Nicholas D. Ponvert, William I. Walker, Lan Guo, Phoebe L. Penix

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications

The neuronal pathways that link sounds to rewarded actions remain elusive. For instance, it is unclear whether neurons in the posterior tail of the dorsal striatum (which receive direct input from the auditory system) mediate action selection, as oth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1560aeb0c9e76c6fcf9ae72910213d0
https://doaj.org/article/0cec892b19264283a2c4590c2174d43b

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Hypertension and cognitive performance in African Americans with Alzheimer disease

Autor: John Hanfelt, Felicia C. Goldstein, L. J. Freedman, A. V. Ashley, J. J. Lah, Allan I. Levey, L. Penix

Publikováno v: Neurology. 64:899-901

The authors examined the relationship between hypertension and cognitive performance in 34 African-American patients with probable Alzheimer disease. Multiple regression analyses indicated that hypertension was associated with poorer overall performa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6678480c74f8786678abe27d07399496
https://doi.org/10.1212/01.wnl.0000152888.26576.37

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Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene

Autor: H A Young, P Ghosh, J Ye, J Lederer, A Lichtman, J R Gerard, L Penix, C B Wilson, A J Melvin, M E McGurn

Publikováno v: The Journal of Immunology. 153:3603-3610

Th1 and Th2 CD4+ T cell clones have been defined by their ability to produce different lymphokines. However, the processes by which CD4+ T cells differentially regulate lymphokine gene expression have not been well defined. In this report, we demonst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36fa38ff1fbdc72d11a3e49d35c13dae
https://doi.org/10.4049/jimmunol.153.8.3603

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Apolipoprotein E and age at onset of Alzheimer's disease in African American patients

Autor: Marla Gearing, L. J. Freedman, L. Penix, Allan I. Levey, A. V. Ashley, Felicia C. Goldstein, John Hanfelt

Publikováno v: Neurology. 57:1923-1925

The authors examined whether the APOE-epsilon4 allele is associated with an earlier age at onset of AD in 71 African American patients with probable AD. The authors found a linear dose effect in which each copy of the epsilon4 allele was associated w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d97c157ef16d853ade08c2a913250a
https://doi.org/10.1212/wnl.57.10.1923

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Seizure-induced hippocampal damage and chronic epilepsy: a hebbian theory of epileptogenesis

Autor: C G, Wasterlain, A M, Mazarati, Y, Shirasaka, K W, Thompson, L, Penix, H, Liu, H, Katsumori

Publikováno v: Advances in neurology. 79

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be16c286007b9eac3b6f381d4594ed1e
https://pubmed.ncbi.nlm.nih.gov/10514867

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Regulation of the activity of IFN-gamma promoter elements during Th cell differentiation

Autor: F, Zhang, D Z, Wang, M, Boothby, L, Penix, R A, Flavell, T M, Aune

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(11)

Before they can deliver their effector functions, CD4+ Th cells must differentiate into Th1 or Th2 subsets. We have prepared reporter transgenic mice that express the luciferase gene under the control of proximal (prox.IFN-gamma) and distal (dist.IFN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::31cb7e4a57acd65cb04b16a2666c8e0a
https://pubmed.ncbi.nlm.nih.gov/9834094

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Felbamate block of the N-methyl-D-aspartate receptor

Autor: S, Subramaniam, J M, Rho, L, Penix, S D, Donevan, R P, Fielding, M A, Rogawski

Publikováno v: The Journal of pharmacology and experimental therapeutics. 273(2)

The anticonvulsant felbamate may act as an N-methyl-D-aspartate (NMDA) receptor antagonist, but the mechanism of block has not been fully characterized. We sought to identify the sites at which felbamate exerts its NMDA receptor blocking action using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dc76438e54cd0c11cc92c2b2225c536
https://pubmed.ncbi.nlm.nih.gov/7752093

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