Zobrazeno 1 - 10
of 74
pro vyhledávání: '"L, Passaglia"'
Autor:
Mustafa M. Siddiq, Nicholas P. Johnson, Yana Zorina, Arjun Singh Yadaw, Carlos A. Toro, Jens Hansen, Vera Rabinovich, Sarah M. Gregorich, Yuguang Xiong, Rosa E. Tolentino, Sari S. Hannila, Ehud Kaplan, Robert D. Blitzer, Marie T. Filbin, Christopher P. Cardozo, Christopher L. Passaglia, Ravi Iyengar
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
There are no known drugs or drug combinations that promote substantial central nervous system axonal regeneration after injury. We used systems pharmacology approaches to model pathways underlying axonal growth and identify a four-drug combination th
Externí odkaz:
https://doaj.org/article/bc2b4a9dfdb640d18ca703e4fcaa209f
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294607 (2023)
Aqueous humor dynamics are commonly assessed by infusing fluid into the eye and measuring intraocular pressure (IOP). From the pressure-flow relationship, conventional outflow facility is estimated to study glaucomatous processes that lower facility
Externí odkaz:
https://doaj.org/article/29a3efd239ec491a85c88852605f14a2
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280332 (2023)
Intraocular pressure (IOP) is heavily influenced by the resistance of trabecular outflow pathways through which most of the aqueous humor produced by the eye continuously drains. The standard method of quantifying outflow resistance and other aspects
Externí odkaz:
https://doaj.org/article/8a1bf79745394125a215189d4891d252
Autor:
Dawin Khiev, Zeinab A. Mohamed, Riddhi Vichare, Ryan Paulson, Sofia Bhatia, Subhra Mohapatra, Glenn P. Lobo, Mallika Valapala, Nagaraj Kerur, Christopher L. Passaglia, Shyam S. Mohapatra, Manas R. Biswal
Publikováno v:
Nanomaterials, Vol 11, Iss 1, p 173 (2021)
Ocular diseases can deteriorate vision to the point of blindness and thus can have a major impact on the daily life of an individual. Conventional therapies are unable to provide absolute therapy for all ocular diseases due to the several limitations
Externí odkaz:
https://doaj.org/article/3b2ddf5c0866428e8523d9e9697c2a52
Publikováno v:
Neuroscience
Rats are a popular animal model for vision research and for investigating disorders of the visual system. The study aimed to quantify the spatiotemporal contrast sensitivity function (CSF) of healthy adult Brown-Norway rats under scotopic and photopi
Publikováno v:
The Journal of Physiology. 598:403-413
Key points An elevation in intracranial pressure (ICP) lowers conventional outflow facility (increases aqueous outflow resistance) of rat eyes. The reduction in outflow facility correlates with an increase in intraocular pressure (IOP). The effect of
Autor:
Cesar Hernandez-Isidro, Mitchell Harrah, Abdul Mohaimen Safi, Stephen Cini, Ashwin B. Parthasarathy, Sadhu Moka, Christopher L. Passaglia
Publikováno v:
Biophotonics Congress 2021.
This paper demonstrates a novel approach for fast, single-shot Multi-Exposure Speckle Imaging of blood flow with a simplified imaging setup. Our method can transform existing single-exposure speckle images to quantitative flow images.
Autor:
Zeinab A. Mohamed, Christopher L. Passaglia, Glenn P. Lobo, Riddhi Vichare, Ryan J Paulson, Shyam S. Mohapatra, Nagaraj Kerur, Subhra Mohapatra, Sofia Bhatia, Dawin Khiev, Manas R. Biswal, Mallika Valapala
Publikováno v:
Nanomaterials
Nanomaterials, Vol 11, Iss 173, p 173 (2021)
Nanomaterials, Vol 11, Iss 173, p 173 (2021)
Ocular diseases can deteriorate vision to the point of blindness and thus can have a major impact on the daily life of an individual. Conventional therapies are unable to provide absolute therapy for all ocular diseases due to the several limitations
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Glaucoma-like neuropathies can be experimentally induced by disturbing aqueous outflow from the eye, resulting in intraocular pressure (IOP) changes that are variable in magnitude and time course and permanent in duration. This study introduces a nov
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