Zobrazeno 1 - 10
of 1 267
pro vyhledávání: '"L, Oakes"'
Autor:
Arik Shams, Sean A. Higgins, Christof Fellmann, Thomas G. Laughlin, Benjamin L. Oakes, Rachel Lew, Shin Kim, Maria Lukarska, Madeline Arnold, Brett T. Staahl, Jennifer A. Doudna, David F. Savage
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Proteins evolve through the modular rearrangement of domains. Here the authors introduce MISER, a minimization by iterative size-exclusion and recombination method to make all possible deletions of a protein, uncovering functions for Cas9 domains inv
Externí odkaz:
https://doaj.org/article/f92b1a4bf0574fe9b95344d8bcec8e40
Named a 2013 Doody's Core Title!'I would recommend this great little book for nurses who wish to carry a book with them in their clinical practice. Itís a great addition to the growing list of books addressing pain in pediatrics.'--Pediatric Pain Le
Autor:
R. L. Oakes, J. A. Sessa
Publikováno v:
Biogeosciences, Vol 17, Pp 1975-1990 (2020)
Pteropods have been nicknamed the “canary in the coal mine” for ocean acidification because they are predicted to be among the first organisms to be affected by changing ocean chemistry. This is due to their fragile, aragonitic shells and high ab
Externí odkaz:
https://doaj.org/article/90afc52854f043b09f7a673b4bc25b85
Autor:
Kale Kundert, James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin M. Heineike, Christina M. Fitzsimmons, Benjamin L. Oakes, Jiuxin Qu, Neha Prasad, Oren S. Rosenberg, David F. Savage, Hana El-Samad, Jennifer A. Doudna, Tanja Kortemme
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Control of CRISPR-Cas9 activity allows for fine-tuning of editing and gene expression. Here the authors use gRNAs modified with RNA aptamers to enable small molecule control in bacterial systems.
Externí odkaz:
https://doaj.org/article/75a198d8f2ba47a985055e98863b4ffd
Publikováno v:
Frontiers in Marine Science, Vol 7 (2021)
Pteropods have been hailed as the “canary in the coal mine” for ocean acidification, however, questions remain about their life history, habitat, and the environmental parameters that the isotopic composition of their shells reflect. In order to
Externí odkaz:
https://doaj.org/article/12a222e8a58245e1bc2afc35e00724d5
Autor:
Cindy M. Yamamoto, Melanie L. Oakes, Taku Murakami, Michael G. Muto, Ross S. Berkowitz, Shu-Wing Ng
Publikováno v:
Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Background Extracellular vesicles (EVs) are considered as a new class of resources for potential biomarkers. We analyzed expression of specific mRNA and miRNA in EVs derived from ovarian cancer ascites and the ideal controls, peritoneal flui
Externí odkaz:
https://doaj.org/article/f2694fda46c9428198be1af1721a81d8
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Sea butterflies, or pteropods, are often presented as being at threat from ocean acidification on account of their fragile shells being susceptible to dissolution. Here the authors show that pteropods are able to perform extensive repair to damaged s
Externí odkaz:
https://doaj.org/article/b1a8a4a0076a4c05a0ea9470e5adc3bc
Autor:
Guangrong Qin, Jin Dai, Sylvia Chien, Timothy J. Martins, Brenda Loera, Quy Nguyen, Melanie L. Oakes, Bahar Tercan, Boris Aguilar, Lauren Hagen, Jeannine McCune, Richard Gelinas, Raymond J. Monnat, Ilya Shmulevich, Pamela S. Becker
Acute myeloid leukemia (AML) is an aggressive malignancy of myeloid progenitor cells characterized by successive acquisition of genetic alterations. This inherent heterogeneity poses challenges in the development of precise and effective therapies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8319f859d807a96395214f8382eacf71
https://doi.org/10.1101/2023.05.24.541944
https://doi.org/10.1101/2023.05.24.541944
Publikováno v:
ICES Journal of Marine Science.
The pteropod Limacina helicina has become an important bioindicator species for the negative impacts of ocean acidification (OA) on marine ecosystems. However, pteropods diversified during earlier high CO2 periods in Earth history and currently inhab
Autor:
Benjamin L. Oakes, Danny F. Xia, Elizabeth F. Rowland, Denise J. Xu, Irina Ankoudinova, Jennifer S. Borchardt, Lei Zhang, Patrick Li, Jeffrey C. Miller, Edward J. Rebar, Marcus B. Noyes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zinc finger nucleases have an established role in genome editing. Here, the authors report a strategy for identifying zinc finger nucleases that discriminate between desired targets and provide genome-wide specificity.
Externí odkaz:
https://doaj.org/article/e66bba0eeef149b0809ce032052bdf58