Zobrazeno 1 - 10
of 60
pro vyhledávání: '"L, Nannizzi"'
Publikováno v:
Blood. 82:2125-2136
The recently cloned functional thrombin receptor is thought to be activated by thrombin cleavage of the bond between R41 and S42, followed by the insertion of the new N-terminal region (“tethered ligand”) into an unknown site in the receptor. Ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d17f300c2a0e337526ff1bbb580a2eb
https://doi.org/10.1182/blood.v82.7.2125.bloodjournal8272125
https://doi.org/10.1182/blood.v82.7.2125.bloodjournal8272125
Autor:
Israel F. Charo, Willy Teng, M. A. Naughton, Robert M. Scarborough, L. Nannizzi, David R. Phillips, A.M. Campbell, A. Arfsten, J. W. Rose
Publikováno v:
Journal of Biological Chemistry. 268:1066-1073
Members of the snake venon-derived, "disintegrin" peptide family containing the Arg-Gly-Asp (RGD) amino acid sequence are among the most potent inhibitors of the binding of adhesive proteins to platelet glycoprotein (GP) IIb-IIIa. However, GPIIb-IIIa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91081ae25e97036bb9d3bbdbc60d0fa7
https://doi.org/10.1016/s0021-9258(18)54042-4
https://doi.org/10.1016/s0021-9258(18)54042-4
Autor:
Israel F. Charo, A.M. Campbell, L. Nannizzi, David R. Phillips, A. Arfsten, M. A. Naughton, J. W. Rose, Robert M. Scarborough
Publikováno v:
Journal of Biological Chemistry. 268:1058-1065
A new series of homologous disintegrins was isolated from the venoms of new world pit viper genus Bothrops, Crotalus, and Lachesis. The relative activities of each disintegrin in blocking adhesive protein binding activities of GPIIb-IIIa, alpha v bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c70a3c6a5d881149761943d93b5552
https://doi.org/10.1016/s0021-9258(18)54041-2
https://doi.org/10.1016/s0021-9258(18)54041-2
Autor:
M.A. Hsu, L. Nannizzi, David R. Phillips, V.A. Fried, A.M. Campbell, Israel F. Charo, J.W. Rose, Robert M. Scarborough
Publikováno v:
Journal of Biological Chemistry. 266:9359-9362
Sixty-two snake venoms were screened to identify those which specifically inhibit the adhesive protein binding function of the glycoprotein (GP) IIb-IIIa complex, the receptor-mediating platelet aggregation. Although 52 of these venoms inhibited GPII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a814ae3beecc5c7ecdf342bd74238efb
https://doi.org/10.1016/s0021-9258(18)92826-7
https://doi.org/10.1016/s0021-9258(18)92826-7
Publikováno v:
Journal of Biological Chemistry. 266:1415-1421
The glycoprotein IIb-IIIa complex (GP IIb-IIIa) mediates platelet aggregation and is a member of the cytoadhesin family of receptors that bind adhesive proteins such as fibrinogen, fibronectin, and von Willebrand factor. Despite the wide range of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0ce4df2197d5396678cd463779a9b1
https://doi.org/10.1016/s0021-9258(18)52310-3
https://doi.org/10.1016/s0021-9258(18)52310-3
Publikováno v:
The Journal of Cell Biology
The vitronectin receptor (alpha v beta 3) is a member of the integrin superfamily of adhesive protein receptors that mediate a wide spectrum of adhesive cellular interactions, including attachment to vitronectin, von Willebrand factor, fibrinogen, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e037c31e0bad76ce9bc160a5e5677fb5
https://doi.org/10.1083/jcb.111.6.2795
https://doi.org/10.1083/jcb.111.6.2795
Publikováno v:
Blood. 75:2363-2368
The glycoprotein IIb-IIIa complex (GP IIb-IIIa) is a multifunctional transmembrane protein on platelets. Its most completely described function is as a fibrinogen receptor that mediates platelet aggregation, but it is also involved in clot retraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d7cb800560dae649f5bf38235bc4e99
https://doi.org/10.1182/blood.v75.12.2363.bloodjournal75122363
https://doi.org/10.1182/blood.v75.12.2363.bloodjournal75122363
Publikováno v:
Thrombosis and haemostasis. 82(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::038f47aad3eba26ce285a00ece8c10e3
https://pubmed.ncbi.nlm.nih.gov/10605723
https://pubmed.ncbi.nlm.nih.gov/10605723
Publikováno v:
The Journal of biological chemistry. 271(18)
alpha IIb beta 3-(GP IIb IIIa) is the most abundant integrin expressed on platelets and plays a critical role in platelet aggregation and normal hemostasis. In response to platelet stimulation by agonists such as thrombin, alpha IIb beta 3 becomes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fab037882d407f492cdc1cde068cbe5d
https://pubmed.ncbi.nlm.nih.gov/8631894
https://pubmed.ncbi.nlm.nih.gov/8631894
Autor:
R M, Scarborough, M A, Naughton, W, Teng, J W, Rose, D R, Phillips, L, Nannizzi, A, Arfsten, A M, Campbell, I F, Charo
Publikováno v:
The Journal of biological chemistry. 268(2)
Members of the snake venon-derived, "disintegrin" peptide family containing the Arg-Gly-Asp (RGD) amino acid sequence are among the most potent inhibitors of the binding of adhesive proteins to platelet glycoprotein (GP) IIb-IIIa. However, GPIIb-IIIa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::679eb6de36ac165daacac3f65ae2fd20
https://pubmed.ncbi.nlm.nih.gov/8419315
https://pubmed.ncbi.nlm.nih.gov/8419315