Zobrazeno 1 - 10
of 56
pro vyhledávání: '"L, Micco"'
Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion
Autor:
Patrick T F Kennedy, Laura J. Pallett, L. Micco, Dimitra Peppa, Anna Schurich, David H. Adams, Nicholas Easom, G. Nebbia, H Singh, Upkar S. Gill, Mala K. Maini, Gary M. Reynolds
Publikováno v:
The Journal of Experimental Medicine
Hepatic NK cells eliminate HBV-specific T cells dependent on TRAIL and TRAIL-R2 interactions to limit antiviral immunity in chronic infection.
Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are profou
Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are profou
Autor:
Annagiulia Gramenzi, L. Micco, Silvia Galli, Pietro Andreone, Elisabetta Loggi, Mauro Bernardi, Sirio Fiorino, Stefano Gitto, Claudio Galli, Carmela Cursaro, Giuliano Furlini
Publikováno v:
Journal of Viral Hepatitis. 18:e468-e474
Serum hepatitis B virus surface antigen (HBsAg) levels have been suggested to predict interferon response in chronic hepatitis B. A few data are available on the role of HBsAg measurement in nucleos(t)ide analogues (NA) treatment. We retrospectively
Autor:
Upkar S. Gill, Damien Tan, Kamini Kunasegaran, Laura Rivino, Patrick T F Kennedy, Nina Le Bert, Mala K. Maini, Antonio Bertoletti, L. Micco, H Singh, Dimitra Peppa
Publikováno v:
The Lancet. 389:S39
Background There is a pressing need for new treatment strategies in chronic hepatitis B. Natural killer (NK) cells are important antiviral effectors, and are potently expanded with peginterferon alfa in chronic hepatitis B. Robust antiviral T-cell re
Autor:
Christian Brander, Anna Schurich, Dimitra Peppa, Pietro Andreone, Lucy Jefferson, L. Micco, Florian Bihl, Elisabetta Loggi, Carmela Cursaro, Mauro Bernardi, Mala K. Maini, Arianna Martello Panno
Background & Aims: A better understanding of the immunomodulatory effects of PegIFNa therapy could allow more rational optimisation of future therapeutic approaches in chronic HBV infection. In this study, we evaluated dynamic changes in the innate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a55040a29694ce3f0c853d463f0595
https://hdl.handle.net/11380/1237220
https://hdl.handle.net/11380/1237220
Autor:
Alessandro Nanni Costa, Paolo Grossi, Antonio Daniele Pinna, L. Micco, Mauro Bernardi, Pietro Andreone, Andrea Bontadini, Stefano Gitto, Gian Luca Grazi, Christian Brander, Alessandro Cucchetti, Giorgio Ercolani, Elisabetta Loggi, Florian Bihl
Publikováno v:
ResearcherID
Background & Aims The main limitation of orthotopic liver transplantation (OLT) is the scarcity of available donor organs. A possibility to increase the organ pool is to use grafts from hepatitis B virus surface antigen (HBsAg) positive donors, but f
Autor:
Mala K. Maini, Anna Schurich, Anna Maria Geretti, Kijun Han, Pooja Khanna, Geoffrey Dusheiko, L. Micco, A. Ross Lopes, G. Nebbia, Patrick T F Kennedy, Dimitra Peppa
Publikováno v:
Hepatology (Baltimore, Md.). 53(5)
An excess of coinhibitory signals has been proposed to drive the T-cell exhaustion characteristic of persistent viral infections. In this study we examined the contribution of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 (CTLA-4) to CD8
Autor:
A, Gramenzi, E, Loggi, L, Micco, C, Cursaro, S, Fiorino, S, Galli, S, Gitto, C, Galli, G, Furlini, M, Bernardi, P, Andreone
Serum hepatitis B virus surface antigen (HBsAg) levels have been suggested to predict interferon response in chronic hepatitis B. A few data are available on the role of HBsAg measurement in nucleos(t)ide analogues (NA) treatment. We retrospectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6902f3e1ef831a094475339657487645
https://hdl.handle.net/11380/1237352
https://hdl.handle.net/11380/1237352
Autor:
Mauro Bernardi, Annagiulia Gramenzi, L. Micco, Roberto Di Donato, Stefano Gitto, Carmela Cursaro, Andrea Cuppini, Fabio Conti, Pietro Andreone, Sirio Fiorino, Elisabetta Loggi
Hepatitis B virus (HBV)- and hepatitis C virus (HCV)-related chronic infections represent a major health problem worldwide. Although the efficacy of HBV and HCV treatment has improved, several important problems remain. Current recommended antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f273b905c5283679511f42f8b363ee
http://hdl.handle.net/11585/98933
http://hdl.handle.net/11585/98933
Autor:
M. Salerno, Carmela Cursaro, Annagiulia Gramenzi, Mauro Bernardi, L. Micco, Stefano Gitto, Fabio Conti, A. Riili, F. Felline, A. Scuteri, Pietro Andreone
Chronic hepatitis C virus (HCV) infection has been poorly investigated in the elderly. The aim of this study was to identify the age-specific characteristics of chronic hepatitis C by comparing patientsor =65 years with those65 years. A cross-section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f880b77060adef74c9089ccd84fc059
https://hdl.handle.net/11380/1237126
https://hdl.handle.net/11380/1237126
Due to their high prevalence in the general population, alcohol use and abuse can be associated with hepatitis B and C virus infections and it has been demonstrated that alcohol plays a role as a co-morbid factor in the development of liver disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332701b208761568a756928083d82b92
http://hdl.handle.net/11585/67393
http://hdl.handle.net/11585/67393