Zobrazeno 1 - 10
of 627
pro vyhledávání: '"L, Maynard"'
Publikováno v:
Adolescents, Vol 3, Iss 1, Pp 41-59 (2022)
Background: Adolescence is a critical developmental period for mentalization and emotion regulation skills. Studies show that during this time, adolescents may experience greater vulnerability to challenges of mental and emotional well-being. Studies
Externí odkaz:
https://doaj.org/article/cb3082ff20ed478c815fb632fabf803e
Autor:
Qing Zhao, Craig L. Maynard
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The immune system in the large intestine is separated from commensal microbes and comparatively rare enteric pathogens by a monolayer of diverse epithelial cells overlaid with a compact and adherent inner mucus layer and a looser outer mucus layer. M
Externí odkaz:
https://doaj.org/article/dc6063ee91264d24b169290083e1699e
Autor:
Wenjing Yang, Tianming Yu, Xiangsheng Huang, Anthony J. Bilotta, Leiqi Xu, Yao Lu, Jiaren Sun, Fan Pan, Jia Zhou, Wenbo Zhang, Suxia Yao, Craig L. Maynard, Nagendra Singh, Sara M. Dann, Zhanju Liu, Yingzi Cong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Intestinal IL-22 has important regulatory effects on the barrier and intestinal diseases and its production is controlled by the intestinal microbiome. Here the authors show that intestinal immune cell production of IL-22 is regulated by short chain
Externí odkaz:
https://doaj.org/article/c31a59e08ef446ffa06978b9286f2500
Autor:
Ejas Palathingal Bava, John George, Mohammad Tarique, Srikanth Iyer, Preeti Sahay, Beatriz Gomez Aguilar, Dujon B. Edwards, Bhuwan Giri, Vrishketan Sethi, Tejeshwar Jain, Prateek Sharma, Utpreksha Vaish, Harrys K. C. Jacob, Anthony Ferrantella, Craig L. Maynard, Ashok K. Saluja, Rajinder K. Dawra, Vikas Dudeja
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Despite decades of research, there is no specific therapy for acute pancreatitis (AP). In the current study, we have evaluated the efficacy of pirfenidone, an antiinflammatory and antifibrotic agent that is approved by the FDA for treatment of idiopa
Externí odkaz:
https://doaj.org/article/5a67edc6225d42e6a846bf7637ca2d15
Autor:
Rachel Q Muir, Barbara J Klocke, Melissa S Jennings, Patrick A Molina, Jung-Shan Hsu, Cailin E Kellum, Katie L Alexander, Goo Lee, Jeremy B Foote, Robin G Lorenz, Jennifer S Pollock, Craig L Maynard
Publikováno v:
Inflammatory Bowel Diseases. 29:960-972
Background Early life stress (ELS) is an environmental trigger believed to promote increased risk of IBD. Our goal was to identify mechanisms whereby ELS in mice affects susceptibility to and/or severity of gut inflammation. Methods We utilized 2 pub
Autor:
Virginia Camacho, Victoria R. Matkins, Sweta B. Patel, Jeremie M. Lever, Zhengqin Yang, Li Ying, Ashley E. Landuyt, Emma C. Dean, James F. George, Henry Yang, Paul Brent Ferrell, Craig L. Maynard, Casey T. Weaver, Heth R. Turnquist, Robert S. Welner
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Externí odkaz:
https://doaj.org/article/1f60283a5d9849e4826f16038c6c5f98
Autor:
Dominique C. Hinshaw, Courtney A. Swain, Dongquan Chen, Ann Hanna, Patrick A. Molina, Craig L. Maynard, Goo Lee, Braden C. McFarland, Rajeev S. Samant, Lalita A. Shevde
Publikováno v:
Laboratory Investigation. 102:1236-1244
Given the gut microbiome's rise as a potential frontier in cancer pathogenesis and therapy, leveraging microbial analyses in the study of breast tumor progression and treatment could unveil novel interactions between commensal bacteria and disease ou
Autor:
Melissa A. Smigelsky, Justin L. Maynard, C. Graham Ford, Ryan Parker, Jennifer H. Wortmann, Keith G. Meador, Anna Fink, Jason A. Nieuwsma
Publikováno v:
Journal of Health Care Chaplaincy. :1-13
The Department of Veterans Affairs (VA) has prioritized improving the identification of veterans at risk for suicide and ensuring adequate staffing of personnel to assist veterans in need. It is imperative that suicide prevention efforts make use of
This invaluable volume, the third in the series Air Pollution Reviews, addresses particular questions relating to air pollution and its effect on health. It deals with the impact of nasal disease on lung exposure, how pollutants are distributed withi
Autor:
Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1659-1677
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted in traditional p