Zobrazeno 1 - 10
of 2 302
pro vyhledávání: '"L, Masters"'
Autor:
Xin Huang, Chris Fowler, Yihan Li, Qiao-Xin Li, Jiaqi Sun, Yijun Pan, Liang Jin, Keyla A. Perez, Céline Dubois, Yen Y. Lim, Candace Drysdale, Rebecca L. Rumble, Holly R. Chinnery, Christopher C. Rowe, Ralph N. Martins, Paul Maruff, James D. Doecke, Yong Lin, Abdel A. Belaidi, Kevin J. Barnham, Colin L. Masters, Ben J. Gu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Impaired clearance of amyloid β (Aβ) in late-onset Alzheimer’s disease (AD) affects disease progression. The role of peripheral monocytes in Aβ clearance from the central nervous system (CNS) is unclear. We use a flow cytometry assay to
Externí odkaz:
https://doaj.org/article/3d0335505eb94001ae1c6a1edbac7289
Autor:
Elina Idiiatullina, Mahmoud Al-Azab, Meng Lin, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, Caiqin Guo, Xixi Chen, Yaoying Li, Song Gao, Jun Cui, Wenhao Zhou, Li Liu, Yuxia Zhang, Seth L. Masters
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Mitochondrial RNA (mtRNA) in the cytosol can trigger the innate immune sensor MDA5, and autoinflammatory disease due to type I IFN. Here, we show that a dominant negative mutation in the gene encoding the mitochondrial exonuclease REXO2 may
Externí odkaz:
https://doaj.org/article/0032191b7af148eb845c8a3117450786
Autor:
Yihan Wang, Shu Liu, Alanna G. Spiteri, Andrew Liem Hieu Huynh, Chenyin Chu, Colin L. Masters, Benjamin Goudey, Yijun Pan, Liang Jin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Several (inter)national longitudinal dementia observational datasets encompassing demographic information, neuroimaging, biomarkers, neuropsychological evaluations, and muti-omics data, have ushered in a new era of potential for integrating
Externí odkaz:
https://doaj.org/article/eefdc1e7f56e408da1410a2f95024c8a
Autor:
Yijun Pan, Chenyin Chu, Yifei Wang, Yihan Wang, Guangyan Ji, Colin L. Masters, Benjamin Goudey, Liang Jin
Publikováno v:
EClinicalMedicine, Vol 76, Iss , Pp 102834- (2024)
Summary: Background: It is estimated that ∼60% of people with Alzheimer's disease (AD) are undetected or undiagnosed, with higher rates of underdiagnosis in low-to middle-income areas with limited medical resources. To promote health equity, we hav
Externí odkaz:
https://doaj.org/article/bd53fa5b9f7c4c4aa85db13d83e65e51
Autor:
Liwei Ma, Yi Ling Clare Low, Yuanhao Zhuo, Chenyin Chu, Yihan Wang, Christopher J. Fowler, Edwin C. K. Tan, Colin L. Masters, Liang Jin, Yijun Pan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract An inverse association between cancer and Alzheimer’s disease (AD) has been demonstrated; however, the association between cancer and mild cognitive impairment (MCI), and the association between cancer and cognitive decline are yet to be c
Externí odkaz:
https://doaj.org/article/69185a15744047ecae83cc500a52be73
Autor:
Julie L. Masters, Patrick W. Josh, Amanda J. Kirkpatrick, Mariya A. Kovaleva, Harlan R. Sayles
Publikováno v:
Palliative Care and Social Practice, Vol 18 (2024)
Background: Palliative care affords numerous benefits, including improvements in symptom management, mental health, and quality of life, financial savings, and decreased mortality. Yet palliative care is poorly understood and often erroneously viewed
Externí odkaz:
https://doaj.org/article/d224940888654d34bd64502aed84412e
Autor:
Cody R. Fisher, Thao L. Masters, Stephen Johnson, Kerryl E. Greenwood-Quaintance, Nicholas Chia, Matthew P. Abdel, Robin Patel
Publikováno v:
International Journal of Medical Microbiology, Vol 315, Iss , Pp 151620- (2024)
Staphylococcus epidermidis is part of the commensal microbiota of the skin and mucous membranes, though it can also act as a pathogen in certain scenarios, causing a range of infections, including periprosthetic joint infection (PJI). Transcriptomic
Externí odkaz:
https://doaj.org/article/b25228c0358544c3b863328633db7bb0
Autor:
Zhijian Yang, Junhao Wen, Ahmed Abdulkadir, Yuhan Cui, Guray Erus, Elizabeth Mamourian, Randa Melhem, Dhivya Srinivasan, Sindhuja T. Govindarajan, Jiong Chen, Mohamad Habes, Colin L. Masters, Paul Maruff, Jurgen Fripp, Luigi Ferrucci, Marilyn S. Albert, Sterling C. Johnson, John C. Morris, Pamela LaMontagne, Daniel S. Marcus, Tammie L. S. Benzinger, David A. Wolk, Li Shen, Jingxuan Bao, Susan M. Resnick, Haochang Shou, Ilya M. Nasrallah, Christos Davatzikos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially r
Externí odkaz:
https://doaj.org/article/e4408877453444c49479a4dba3887d8a
Autor:
Louise N. Pivac, Belinda M. Brown, Kelsey R. Sewell, James D. Doecke, Victor L. Villemagne, Vincent Doré, Michael Weinborn, Hamid R. Sohrabi, Samantha L. Gardener, Romola S. Bucks, Simon M. Laws, Kevin Taddei, Paul Maruff, Colin L. Masters, Christopher Rowe, Ralph N. Martins, Stephanie R. Rainey‐Smith
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION This study investigated whether self‐reported sleep quality is associated with brain amyloid beta (Aβ) accumulation. METHODS Linear mixed effect model analyses were conducted for 189 cognitively unimpaired (CU) older adults (
Externí odkaz:
https://doaj.org/article/752e0f9b15914192953cf6940c065a99
Autor:
Catherine Quynh Nhu Nguyen, Liwei Ma, Yi Ling Clare Low, Edwin C. K. Tan, Christopher Fowler, Colin L. Masters, Liang Jin, Yijun Pan, the AIBL research group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Mounting evidence suggests that certain comorbidities may influence the clinical evolution of Alzheimer's dementia (AD). METHODS We conducted logistic regression analyses on the medical history and cognitive health diagnoses of
Externí odkaz:
https://doaj.org/article/9f0d223638c744ec8dadb2a739696dfc