Zobrazeno 1 - 10
of 1 927
pro vyhledávání: '"L, Margolis"'
Autor:
Michael E. Ernst, Kevin Phan, Mark R. Nelson, Robyn L. Woods, Michelle A. Fravel, Lawrence Beilin, Suzanne G. Orchard, Zhen Zhou, Kevan R. Polkinghorne, Jonathan C. Broder, Karen L. Margolis, Christopher M. Reid, Nigel Stocks, Enayet Chowdhury, Rory Wolfe
Publikováno v:
The Journal of Clinical Hypertension, Vol 26, Iss 10, Pp 1188-1195 (2024)
Abstract High‐quality randomized trial evidence is lacking on whether low‐dose aspirin exerts significant effects on blood pressure (BP) in older adults. The authors assessed longitudinal BP changes in participants enrolled in ASPirin in Reducing
Externí odkaz:
https://doaj.org/article/ebcbc222eca043eca27e9cf819e6a86b
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103441- (2024)
Spinocerebellar ataxia type 12 (SCA12) is caused by a CAG expansion mutation in PPP2R2B, a gene encoding brain-specific regulatory units of protein phosphatase 2A (PP2A); while normal alleles carry 4 to 31 triplets, the disease alleles carry 43 to 78
Externí odkaz:
https://doaj.org/article/08c786ae18024f3eaddac5fa6da5e56f
Autor:
Clarissa Hsu, Laurel Hansell, Kelly Ehrlich, Sean Munson, Melissa Anderson, Karen L. Margolis, Jennifer B. McClure, Yoshio N. Hall, Matthew Thompson, Dwayne Joseph, Beverly B. Green
Publikováno v:
BMC Primary Care, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Early identification and control of hypertension is critical to reducing cardiovascular disease events and death. U.S. Preventive Services Task Force guidelines recommend health care professionals screen all adults for hypertensio
Externí odkaz:
https://doaj.org/article/ba4af570544f4c1a9227799dbef37c2f
Publikováno v:
Health Services Research & Managerial Epidemiology, Vol 10 (2023)
Introduction This analysis is a part of ongoing quality improvement efforts aiming at improving hypertension control among various racial minority groups seen in a large outpatient practice with a special focus on two war refugee populations, the Hmo
Externí odkaz:
https://doaj.org/article/821592b6483445f9a4bc226adccbcaee
Autor:
Karen L. Margolis, A. Lauren Crain, Beverly B. Green, Patrick J. O’Connor, Leif I. Solberg, MarySue Beran, Anna R. Bergdall, Pamala A. Pawloski, Jeanette Y. Ziegenfuss, Meghan M. JaKa, Deepika Appana, Rashmi Sharma, Amy J. Kodet, Nicole K. Trower, Daniel J. Rehrauer, Zeke McKinney, Christine K. Norton, Patricia Haugen, Jeffrey P. Anderson, Benjamin F. Crabtree, Sarah K. Norman, JoAnn M. Sperl-Hillen
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Explanatory trials are designed to assess intervention efficacy under ideal conditions, while pragmatic trials are designed to assess whether research-proven interventions are effective in “real-world” settings without substan
Externí odkaz:
https://doaj.org/article/7bba79f1bcf84180844705bb07633950
Autor:
JoAnn M Sperl-Hillen, Jeffrey P Anderson, Karen L Margolis, Rebecca C Rossom, Kristen M Kopski, Beth M Averbeck, Jeanine A Rosner, Heidi L Ekstrom, Steven P Dehmer, Patrick J O’Connor
Publikováno v:
JMIR Formative Research, Vol 6, Iss 10, p e32666 (2022)
BackgroundLimited budgets may often constrain the ability of health care delivery systems to adopt shared decision-making (SDM) systems designed to improve clinical encounters with patients and quality of care. ObjectiveThis study aimed to assess th
Externí odkaz:
https://doaj.org/article/22cdd854820447c89594c207c7aee277
Autor:
Maxine L. Margolis
Brazil, a country that has always received immigrants, only rarely saw its own citizens move abroad. Beginning in the late 1980s, however, thousands of Brazilians left for the United States, Japan, Portugal, Italy, and other nations, propelled by a s
Autor:
Sheila M. Manemann, Yariv Gerber, Suzette J. Bielinski, Alanna M. Chamberlain, Karen L. Margolis, Susan A. Weston, Jill M. Killian, Véronique L. Roger
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background The rate of decline in cardiovascular disease (CVD) mortality has lessened nationally. How these findings apply to specific states or causes of CVD deaths is not known. Examining these trends at the state level is important to pla
Externí odkaz:
https://doaj.org/article/921815041023464b9b216af3bf938faf
Autor:
Pan P. Li, Russell L. Margolis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cas9 nucleases permit rapid and efficient generation of gene-edited cell lines. However, in typical protocols, mutations are intentionally introduced into the donor template to avoid the cleavage of donor template or re-cleavage of the succe
Externí odkaz:
https://doaj.org/article/b8d48dc1c8e94fc1be92edab617e9721
Autor:
Nam-Shik Kim, Zhexing Wen, Jing Liu, Ying Zhou, Ziyuan Guo, Chongchong Xu, Yu-Ting Lin, Ki-Jun Yoon, Junhyun Park, Michelle Cho, Minji Kim, Xinyuan Wang, Huimei Yu, Srilatha Salamuru, Kimberly M. Christian, Kuei-sen Hsu, Menghang Xia, Weidong Li, Christopher A. Ross, Russell L. Margolis, Xin-Yun Lu, Hongjun Song, Guo-li Ming
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Previous work has shown in iPSC derived neurons that synaptic impairments are associated with a 4bp DISC1 deletion. Here the authors demonstrate a role for the PDE4 signalling pathway in these synaptic impairments.
Externí odkaz:
https://doaj.org/article/a1c93081300b4869a2a2b16a518720f6