Zobrazeno 1 - 10
of 29
pro vyhledávání: '"L, Kear"'
Autor:
Mayandi, Sivaguru, Jessica J, Saw, Elena M, Wilson, John C, Lieske, Amy E, Krambeck, James C, Williams, Michael F, Romero, Kyle W, Fouke, Matthew W, Curtis, Jamie L, Kear-Scott, Nicholas, Chia, Bruce W, Fouke
Publikováno v:
Nature reviews. Urology. 18(7)
GeoBioMed - a new transdisciplinary approach that integrates the fields of geology, biology and medicine - reveals that kidney stones composed of calcium-rich minerals precipitate from a continuum of repeated events of crystallization, dissolution an
Autor:
Jamie L. Kear-Scott, Gail E. Fanucci, Angelo M. Veloro, Luis Galiano, Mandy E. Blackburn, Xi Huang, Zhanglong Liu, Linh Pham, Ian Mitchelle S. de Vera, Thomas M. Casey, Jeffrey D. Carter
Publikováno v:
Physical Chemistry Chemical Physics. 18:5819-5831
The conformational landscape of HIV-1 protease (PR) can be experimentally characterized by pulsed-EPR double electron-electron resonance (DEER). For this characterization, nitroxide spin labels are attached to an engineered cysteine residue in the fl
Autor:
Carlos Simmerling, Xi Huang, Gail E. Fanucci, Ben M. Dunn, Jamie L. Kear-Scott, Manuel D. Britto, Robert McKenna, Michael Bieri, Christopher D. Boone, Paul R. Gooley, James R. Rocca
Publikováno v:
Journal of Biological Chemistry. 289:17203-17214
HIV-1 protease is an essential enzyme for viral particle maturation and is a target in the fight against HIV-1 infection worldwide. Several natural polymorphisms are also associated with drug resistance. Here, we utilized both pulsed electron double
Publikováno v:
Journal of Biophysical Chemistry. :137-146
Site-directed spin-labeling with continuous wave electron paramagnetic resonance spectroscopy was used to monitor autoproteolysis of HIV-1 protease, an enzyme essential for viral maturation. Two protein constructs were examined, namely subtype F and
Publikováno v:
Analytica Chimica Acta. 478:245-258
Real-time measurement of total oil concentration in complex samples is required in wastewater discharge streams from ships and processing industries. A novel technology has been developed for the accurate quantification of a variety of single oils an
Autor:
Joshua A. Riback, Jamie L. Kear-Scott, Tobin R. Sosnick, Evgeny V. Pilipenko, D. Allan Drummond, Christopher A. Katanski
Publikováno v:
Biophysical Journal. 112:5a
In eukaryotic cells, a variety of stresses trigger the coalescence of RNA-binding proteins into stress granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels, and other assemblies lacking fixed stoichiometry. Obse
Autor:
James R. Rocca, Mandy E. Blackburn, Gail E. Fanucci, Carlos Simmerling, Xi Huang, Jeffery D. Carter, Angelo M. Veloro, Ian Mitchelle S. de Vera, Ben M. Dunn, Jamie L. Kear
Publikováno v:
The journal of physical chemistry. B. 116(49)
Double electron-electron resonance (DEER) spectroscopy was utilized to investigate shifts in conformational sampling induced by nine FDA-approved protease inhibitors (PIs) and a nonhydrolyzable substrate mimic for human immunodeficiency virus type 1
Autor:
Lesley Early, David C. McGiffin, Geoffrey J. McLachlan, Andrew J. Galbraith, Mark F. O'Brien, Peter Pohlner, M. A. H. Gardner, L. Kear, E. G. Stafford
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 106:895-911
From September 1967 to January 1990, a total of 2100 patients underwent 2366 aortic valve replacements with a variety of allograft, xenograft, and mechanical valves. Concomitant procedures were performed in 764 patients. Actuarial survival at 12 year
Autor:
Brad Davidson, Peter F. Seligman, Lora L. Kear, Roy L. Fransham, Aldis O. Valkirs, Joseph G. Grovhoug
Publikováno v:
Marine Environmental Research. 32:151-167
Tributyltin (TBT) surface water concentrations have significantly decreased in San Diego Bay following legislative restrictions on use of anti-fouling paints containing TBT in California. Current surface water concentrations in three of four regions