Zobrazeno 1 - 10
of 1 300
pro vyhledávání: '"L, Kan"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/937d30e2c13e4d52ab987fd997d1d58e
Autor:
Varsha P. Desai, Jihed Chouaref, Haoyu Wu, William A. Pastor, Ryan L. Kan, Harald M. Oey, Zheng Li, Jamie Ho, Kelly K. D. Vonk, David San Leon Granado, Michael A. Christopher, Amander T. Clark, Steven E. Jacobsen, Lucia Daxinger
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Background Microrchidia proteins (MORCs) are involved in epigenetic gene silencing in a variety of eukaryotic organisms. Deletion of MORCs result in several developmental abnormalities and their dysregulation has been implicated in developme
Externí odkaz:
https://doaj.org/article/6a9ba9b297874f7ca3dba29dbcb2f709
Publikováno v:
APL Bioengineering, Vol 6, Iss 3, Pp 030401-030401-5 (2022)
Externí odkaz:
https://doaj.org/article/6ddae886ccff4afbb17484a16a164f06
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The innate immune response controls the acute phase of virus infections; critical to this response is the induction of type I interferon (IFN) and resultant IFN-stimulated genes to establish an antiviral environment. One such gene, zinc finger antivi
Externí odkaz:
https://doaj.org/article/daedce4d260c4c5ca0222000616a3c7d
Autor:
Ming Wang, Zhenhui Zhong, Javier Gallego-Bartolomé, Zheng Li, Suhua Feng, Hsuan Yu Kuo, Ryan L. Kan, Hoiyan Lam, John Curtis Richey, Linli Tang, Jessica Zhou, Mukun Liu, Yasaman Jami-Alahmadi, James Wohlschlegel, Steven E. Jacobsen
Publikováno v:
Nature plants, vol 9, iss 3
DNA methylation has been utilized for target gene silencing in plants. However, it is not well understood whether other silencing pathways can be also used to manipulate gene expression. Here we performed a gain-of-function screen for proteins that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1632e036760cc43fc82f306ad5a2615f
https://doi.org/10.1038/s41477-023-01362-8
https://doi.org/10.1038/s41477-023-01362-8
Autor:
Wilson Y. K. Chan, W. L. Yeung, Wong S. N. Shelia, Winnie W. Y. Tso, Claudia Cheung, Elaine Y. L. Kan, Pamela P. W. Lee, Daniel K. L. Cheuk, Shau Yin Ha, Wing Leung
Publikováno v:
Experimental and Clinical Transplantation. 21:279-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfdc282465e33a7497f5f78b005ae62d
https://doi.org/10.6002/ect.2022.0383
https://doi.org/10.6002/ect.2022.0383
Autor:
Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Winnie L. Kan, Emma F. Barry, Mara Dottore, Karen S. Cheung Tung Shing, Craig J. Morton, Urmi Dhagat, Matthew P. Hardy, Nicholas J. Wilson, Matthew T. Downton, Christine Schieber, Timothy P. Hughes, Angel F. Lopez, Michael W. Parker
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The N-terminal domain (NTD) of interleukin-3 receptor α-subunit (IL3Rα) is involved in IL-3 recognition but the underlying mechanism is unknown. Here, the authors present crystal structures of the IL3Rα complex and provide biochemical evidence tha
Externí odkaz:
https://doaj.org/article/a177e8976263487282e8d1895527256b
Publikováno v:
THE BULLETIN. 5:286-297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6ccdc8d4c8eb7585f79107d5f196b2
https://doi.org/10.32014/2022.2518-1467.377
https://doi.org/10.32014/2022.2518-1467.377
Autor:
Katharine L. Kan
Summer reading programs are a staple in libraries nationwide and provide a valuable service: keeping teens productive and occupied when they are no longer busy in school. Producing creative programs at the library can be challenging when faced with t
Autor:
Winnie L. Kan, Urmi Dhagat, Kerstin B. Kaufmann, Timothy R. Hercus, Tracy L. Nero, Andy GX. Zeng, John Toubia, Emma F. Barry, Sophie E. Broughton, Guillermo A. Gomez, Brooks A. Benard, Mara Dottore, Karen S. Cheung Tung Shing, Helena Boutzen, Saumya E. Samaraweera, Kaylene J. Simpson, Liqing Jin, Gregory J. Goodall, C. Glenn Begley, Daniel Thomas, Paul G. Ekert, Denis Tvorogov, Richard J. D'Andrea, John E. Dick, Michael W. Parker, Angel F. Lopez
Publikováno v:
Cancer Discovery.
Leukemia stem cells (LSC) possess distinct self-renewal and arrested differentiation properties that are responsible for disease emergence, therapy failure and recurrence in acute myeloid leukemia (AML). Despite AML displaying extensive biological an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc41572709858062712a31dec8e1417
https://doi.org/10.1158/2159-8290.cd-22-1396
https://doi.org/10.1158/2159-8290.cd-22-1396