Zobrazeno 1 - 10
of 85
pro vyhledávání: '"L, Ince"'
Autor:
Natalia A. Ilyushina, Takashi E. Komatsu, William L. Ince, Eric F. Donaldson, Nicolette Lee, Julian J. O’Rear, Raymond P. Donnelly
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations
Externí odkaz:
https://doaj.org/article/d26eb6e3cedd43168e4d091b4fc2e0b7
Autor:
Ivan Kosik, William L Ince, Lauren E Gentles, Andrew J Oler, Martina Kosikova, Matthew Angel, Javier G Magadán, Hang Xie, Christopher B Brooke, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007141 (2018)
[This corrects the article DOI: 10.1371/journal.ppat.1006796.].
Externí odkaz:
https://doaj.org/article/8ef0ef546f97472ab7d79fbed02fcebc
Autor:
Ivan Kosik, William L Ince, Lauren E Gentles, Andrew J Oler, Martina Kosikova, Matthew Angel, Javier G Magadán, Hang Xie, Christopher B Brooke, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006796 (2018)
Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in human populations despite widespread herd immunity. Understanding viral mechanisms that enable antigenic evolution is critical for designing durable vaccines a
Externí odkaz:
https://doaj.org/article/a8d6e151814b4d49b5ff844bb40bacbc
Publikováno v:
The Journal of Infectious Diseases. 222:957-961
Influenza viruses harboring treatment-emergent I38F/M/N/T substitutions in the polymerase acidic (PA) endonuclease exhibited reduced susceptibility to baloxavir and were associated with virus rebound and variable clinical response in clinical trials.
Autor:
Gregory M. Frank, Davide Angeletti, William L. Ince, James S. Gibbs, Surender Khurana, Adam K. Wheatley, Edward E. Max, Adrian B. McDermott, Hana Golding, James Stevens, Jack R. Bennink, Jonathan W. Yewdell
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Antibody (Ab) affinity maturation enables an individual to maintain immunity to an increasing number of pathogens within the limits of a total Ig production threshold. A better understanding of this process is critical for designing vaccines
Externí odkaz:
https://doaj.org/article/b5878bacd8b24a17bf9b60102e41b1e6
Autor:
Javier G Magadán, Meghan O Altman, William L Ince, Heather D Hickman, James Stevens, Aaron Chevalier, David Baker, Patrick C Wilson, Rafi Ahmed, Jack R Bennink, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004204 (2014)
Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA stem is highly conserved between influenza virus strains, HA stem-reactive antibodies
Externí odkaz:
https://doaj.org/article/74024ffa48a944a1a6108bc9315387d3
Autor:
Irwyn L. Ince Jr
Sometimes hope can feel like a scam—a swindle, a hustle. You thought it was real, and you bought into it. But then the tables turn, and you feel like you've been hustled—like you've been had.As Christians, we often respond to the brokenness of li
Autor:
Eric F. Donaldson, William L. Ince, Julian J. O’Rear, Takashi E. Komatsu, Natalia A. Ilyushina, Raymond P. Donnelly, Nicolette Lee
Publikováno v:
Virology Journal
Virology Journal, Vol 16, Iss 1, Pp 1-9 (2019)
Virology Journal, Vol 16, Iss 1, Pp 1-9 (2019)
Background Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations in the in
Autor:
Irwyn L. Ince
Outreach Resource of the YearThe Gospel Coalition Book AwardThe church is at its best when it pursues the biblical value of unity in diversity.Our world has been torn asunder by racial, ethnic, and ideological differences. It is seen in our politics,
Autor:
G, Caratti, T, Poolman, R J, Hurst, L, Ince, A, Knight, K, Krakowiak, H J, Durrington, J, Gibbs, K J, Else, L C, Matthews, D W, Ray
Publikováno v:
Scientific Reports
Glucocorticoids (Gcs) are widely prescribed anti-inflammatory compounds, which act through the glucocorticoid receptor (GR). Using an unbiased proteomics screen in lung tissue, we identified the membrane protein caveolin -1 (Cav1) as a direct interac