Zobrazeno 1 - 10
of 43
pro vyhledávání: '"L, Houlihan"'
Autor:
Katherine L. Houlihan, Petros P. Keoseyan, Amber N. Juba, Tigran Margaryan, Max E. Voss, Alexander M. Babaoghli, Justin M. Norris, Greg J. Adrian, Artak Tovmasyan, Lori M. Buhlman
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2068 (2022)
Loss-of-function parkin mutations cause oxidative stress and degeneration of dopaminergic neurons in the substantia nigra. Several consequences of parkin mutations have been described; to what degree they contribute to selective neurodegeneration rem
Externí odkaz:
https://doaj.org/article/0a4f97b900d54a4d906ec63392368cf1
Publikováno v:
eLife, Vol 5 (2016)
Neuronal fate-restricted intermediate progenitors (IPs) are derived from the multipotent radial glia (RGs) and serve as the direct precursors for cerebral cortical neurons, but factors that control their neurogenic plasticity remain elusive. Here we
Externí odkaz:
https://doaj.org/article/679c08567e5845b4bba249d3e16996c5
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc52e8d5481ae1637a6303983e8783d
https://doi.org/10.1007/978-1-0716-1266-8_33
https://doi.org/10.1007/978-1-0716-1266-8_33
Autor:
Shauna L Houlihan, Yuanyi Feng
Publikováno v:
eLife, Vol 3 (2014)
Successfully completing the S phase of each cell cycle ensures genome integrity. Impediment of DNA replication can lead to DNA damage and genomic disorders. In this study, we show a novel function for NDE1, whose mutations cause brain developmental d
Externí odkaz:
https://doaj.org/article/09978e81c0744e2698a048d9a2f83c21
Autor:
Christian M. Metallo, Joanna Triscott, Ryan M. Loughran, Matthias Reist, Christof Fellmann, Brooke M. Emerling, Lavinia Palamiuc, Rachel J. Lew, Mark A. Rubin, Archna Ravi, Avi Kumar, Chantal Pauli, Vivian Tieu, Shauna L. Houlihan, Gurpreet K. Arora
Publikováno v:
Dev Cell
Summary PI5P4Ks are a class of phosphoinositide kinases that phosphorylate PI-5-P to PI-4,5-P2. Distinct localization of phosphoinositides is fundamental for a multitude of cellular functions. Here, we identify a role for peroxisomal PI-4,5-P2 genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20feaabe2d446735479d086b4720e03b
https://doi.org/10.5167/uzh-204874
https://doi.org/10.5167/uzh-204874
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2276
Disruptions in mitochondrial redox activity are implicated in maladies ranging from those in which cells degenerate to those in which cell division is unregulated. This is not surprising given the pivotal role of mitochondria as ATP producers, reacti
Autor:
Timour Baslan, Darjus F. Tschaharganeh, Shauna L. Houlihan, Gadi Lalazar, Edward R. Kastenhuber, Chi-Chao Chen, Sanford M. Simon, Sha Tian, Benedikt Bosbach, David Requena, Scott W. Lowe, John E. Wilkinson
Publikováno v:
Proceedings of the National Academy of Sciences. 114:13076-13084
A segmental deletion resulting in DNAJB1-PRKACA gene fusion is now recognized as the signature genetic event of fibrolamellar hepatocellular carcinoma (FL-HCC), a rare but lethal liver cancer that primarily affects adolescents and young adults. Here,
Autor:
Christina Curtis, Sarah E. Pierce, Jose A. Seoane, Laura D. Attardi, Shauna L. Houlihan, Kathryn T. Bieging-Rolett, Andrew J. Connolly, Michael C. Bassik, Monte M. Winslow, Changyu Zhu, Anthony M. Boutelle, David W. Morgens, Ian P. Winters, Jacob McClendon, Alyssa M. Kaiser, Gene W. Yeo, Eric L. Van Nostrand, Brian A. Yee, Stephano S. Mello, Scott W. Lowe, Mengxiong Wang
Publikováno v:
Molecular cell, vol 80, iss 3
Mol Cell
Mol Cell
Although TP53 is the most commonly mutated gene in human cancers, the p53-dependent transcriptional programs mediating tumor suppression remain incompletely understood. Here, to uncover critical components downstream of p53 in tumor suppression, we p
Autor:
Shauna L. Houlihan, John P. Morris, Ryan M. Smolkin, Ronald C. Hendrickson, Direna Alonso-Curbelo, Hsuan-An Chen, Yu-Jui Ho, Scott W. Lowe, Wei Luan
Publikováno v:
Cancer Research. 80:A29-A29
Senescence is a cell cycle arrest program that limits the expansion of damaged cells and can trigger antitumor immunity that leads to their elimination in vivo, serving as a potent barrier to tumorigenesis. However, during tumor initiation, the effec
Publikováno v:
Mindfulness. 7:59-67
This paper discusses results from the first empirical study testing the feasibility and effectiveness of an audio-guided mindful awareness training program on quarterly grade performance in traditional US public elementary schools. Structured as a qu