Zobrazeno 1 - 10
of 200
pro vyhledávání: '"L, Hornez"'
Autor:
J.-P. Peyrat, A. Kramar, C. Fournier, F. Révillion, C. Desauw, L. Hornez, E. Blot, J. Bonneterre
Publikováno v:
Oncology Reports. 29:355-361
A pathological complete response (pCR) after neoadjuvant chemotherapy is observed in approximately 20% of breast cancer patients. A proteomic analysis was performed on plasma and tumor tissue before treatment to evaluate its potential impact on the p
Publikováno v:
Annals of Oncology. 19:73-80
Background The aim of this study is to provide an expression profile of ErbB/HER ligands in breast cancer. We analysed the relationships with their receptors, the bio-pathological features and prognosis. Patients and methods Epidermal growth factor (
Publikováno v:
Biochemical Pharmacology. 48:709-716
Multidrug resistance (MDR) corresponds to the cross-over resistance of tumour cells to structurally unrelated cytotoxic chemotherapeutic drugs. One of the mechanisms causing this resistance is the enhanced expression of a transmembrane drug efflux pu
Publikováno v:
International journal of oncology. 1(5)
Cell surface associated proteoglycans were isolated from MCF-7 breast tumor cells by mild trypsin digestion, extraction by guanidine-hydrochloride and purification by ion-exchange chromatography. Immunological studies showed that transferrin can bind
Publikováno v:
International journal of oncology. 2(4)
The growth of normal human breast epithelial cells in vitro, as well as those of other cell types is strongly influenced by the concentration of calcium in the culture medium [Ca++]e. The aim of this study was to ascertain if calcium also affects bre
Publikováno v:
European Journal of Endocrinology
European Journal of Endocrinology, BioScientifica, 2001, 145, pp.763-770
European Journal of Endocrinology, BioScientifica, 2001, 145, pp.763-770
OBJECTIVE: Steroid hormones (estradiol and progesterone) in association with prolactin and growth hormone are involved in lobulo alveolar development of the mammary gland during pregnancy. We hypothesized that the BRCA1 gene may be induced by these d
Autor:
S, Descamps, V, Pawlowski, F, Révillion, L, Hornez, M, Hebbar, B, Boilly, H, Hondermarck, J P, Peyrat
Publikováno v:
Cancer research. 61(11)
Nerve growth factor (NGF) has been shown recently to be mitogenic for human breast cancer cells. In the present study, we have assayed the expression of NGF receptors (NGFRs: TrkA and p75) mRNAs in 363 human primary breast cancers, using real-time qu
Publikováno v:
Anticancer research. 20(5C)
We performed a competitive binding study with 125I-labelled FGF (fibroblast growth factor)-2 and unlabelled FGF-2 in an unselected series of two hundred and thirty human primary breast cancers. One hundred and ninety-two breast cancer biopsies posses
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(11)
We measured the expression of the type I growth factor receptor gene family [epidermal growth factor receptor (EGFR), c-erbB-2, c-erbB-3 and c-erbB-4] in a series of 365 unselected primary breast cancers. The expression was quantified with a real-tim
Publikováno v:
Cancer detection and prevention. 24(3)
We developed a real-time one-step reverse transcriptase-polymerase chain reaction (RT-PCR) method for the routine quantification of c-erbB-2 oncogene expression in breast cancer, using a 7700 ABI PRISM Sequence Detector System (Perkin Elmer-Applied B