Zobrazeno 1 - 10
of 1 595
pro vyhledávání: '"L, Hauser"'
Autor:
Tobias Derfuss, Robert Bermel, Chien-Ju Lin, Stephen L. Hauser, Ludwig Kappos, Timothy Vollmer, Giancarlo Comi, Gavin Giovannoni, Hans-Peter Hartung, Martin S. Weber, Jianmei Wang, Nikki Jessop, Cathy Chognot, Licinio Craveiro, Amit Bar-Or
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Patients with multiple sclerosis (PwMS) have an increased risk of infections. Objectives: To characterize incidence, clinical characteristics, outcomes and risk factors of infections, and serious infections (SIs) in ocrelizumab (OCR)-trea
Externí odkaz:
https://doaj.org/article/aed1889aa6044652a518886ae29cb31b
Autor:
Tanuja Chitnis, Ferhan Qureshi, Victor M. Gehman, Michael Becich, Riley Bove, Bruce A. C. Cree, Refujia Gomez, Stephen L. Hauser, Roland G. Henry, Amal Katrib, Hrishikesh Lokhande, Anu Paul, Stacy J. Caillier, Adam Santaniello, Neda Sattarnezhad, Shrishti Saxena, Howard Weiner, Hajime Yano, Sergio E. Baranzini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The multifaceted nature of multiple sclerosis requires quantitative biomarkers that can provide insights related to diverse physiological pathways. To this end, proteomic analysis of deeply-phenotyped serum samples, biological pathway modeli
Externí odkaz:
https://doaj.org/article/833d8dd5aeba4eed913b4c923942db14
Autor:
Jeannette Lechner-Scott, Wenjia Wei, Heinz Wiendl, Xavier Montalban, Stephen L Hauser, Tjalf Ziemssen, Douglas L Arnold, Enrique Alvarez, Tobias Derfuss, Thomas P Leist, Alit Bhatt, Ibolya Boer
Publikováno v:
BMJ Neurology Open, Vol 6, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/2bf9db0e6f674b30b91492c0baf3b545
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Familiarity creates subjective memory of repeated innocuous experiences, reduces neural and behavioral responsiveness to those experiences, and enhances novelty detection. The neural correlates of the internal model of familiarity and the ce
Externí odkaz:
https://doaj.org/article/c9c9d4108ec64dad9ff99fdc98502c9a
Autor:
Stephen L. Hauser, Ludwig Kappos, Amit Bar-Or, Heinz Wiendl, David Paling, Mitzi Williams, Ralf Gold, Andrew Chan, Ron Milo, Ayan Das Gupta, Goeril Karlsson, Roseanne Sullivan, Gordon Graham, Martin Merschhemke, Dieter A. Häring, Patrick Vermersch
Publikováno v:
Neurology and Therapy, Vol 12, Iss 5, Pp 1491-1515 (2023)
Abstract The importance of B cells in multiple sclerosis (MS) has been demonstrated through the advent of B-cell-depleting anti-CD20 antibody therapies. Ofatumumab is the first fully human anti-CD20 monoclonal antibody (mAb) developed and tested for
Externí odkaz:
https://doaj.org/article/eebd67c7598744dda6a94266f7a71dd5
Autor:
Qin Ma, Danillo G. Augusto, Gonzalo Montero-Martin, Stacy J. Caillier, Kazutoyo Osoegawa, Bruce A. C. Cree, Stephen L. Hauser, Alessandro Didonna, Jill A. Hollenbach, Paul J. Norman, Marcelo Fernandez-Vina, Jorge R. Oksenberg
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe HLA-DRB1 gene in the major histocompatibility complex (MHC) region in chromosome 6p21 is the strongest genetic factor identified as influencing multiple sclerosis (MS) susceptibility. DNA methylation changes associated with MS have been
Externí odkaz:
https://doaj.org/article/e17816670eb94ed78dd6ec595e2f543c
Autor:
Qin Ma, Hengameh Shams, Alessandro Didonna, Sergio E. Baranzini, Bruce A. C. Cree, Stephen L. Hauser, Roland G. Henry, Jorge R. Oksenberg
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
The combined analysis of single cell and bulk epigenetic datasets and multiple sclerosis GWAS reveals the enrichment of genetic susceptibility signals in B cells and monocyte-microglia cell types.
Externí odkaz:
https://doaj.org/article/675d0cabbd474edfbffe9c5abc5657bf
Autor:
Amit Bar-Or, Gian-Andrea Thanei, Christopher Harp, Corrado Bernasconi, Ulrike Bonati, Anne H. Cross, Saloumeh Fischer, Laura Gaetano, Stephen L. Hauser, Robert Hendricks, Ludwig Kappos, Jens Kuhle, David Leppert, Fabian Model, Annette Sauter, Harold Koendgen, Xiaoming Jia, Ann E. Herman
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104662- (2023)
Summary: Background: Neurofilament light chain (NfL), a neuronal cytoskeletal protein that is released upon neuroaxonal injury, is associated with multiple sclerosis (MS) relapsing activity and has demonstrated some prognostic ability for future rela
Externí odkaz:
https://doaj.org/article/e7ff9f024a2e4966833fd5346456e54f
Autor:
Suraj Niraula, Julia J. Doderer, Shreya Indulkar, Kalen P. Berry, William L. Hauser, Oliver J. L’Esperance, Jasmine Z. Deng, Griffin Keeter, Adam G. Rouse, Jaichandar Subramanian
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111946- (2023)
Summary: Neuronal hyperactivity induces memory deficits in Alzheimer’s disease. However, how hyperactivity disrupts memory is unclear. Using in vivo synaptic imaging in the mouse visual cortex, we show that structural excitatory-inhibitory synapse
Externí odkaz:
https://doaj.org/article/66dd86b193b849939e44d1a66a505d3b
Autor:
F. Arntz, B. Mkaouer, A. Markov, B. J. Schoenfeld, J. Moran, R. Ramirez-Campillo, M. Behrens, P. Baumert, R. M. Erskine, L. Hauser, H. Chaabene
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Objective: To examine the effect of plyometric jump training on skeletal muscle hypertrophy in healthy individuals.Methods: A systematic literature search was conducted in the databases PubMed, SPORTDiscus, Web of Science, and Cochrane Library up to
Externí odkaz:
https://doaj.org/article/bc7f2ae73d80454e99a0be6cc13d6b71