Zobrazeno 1 - 10
of 511
pro vyhledávání: '"L, Harden"'
Autor:
John J. Millichap, Cynthia L. Harden, Dennis J. Dlugos, Jacqueline A. French, Noam N. Butterfield, Celene Grayson, Ernesto Aycardi, Simon N. Pimstone
Publikováno v:
Epilepsia Open, Vol 6, Iss 1, Pp 38-44 (2021)
Abstract Literature review of patients with KCNQ2 developmental and epileptic encephalopathy (KCNQ2‐DEE) reveals, based on 16 reports including 139 patients, a clinical phenotype that includes age‐ and disease‐specific stereotyped seizures. The
Externí odkaz:
https://doaj.org/article/19ac3bfee377407aa43fcd3590325a6b
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 24, Iss , Pp 321-324 (2021)
Objectives: Klebsiella michiganensis is an emerging pathogen implicated in nosocomial infections. Here we report on the resistome, virulome and mobilome of a carbapenemase-producing K. michiganensis isolate from urban hospital effluent in Pietermarit
Externí odkaz:
https://doaj.org/article/969f31b7982845fb88d3ffbd79b504f1
Publikováno v:
Journal of Nursing Education. 62:279-284
Background: Palliative care (PC) focuses on listening to patient preferences, goals, and values to help health care providers educate, support, and collaborate during challenging disease processes, demanding treatments, and difficult decision-making.
Relationship between rheology and structure of interpenetrating, deforming and compressing microgels
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Thermosensitive microgels are widely studied polymer-colloid hybrids but their interactions and packing are still not fully understood. Here, the authors study the linear viscoelasticity of dense microgels and analyse the local particle structure and
Externí odkaz:
https://doaj.org/article/260f66c087124265a926d14d51895a4f
Autor:
Sarah L. Harden, Jieliang Zhou, Seley Gharanei, Maria Diniz-da-Costa, Emma S. Lucas, Liang Cui, Keisuke Murakami, Jinling Fang, Qingfeng Chen, Jan J. Brosens, Yie Hou Lee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Differentiation of endometrial fibroblasts into specialized decidual cells controls embryo implantation and transforms the cycling endometrium into a semi-permanent, immune-protective matrix that accommodates the placenta throughout pregnancy. This p
Externí odkaz:
https://doaj.org/article/72dd938faead4393ac3ede7955b79b84
Publikováno v:
APL Bioengineering, Vol 4, Iss 3, Pp 036107-036107-14 (2020)
Characterizing the time-dependent mechanical properties of cells is not only necessary to determine how they deform but also to understand how external forces trigger biochemical-signaling cascades to govern their behavior. At present, mechanical pro
Externí odkaz:
https://doaj.org/article/c17992d5bbc04be0b177a8e5402fc7da
Autor:
Ammon E Posey, Mehran Bagheri, Kyle A Ross, Elizabeth N Lanum, Mish A Khan, Christine M Jennings, Megan C Harwig, Nolan W Kennedy, Vincent J Hilser, James L Harden, R. Blake Hill
Publikováno v:
bioRxiv
Dynamins are an essential superfamily of mechanoenzymes that remodel membranes and often contain a "variable domain" (VD) important for regulation. For the mitochondrial fission dynamin, Drp1, a regulatory role for the VD is demonstrated by mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430c75b1ef6f9aef1cdf0c61feab456b
https://europepmc.org/articles/PMC10312466/
https://europepmc.org/articles/PMC10312466/
Autor:
Gavin J. Donley, Suresh Narayanan, Matthew A. Wade, Jun Dong Park, Robert L. Leheny, James L. Harden, Simon A. Rogers
Publikováno v:
Proceedings of the National Academy of Sciences. 120
We probe the microstructural yielding dynamics of a concentrated colloidal system by performing creep/recovery tests with simultaneous collection of coherent scattering data via X-ray Photon Correlation Spectroscopy (XPCS). This combination of rheolo
Autor:
Stephen M. Thirdborough, Gareth J. Thomas, Christopher H. Woelk, Jeongmin Woo, Oliver Wood, Jason Fleming, Veronika Jenei, Jana Stasakova, Elena L. Harden, Kate L. Perry, Christian H. Ottensmeier
Figure S3. Increased expression of the CD8+ T-cell signature has a prognostic value for overall survival. (A and B) Kaplan-Meier estimates of overall survival among patients grouped according to expression of genes with the strongest membership (kME{
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5952b780779b474c6f12702231a203
https://doi.org/10.1158/0008-5472.22411931
https://doi.org/10.1158/0008-5472.22411931
Autor:
Stephen M. Thirdborough, Gareth J. Thomas, Christopher H. Woelk, Jeongmin Woo, Oliver Wood, Jason Fleming, Veronika Jenei, Jana Stasakova, Elena L. Harden, Kate L. Perry, Christian H. Ottensmeier
Antibodies that block T-cell–regulatory checkpoints have recently emerged as a transformative approach to cancer treatment. However, the clinical efficacy of checkpoint blockade depends upon inherent tumor immunogenicity, with variation in infiltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a4224ea36aaf29a073eeb3b575e4788
https://doi.org/10.1158/0008-5472.c.6508331.v1
https://doi.org/10.1158/0008-5472.c.6508331.v1