Zobrazeno 1 - 10
of 170
pro vyhledávání: '"L, Hagemann"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/c8a7bb495d784a699e22801c2b343fb6
Autor:
Michelle M. Boyd, Suzanne J. Litscher, Laura L. Seitz, Albee Messing, Tracy L. Hagemann, Lara S. Collier
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Alexander disease (AxD) is a rare neurodegenerative disorder that is caused by dominant mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament that is primarily expressed by astrocytes. In
Externí odkaz:
https://doaj.org/article/1f287bbee59c40abaa415f56c48a0634
Publikováno v:
Cells, Vol 12, Iss 7, p 978 (2023)
Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system. AxD-associated mutations cause GFAP aggregation and astrogliosis, a
Externí odkaz:
https://doaj.org/article/73cf2e06e61d4e96bc33ab64935f77de
Autor:
Liqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann, Jeffrey R. Jones, Ernest Fraenkel, David A. Weitz, Su-Chun Zhang, Albee Messing, Mel B. Feany
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Alexander disease is a rare neurodegeneration caused by mutations in a glial gene GFAP. Here, Wang and colleagues show in animal models of Alexander disease that GFAP mutant brain and cells have greater tissue and cellular stiffness and greater activ
Externí odkaz:
https://doaj.org/article/36c12df858ac434183e838e24dc960c5
Autor:
Tracy L. Hagemann
Publikováno v:
Curr Opin Neurobiol
Alexander disease is a primary disorder of astrocytes caused by gain-of-function mutations in the gene for glial fibrillary acidic protein (GFAP), which lead to protein aggregation and a reactive astrocyte response, with devastating effects on the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55905bca17a234632fa42e8c6d00cb2
https://doi.org/10.1016/j.conb.2021.10.002
https://doi.org/10.1016/j.conb.2021.10.002
Autor:
Liqun Wang, Hassan Bukhari, Linghai Kong, Tracy L. Hagemann, Su-Chun Zhang, Albee Messing, Mel B. Feany
Publikováno v:
J Neurosci
Anastasis is a recently described process in which cells recover after late-stage apoptosis activation. The functional consequences of anastasis for cells and tissues are not clearly understood. UsingDrosophila, rat and human cells and tissues, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006458fbdb887a687f4839167f5fbcff
https://doi.org/10.1523/jneurosci.1659-21.2021
https://doi.org/10.1523/jneurosci.1659-21.2021
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Amy Waldman, Ming Der Perng, Marzena Walkiewicz, Michael Brenner, Omar Sherbini, Guy Helman, Adeline Vanderver, Cas Simons, Sunetra Sase, Ling Zhao, Bret C. Haake, Zachary Cross, Sarah Woidill, Asako Takanohashi, Yangzhu Du, Ali Fatemi, Tracy L. Hagemann, Albee Messing
Publikováno v:
Hum Mutat
Alexander disease results from gain of function mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament protein expressed in astrocytes. At least eight GFAP isoforms have been described, however, the predominan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba83f47c608fd88cba4e2cd45d0be7c7
https://doi.org/10.1002/humu.24008
https://doi.org/10.1002/humu.24008
Autor:
Xue Fang, Henry E. Symons, Charl F. J. Faul, Maximilian J. L. Hagemann, Robert Stefan Wilson-Kovacs
Publikováno v:
Faul, C F J, Wilson-Kovacs, R S, Fang, X, Hagemann, M J L & Symons, H E 2022, ' Design and Control of Perylene Supramolecular Polymers through Imide Substitutions ', Chemistry – A European Journal, vol. 28, no. 3, e202103443 . https://doi.org/10.1002/chem.202103443
The number and type of new supramolecular polymer (SMP) systems have increased rapidly in recent years. Some of the key challenges faced for these novel systems include gaining full control over the mode of self-assembly, the creation of novel archit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe86cb3345a864eccd5770b51489cf5
https://hdl.handle.net/1983/ea9fa66c-0435-4caa-a4d3-2408f602e0ef
https://hdl.handle.net/1983/ea9fa66c-0435-4caa-a4d3-2408f602e0ef
