Zobrazeno 1 - 10 of 148 pro vyhledávání: '"L, Gaughan"'
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Akademický článek
Multidisciplinary neurosurgical rounds incorporating antimicrobial stewardship. Are they of benefit?
Autor: M. Creedon, H. Humphreys, R. Connolly, L. Gaughan, M. Skally, J. Caird, J. Duddy, P.J. O'Halloran, T. Mandiwanza, K. Burns, B. Dinesh, E. Smyth, K. O'Connell, F. Fitzpatrick
Publikováno v: Brain and Spine, Vol 2, Iss , Pp 100885- (2022)
Background: In an era of increasing antimicrobial resistance, appropriate antimicrobials are essential to optimise patient outcomes. In 2017, antimicrobial use prevalence (AMU) on the two neurosurgical wards in our tertiary teaching hospital varied f
Externí odkaz: https://doaj.org/article/e0a3b53add9a41d094d7ba2afc00506f
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2
Akademický článek
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3
Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study
Autor: Burtness, B. Harrington, K.J. Greil, R. Soulières, D. Tahara, M. de Castro, G., Jr Psyrri, A. Basté, N. Neupane, P. Bratland, Å. Fuereder, T. Hughes, B.G.M. Mesía, R. Ngamphaiboon, N. Rordorf, T. Wan Ishak, W.Z. Hong, R.-L. González Mendoza, R. Roy, A. Zhang, Y. Gumuscu, B. Cheng, J.D. Jin, F. Rischin, D. Lerzo, G. Tatangelo, M. Varela, M. Zarba, J.J. Boyer, M. Gan, H. Gao, B. Hughes, B. Mallesara, G. Taylor, A. Burian, M. Barrios, C.H. de Castro Junior, D.O. Castro, G. Franke, F.A. Girotto, G. Lima, I.P.F. Nicolau, U.R. Pinto, G.D.J. Santos, L. Victorino, A.-P. Chua, N. Couture, F. Gregg, R. Hansen, A. Hilton, J. McCarthy, J. Soulieres, D. Ascui, R. Gonzalez, P. Villanueva, L. Torregroza, M. Zambrano, A. Holeckova, P. Kral, Z. Melichar, B. Prausova, J. Vosmik, M. Andersen, M. Gyldenkerne, N. Jurgens, H. Putnik, K. Reinikainen, P. Gruenwald, V. Laban, S. Aravantinos, G. Boukovinas, I. Georgoulias, V. Kwong, D. Al-Farhat, Y. Csoszi, T. Erfan, J. Horvai, G. Landherr, L. Remenar, E. Ruzsa, A. Szota, J. Billan, S. Gluck, I. Gutfeld, O. Popovtzer, A. Benasso, M. Bui, S. Ferrari, V. Licitra, L. Nole, F. Fujii, T. Fujimoto, Y. Hanai, N. Hara, H. Matsumoto, K. Mitsugi, K. Monden, N. Nakayama, M. Okami, K. Oridate, N. Shiga, K. Shimizu, Y. Sugasawa, M. Takahashi, M. Takahashi, S. Tanaka, K. Ueda, T. Yamaguchi, H. Yamazaki, T. Yasumatsu, R. Yokota, T. Yoshizaki, T. Kudaba, I. Stara, Z. Cheah, S.K. Aguilar Ponce, J. Gonzalez Mendoza, R. Hernandez Hernandez, C. Medina Soto, F. Buter, J. Hoeben, A. Oosting, S. Suijkerbuijk, K. Bratland, A. Brydoey, M. Alvarez, R. Mas, L. Caguioa, P. Querol, J. Regala, E.E. Tamayo, M.B. Villegas, E.M. Kawecki, A. Karpenko, A. Klochikhin, A. Smolin, A. Zarubenkov, O. Goh, B.C. Cohen, G. du Toit, J. Jordaan, C. Landers, G. Ruff, P. Szpak, W. Tabane, N. Brana, I. Iglesias Docampo, L. Lavernia, J. Mesia, R. Abel, E. Muratidu, V. Nielsen, N. Cristina, V. Rothschild, S. Wang, H.-M. Yang, M.-H. Yeh, S.-P. Yen, C.-J. Soparattanapaisarn, N. Sriuranpong, V. Aksoy, S. Cicin, I. Ekenel, M. Harputluoglu, H. Ozyilkan, O. Agarwala, S. Ali, H. Alter, R. Anderson, D. Bruce, J. Campbell, N. Conde, M. Deeken, J. Edenfield, W. Feldman, L. Gaughan, E. Goueli, B. Halmos, B. Hegde, U. Hunis, B. Jotte, R. Karnad, A. Khan, S. Laudi, N. Laux, D. Martincic, D. McCune, S. McGaughey, D. Misiukiewicz, K. Mulford, D. Nadler, E. Nunnink, J. Ohr, J. O'Malley, M. Patson, B. Paul, D. Popa, E. Powell, S. Redman, R. Rella, V. Rocha Lima, C. Sivapiragasam, A. Su, Y. Sukari, A. Wong, S. Yilmaz, E. Yorio, J.
Background: Pembrolizumab is active in head and neck squamous cell carcinoma (HNSCC), with programmed cell death ligand 1 (PD-L1) expression associated with improved response. Methods: KEYNOTE-048 was a randomised, phase 3 study of participants with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::25cb1f03a8d1b22885303ced3a20f10f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121788
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4
Akademický článek
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5
The present state of the art in expression, production and characterization of monoclonal antibodies
Autor: Christopher L. Gaughan
Publikováno v: Molecular Diversity. 20:255-270
Monoclonal antibodies (MAb's) have become one the most powerful therapeutic and diagnostic tools in modern medicine. Some estimates target the worldwide market of MAb's on the order of $125 billion in the next four years. Recent advances in molecular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54993da102edda71b1cafde634d81134
https://doi.org/10.1007/s11030-015-9625-z
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6
Akademický článek
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7
In Vivo and In Vitro Effects of Acrylamide on Synaptosomal Neurotransmitter Uptake and Release
Autor: Richard M. LoPachin, Christopher L. Gaughan, Soma Das, Shirley Mansukhani, Aron I Schwarcz
Publikováno v: NeuroToxicology. 25:349-363
Evidence suggests acrylamide (ACR) neurotoxicity is mediated by impaired presynaptic transmission. To assess the effects of ACR on nerve terminal function, [3H] glutamate release and uptake were determined in brain synaptosomes isolated from intoxica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e872a9783bc17cf5d44c08fb32e16fd4
https://doi.org/10.1016/s0161-813x(03)00149-9
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8
Experimental Spinal Cord Injury: Spatiotemporal Characterization of Elemental Concentrations and Water Contents in Axons and Neuroglia
Autor: Thomas M. Kelly, Christopher L. Gaughan, Richard M. LoPachin, Andrew R. Blight, Ellen J. Lehning, Yoshiro Kaneko
Publikováno v: Journal of Neurophysiology. 82:2143-2153
To examine the role of axonal ion deregulation in acute spinal cord injury (SCI), white matter strips from guinea pig spinal cord were incubated in vitro and were subjected to graded focal compression injury. At several postinjury times, spinal segme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7953aecb49035286741d39ee37c2a98a
https://doi.org/10.1152/jn.1999.82.5.2143
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10
Electron probe x-ray microanalysis: a quantitative electron microscopy technique for measurement of elements and water in nervous tissue cells
Autor: R M, Lopachin, C L, Gaughan
Publikováno v: Methods in molecular medicine. 22
Although structure and function of the major cells comprising nervous tissue have been studied extensively, very little detailed information exists concerning subcellular distributions of water and such elements as Na, K, Cl, and Ca. This information
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::098640303a528acc1dfc54a6371bc7b8
https://pubmed.ncbi.nlm.nih.gov/21380843
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