Zobrazeno 1 - 10
of 1 764
pro vyhledávání: '"L, Franklin"'
Autor:
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 17-31 (2024)
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological s
Externí odkaz:
https://doaj.org/article/0149ce03e8b64eb8b051c0b241d31077
Autor:
Lydia Teboul, James Amos-Landgraf, Fernando J. Benavides, Marie-Christine Birling, Steve D. M. Brown, Elizabeth Bryda, Rosie Bunton-Stasyshyn, Hsian-Jean Chin, Martina Crispo, Fabien Delerue, Michael Dobbie, Craig L. Franklin, Ernst-Martin Fuchtbauer, Xiang Gao, Christelle Golzio, Rebecca Haffner, Yann Hérault, Martin Hrabe de Angelis, Kevin C. Kent Lloyd, Terry R. Magnuson, Lluis Montoliu, Stephen A. Murray, Ki-Hoan Nam, Lauryl M. J. Nutter, Eric Pailhoux, Fernando Pardo Manuel de Villena, Kevin Peterson, Laura Reinholdt, Radislav Sedlacek, Je Kyung Seong, Toshihiko Shiroishi, Cynthia Smith, Toru Takeo, Louise Tinsley, Jean-Luc Vilotte, Søren Warming, Sara Wells, C. Bruce Whitelaw, Atsushi Yoshiki, Asian Mouse Mutagenesis Resource Association, CELPHEDIA infrastructure, INFRAFRONTIER consortium, International Mammalian Genome Society, International Mouse Phenotyping Consortium, International Society for Transgenic Technologies, Mutant Mouse Resource and Research Centers, Phenomics Australia, RRRC- Rat Resource and Research Center, Guillaume Pavlovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract The biomedical research community addresses reproducibility challenges in animal studies through standardized nomenclature, improved experimental design, transparent reporting, data sharing, and centralized repositories. The ARRIVE guideline
Externí odkaz:
https://doaj.org/article/81e4d92fe0424d7c9017a0c563ae6724
Autor:
Nalin H. Maniya, Sonu Kumar, Jeffrey L. Franklin, James N. Higginbotham, Andrew M. Scott, Hui K. Gan, Robert J. Coffey, Satyajyoti Senapati, Hsueh-Chia Chang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract We present a quantitative sandwich immunoassay for CD63 Extracellular Vesicles (EVs) and a constituent surface cargo, EGFR and its activity state, that provides a sensitive, selective, fluorophore-free and rapid alternative to current EV-bas
Externí odkaz:
https://doaj.org/article/73f922b965a546b2a477dcf2d44e21d8
5‐Fluorouracil treatment represses pseudouridine‐containing miRNA export into extracellular vesicles
Autor:
Shimian Qu, Hannah M. Nelson, Xiao Liu, Yu Wang, Elizabeth M. Semler, Danielle L. Michell, Clark Massick, Jeffrey L. Franklin, John Karijolich, Alissa M. Weaver, Robert J. Coffey, Qi Liu, Kasey C. Vickers, James G. Patton
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract 5‐Fluorouracil (5‐FU) has been used for chemotherapy for colorectal and other cancers for over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine synthase leading to defects in DNA replication and repair.
Externí odkaz:
https://doaj.org/article/6e5702c671f04d8e9a2013298d18c044
Autor:
James Kim, Shihan Xu, Seung‐Ryoung Jung, Alya Nguyen, Yuanhua Cheng, Mengxia Zhao, Bryant S. Fujimoto, Wyatt Nelson, Perry Schiro, Jeffrey L. Franklin, James N. Higginbotham, Robert J. Coffey, Min Shi, Lucia N. Vojtech, Florian Hladik, Muneesh Tewari, John Tigges, Ionita Ghiran, Tijana Jovanovic‐Talisman, Louise C. Laurent, Saumya Das, Olesia Gololobova, Kenneth W. Witwer, Tuoye Xu, Al Charest, Kendall Van Keuren Jensen, Robert L. Raffai, Jennifer C. Jones, Joshua A. Welsh, John P. Nolan, Daniel T. Chiu
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract High‐sensitivity flow cytometers have been developed for multi‐parameter characterization of single extracellular vesicles (EVs), but performance varies among instruments and calibration methods. Here we compare the characterization of i
Externí odkaz:
https://doaj.org/article/7ea6b425e4f14da5b65bb5379df9a944
Autor:
Amber L. Russell, Zachary L. McAdams, Erin Donovan, Nicole Seilhamer, Melissa Siegrist, Craig L. Franklin, Aaron C. Ericsson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract There is limited understanding of how the microbiota colonizing various maternal tissues contribute to the development of the neonatal gut microbiota (GM). To determine the contribution of various maternal microbiotic sites to the offspring
Externí odkaz:
https://doaj.org/article/80d57c6a01e845dd82104809f02318a7
Autor:
A. Torres-Freyermuth, G. Medellín, J. A. Kurczyn, R. Pacheco-Castro, J. Arriaga, C. M. Appendini, M. E. Allende-Arandía, J. A. Gómez, G. L. Franklin, J. Zavala-Hidalgo
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 22, Pp 4063-4085 (2022)
Barrier islands in tropical regions are prone to coastal flooding and erosion during hurricane events. The Yucatán coast, characterized by karstic geology and the presence of barrier islands, was impacted by Hurricane Gamma and Hurricane Delta in Oc
Externí odkaz:
https://doaj.org/article/b38f91323ce4437ca843acbf74c18b1b
Autor:
Chenguang Zhang, Xiaoye Huo, Yini Zhu, James N. Higginbotham, Zheng Cao, Xin Lu, Jeffrey L. Franklin, Kasey C. Vickers, Robert J. Coffey, Satyajyoti Senapati, Ceming Wang, Hsueh-Chia Chang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
A magnetic nanoporous membrane is engineered for immunocapture of extracellular vesicles and lipoproteins in heterogeneous physiological fluids, such as plasma and saliva, and quantification of cargo and biomarkers in these nanocarriers.
Externí odkaz:
https://doaj.org/article/18353056538849a099f70b57d61adaa9
Autor:
Chunye Zhang, Yushu Shi, Matthew Burch, Benjamin Olthoff, Aaron C. Ericsson, Craig L. Franklin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract To test causal relationships between complex gut microbiota (GM) and host outcomes, researchers frequently transfer GM between donor and recipient mice via embryo transfer (ET) rederivation, cross-fostering (CF), and co-housing. In this stud
Externí odkaz:
https://doaj.org/article/e5c486b44ca74b9a85af76d39a7d9afe
Autor:
Alex T. Meira, Jorge E. D. Araruna, Lais Vieira Araujo, Raíssa N. L. F. Leite, Gustavo L. Franklin, Adriana M. T. Nepomuceno, Hélio A. G. Teive
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 81, Iss 11, Pp 1018-1019 (2023)
Externí odkaz:
https://doaj.org/article/e507ec2af56749ebba4932242fed9c57