Zobrazeno 1 - 10
of 360
pro vyhledávání: '"L, Eckhardt"'
Autor:
Corey L. Anderson, Emma R. Langer, Timothy C. Routes, Seamus F. McWilliams, Igor Bereslavskyy, Timothy J. Kamp, Lee L. Eckhardt
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Hundreds of LMNA variants have been associated with several distinct disease phenotypes. However, genotype–phenotype relationships remain largely undefined and the impact for most variants remains unknown. We performed a functional analysi
Externí odkaz:
https://doaj.org/article/cb36d873da8841c288bf1a7f3c726247
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Disease modeling using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has both challenges and promise. While patient-derived iPSC-CMs provide a unique opportunity for disease modeling with isogenic cells, the challenge is that
Externí odkaz:
https://doaj.org/article/9d886bda78ea473a802fa1842052c92b
Autor:
Corey L. Anderson, Saba Munawar, Louise Reilly, Timothy J. Kamp, Craig T. January, Brian P. Delisle, Lee L. Eckhardt
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Over the last two decades, an exponentially expanding number of genetic variants have been identified associated with inherited cardiac conditions. These tremendous gains also present challenges in deciphering the clinical relevance of unclassified v
Externí odkaz:
https://doaj.org/article/ae94dfc1a53e416cbf25d2dfb342f9e2
Autor:
Lee L. Eckhardt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/4cee683f04ca4e45a561a70a96b3eeb0
Autor:
A. Stempien, M. Josvai, W. J. de Lange, J. J. Hernandez, J. Notbohm, T. J. Kamp, H. H. Valdivia, L. L. Eckhardt, K. R. Maginot, J. C. Ralphe, W. C. Crone
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by an arrhythmogenic mechanism involving disruption of calcium handling. This genetic disease can lead to sudden death in children and young adults during physical or emoti
Externí odkaz:
https://doaj.org/article/b52dc20a5f1c4b18b367119abcc30398
Autor:
Khaled Atmar, Claudia A. L. Ruivenkamp, Louise Hooimeijer, Esther A. R. Nibbeling, Corien L. Eckhardt, Elise J. Huisman, Arjan C. Lankester, Marije Bartels, Gijs W. E. Santen, Frans J. Smiers, Mirjam van der Burg, Alexander B. Mohseny
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundSevere multilineage cytopenia in childhood caused by bone marrow failure (BMF) often represents a serious condition requiring specific management. Patients are at risk for invasive infections and bleeding complications. Previous studies rep
Externí odkaz:
https://doaj.org/article/021d8bd9944845ca8c30ccf0647fa945
Publikováno v:
Heart & Lung. 61:98-106
Autor:
Jens Cosedis Nielsen, Yenn‐Jiang Lin, Marcio Jansen de Oliveira Figueiredo, Alireza Sepehri Shamloo, Alberto Alfie, Serge Boveda, Nikolaos Dagres, Dario Di Toro, Lee L. Eckhardt, Kenneth Ellenbogen, Carina Hardy, Takanori Ikeda, Aparna Jaswal, Elizabeth Kaufman, Andrew Krahn, Kengo Kusano, Valentina Kutyifa, Han S. Lim, Gregory Y. H. Lip, Santiago Nava‐Townsend, Hui‐Nam Pak, Gerardo Rodríguez Diez, William Sauer, Anil Saxena, Jesper Hastrup Svendsen, Diego Vanegas, Marmar Vaseghi, Arthur Wilde, T. Jared Bunch
Publikováno v:
Journal of Arrhythmia, Vol 36, Iss 4, Pp 553-607 (2020)
Externí odkaz:
https://doaj.org/article/6cd098381cb64e73a13bd385d12a88f1
Autor:
Peter M. Kekenes-Huskey, Don E. Burgess, Bin Sun, Daniel C. Bartos, Ezekiel R. Rozmus, Corey L. Anderson, Craig T. January, Lee L. Eckhardt, Brian P. Delisle
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7389 (2022)
The electrocardiogram (ECG) empowered clinician scientists to measure the electrical activity of the heart noninvasively to identify arrhythmias and heart disease. Shortly after the standardization of the 12-lead ECG for the diagnosis of heart diseas
Externí odkaz:
https://doaj.org/article/b854c6681c334712a3b75b03eb578b77
Autor:
Yogananda S. Markandeya, Zachery R. Gregorich, Li Feng, Vignesh Ramchandran, Thomas O' Hara, Ravi Vaidyanathan, Catherine Mansfield, Alexis M. Keefe, Carl J. Beglinger, Jabe M. Best, Matthew M. Kalscheur, Martin R. Lea, Timothy A. Hacker, Julia Gorelik, Natalia A. Trayanova, Lee L. Eckhardt, Jonathan C. Makielski, Ravi C. Balijepalli, Timothy J. Kamp
Publikováno v:
Journal of Molecular and Cellular Cardiology. 177:38-49