Zobrazeno 1 - 10
of 1 309
pro vyhledávání: '"L, Dumont"'
Autor:
Ashira Lubkin, Lucie Bernard-Raichon, Ashley L. DuMont, Ana Mayela Valero Jimenez, Gregory G. Putzel, Juan Gago, Erin E. Zwack, Olufolakemi Olusanya, Kristina M. Boguslawski, Simone Dallari, Sophie Dyzenhaus, Christin Herrmann, Juliana K. Ilmain, Georgia L. Isom, Miranda Pawline, Andrew I. Perault, Sofya Perelman, William E. Sause, Ifrah Shahi, Amelia St. John, Rebecca Tierce, Xuhui Zheng, Chunyi Zhou, Maria G. Noval, Anna O'Keeffe, Magda Podkowik, Sandra Gonzales, Kenneth Inglima, Ludovic Desvignes, Sarah E. Hochman, Kenneth A. Stapleford, Lorna E. Thorpe, Alejandro Pironti, Bo Shopsin, Ken Cadwell, Meike Dittmann, Victor J. Torres
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Severe COVID-19 has been associated with coinfections with bacterial and fungal pathogens. Notably, patients with COVID-19 who develop Staphylococcus aureus bacteremia exhibit higher rates of mortality than those infected with either pathoge
Externí odkaz:
https://doaj.org/article/623845162cdd4f2baf78452f589aa583
Autor:
Magdalena Podkowik, Andrew I Perault, Gregory Putzel, Andrew Pountain, Jisun Kim, Ashley L DuMont, Erin E Zwack, Robert J Ulrich, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin
Publikováno v:
eLife, Vol 12 (2024)
The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H2O2, a crucial host defense against S. aureus. We now report that protection by a
Externí odkaz:
https://doaj.org/article/c264dee56d4048e58f3b62b5d7161394
Autor:
Beth L Dumont, Daniel M Gatti, Mallory A Ballinger, Dana Lin, Megan Phifer-Rixey, Michael J Sheehan, Taichi A Suzuki, Lydia K Wooldridge, Hilda Opoku Frempong, Raman Akinyanju Lawal, Gary A Churchill, Cathleen Lutz, Nadia Rosenthal, Jacqueline K White, Michael W Nachman
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011228 (2024)
The laboratory mouse has served as the premier animal model system for both basic and preclinical investigations for over a century. However, laboratory mice capture only a subset of the genetic variation found in wild mouse populations, ultimately l
Externí odkaz:
https://doaj.org/article/056cd0f35c8645fd9c7518b7d3164020
Autor:
Zachary J. Williams, Roseann Schaaf, Karla K. Ausderau, Grace T. Baranek, D. Jonah Barrett, Carissa J. Cascio, Rachel L. Dumont, Ekomobong E. Eyoh, Michelle D. Failla, Jacob I. Feldman, Jennifer H. Foss-Feig, Heather L. Green, Shulamite A. Green, Jason L. He, Elizabeth A. Kaplan-Kahn, Bahar Keçeli-Kaysılı, Keren MacLennan, Zoe Mailloux, Elysa J. Marco, Lisa E. Mash, Elizabeth P. McKernan, Sophie Molholm, Stewart H. Mostofsky, Nicolaas A. J. Puts, Caroline E. Robertson, Natalie Russo, Nicole Shea, John Sideris, James S. Sutcliffe, Teresa Tavassoli, Mark T. Wallace, Ericka L. Wodka, Tiffany G. Woynaroski
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-28 (2023)
Abstract Background Differences in responding to sensory stimuli, including sensory hyperreactivity (HYPER), hyporeactivity (HYPO), and sensory seeking (SEEK) have been observed in autistic individuals across sensory modalities, but few studies have
Externí odkaz:
https://doaj.org/article/dea0fb5adbdd44caa46eddfb2fb73bfc
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113178- (2023)
Summary: Centromeres are crucial for chromosome segregation, but their underlying sequences evolve rapidly, imposing strong selection for compensatory changes in centromere-associated kinetochore proteins to assure the stability of genome transmissio
Externí odkaz:
https://doaj.org/article/d7713c1ce6394892850c00157582d497
Autor:
Raman Akinyanju Lawal, Verity L. Mathis, Mary E. Barter, Jeremy R. Charette, Alexis Garretson, Beth L. Dumont
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The house mouse species complex (Mus musculus) is comprised of three primary subspecies. A large number of secondary subspecies have also been suggested on the basis of divergent morphology and molecular variation at limited numbers of marke
Externí odkaz:
https://doaj.org/article/dbc9ba06c3ca46de839ef9e8efa6445e
Autor:
Benjamin L. Dumont, Paul-Eduard Neagoe, Elcha Charles, Louis Villeneuve, Jean-Claude Tardif, Agnès Räkel, Michel White, Martin G. Sirois
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1674 (2024)
Type 2 diabetes (T2D) is characterized by low-grade inflammation. Low-density neutrophils (LDNs) represent normally less than 2% of total neutrophils but increase in multiple pathologies, releasing inflammatory cytokines and neutrophil extracellular
Externí odkaz:
https://doaj.org/article/cdceb70ab3b9441b86d2e28c038043f4
Autor:
Alaina S. Berruti, Roseann C. Schaaf, Emily A. Jones, Elizabeth Ridgway, Rachel L. Dumont, Benjamin Leiby, Catherine Sancimino, Misung Yi, Sophie Molholm
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The COVID-19 pandemic impacted nearly all facets of our daily lives, and clinical research was no exception. Here, we discuss the impact of the pandemic on our ongoing, three-arm randomized controlled trial (RCT) Sensory Integrati
Externí odkaz:
https://doaj.org/article/b172b62c3e674b1394db11b23ebc659a
Autor:
Amelia St. John, Andrew I. Perault, Sabrina I. Giacometti, Alexis G. Sommerfield, Ashley L. DuMont, Keenan A. Lacey, Xuhui Zheng, Julia Sproch, Chris Petzold, Kristen Dancel-Manning, Sandra Gonzalez, Medini Annavajhala, Colleen Beckford, Nathalie Zeitouni, Feng-Xia Liang, Harm van Bakel, Bo Shopsin, Anne-Catrin Uhlemann, Alejandro Pironti, Victor J. Torres
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Nosocomial infections caused by multidrug-resistant (MDR) Enterobacter cloacae complex (ECC) pathogens are on the rise. However, the virulence strategies employed by these pathogens remain elusive. Here, we study the interaction of ECC clini
Externí odkaz:
https://doaj.org/article/d3aff886dd104f129b126519af1d6e50
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Through human-aided dispersal over the last ~ 10,000 years, house mice (Mus musculus) have recently colonized diverse habitats across the globe, promoting the emergence of new traits that confer adaptive advantages in distinct env
Externí odkaz:
https://doaj.org/article/1fa154a03aad4ba0917fffda86161afb