Zobrazeno 1 - 10
of 977
pro vyhledávání: '"L, Clayton"'
Autor:
Emily Kawabata, Daniel Major-Smith, Gemma L. Clayton, Chin Yang Shapland, Tim P. Morris, Alice R. Carter, Alba Fernández-Sanlés, Maria Carolina Borges, Kate Tilling, Gareth J. Griffith, Louise A. C. Millard, George Davey Smith, Deborah A. Lawlor, Rachael A. Hughes
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Bias from data missing not at random (MNAR) is a persistent concern in health-related research. A bias analysis quantitatively assesses how conclusions change under different assumptions about missingness using bias parameters tha
Externí odkaz:
https://doaj.org/article/bff0a04323cc4ded81d4e12595170e9c
Autor:
Jordana L. Clayton, Rebecca L. Utz, Nancy Aruscavage, Sara G. Bybee, Sharon E. Bigger, Eli Iacob, Kara B. Dassel
Publikováno v:
Contemporary Clinical Trials Communications, Vol 42, Iss , Pp 101398- (2024)
Community engagement is increasingly considered a key component of intervention development, as it can leverage community members’ knowledge, experiences, and insights to create a nuanced intervention which meets the needs, preferences, and realiti
Externí odkaz:
https://doaj.org/article/b3ba490fd60a490e84994c111f8f544d
Autor:
Ahmed Elhakeem, Gemma L. Clayton, Ana Goncalves Soares, Kurt Taylor, Léa Maitre, Gillian Santorelli, John Wright, Deborah A. Lawlor, Martine Vrijheid
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Lower socioeconomic position (SEP) associates with adverse pregnancy and perinatal outcomes and with less favourable metabolic profile in nonpregnant adults. Socioeconomic differences in pregnancy metabolic profile are unknown. We
Externí odkaz:
https://doaj.org/article/2d44ea3d85e146d1a510ea7740f1824d
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract We explore the relation between age at menarche, parity and age at natural menopause with 249 metabolic traits in over 65,000 UK Biobank women using multivariable regression, Mendelian randomization and negative control (parity only). Older
Externí odkaz:
https://doaj.org/article/ed9e48554ac646949838851d3c4938e0
Autor:
Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Higher maternal pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and perinatal outcomes. However, whether these associations are causal remains unclear. Methods We explored the relation of maternal pre-/ear
Externí odkaz:
https://doaj.org/article/0a4789dc4d5f4384bda3a38300dc1bb0
Autor:
Grant C. Weaver, Christine L. Schneider, Aniuska Becerra-Artiles, Kiera L. Clayton, Amy W. Hudson, Lawrence J. Stern
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman Herpesvirus 6B (HHV-6B) impedes host immune responses by downregulating class I MHC molecules (MHC-I), hindering antigen presentation to CD8+ T cells. Downregulation of MHC-I disengages inhibitory receptors on natural killer (NK) ce
Externí odkaz:
https://doaj.org/article/b3e8081e247a4c37bd1498def231db06
Autor:
Bridgette J. McNamara, Kim R. Blasdell, Arvind Yerramilli, Ina L. Smith, Simone L. Clayton, Michael Dunn, Ee Laine Tay, Katherine B. Gibney, Nilakshi T. Waidyatillake, Mohammad A. Hussain, Michael Muleme, Daniel P. O’Brien, Eugene Athan
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2032-2043 (2023)
To examine protective and risk factors for Buruli ulcer (BU), we conducted a case–control study of 245 adult BU cases and 481 postcode-matched controls across BU-endemic areas of Victoria, Australia. We calculated age- and sex-adjusted odds ratios
Externí odkaz:
https://doaj.org/article/9ea54c69fdfa400a99520492e7ebacc1
Autor:
Alice R Carter, Gemma L Clayton, M Carolina Borges, Laura D Howe, Rachael A Hughes, George Davey Smith, Deborah A Lawlor, Kate Tilling, Gareth J Griffith
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background There are many ways in which selection bias might impact COVID-19 research. Here we focus on selection for receiving a polymerase-chain-reaction (PCR) SARS-CoV-2 test and how known changes to selection pressures over time may bias
Externí odkaz:
https://doaj.org/article/bebc88621a264ddb8f00bf0f3c4057aa
Autor:
Fanny Kilpi, Ana Goncalves Soares, Gemma L. Clayton, Abigail Fraser, Paul Welsh, Naveed Sattar, Scott M. Nelson, Kate Tilling, Deborah A. Lawlor
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Whether women’s physical function in mid-life is related to their reproductive age is not known. The objectives of this study were to examine and compare changes in physical function in women by reproductive age, measured as tim
Externí odkaz:
https://doaj.org/article/7253c3d83a384174b1e88cc7f7f1f3ea
Autor:
Gemma L. Clayton, Ana Gonçalves Soares, Fanny Kilpi, Abigail Fraser, Paul Welsh, Naveed Sattar, Scott M. Nelson, Kate Tilling, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Women experience adverse changes in cardiovascular health in mid-life; whether the menopausal transition influences these remains strongly debated. The aim of this study was to examine associations of reproductive age (time since
Externí odkaz:
https://doaj.org/article/cbcd4b17b0e54ff58033cb7199b3949a