Zobrazeno 1 - 10
of 267
pro vyhledávání: '"L, Cellai"'
Autor:
Savino Sciascia, Dario Roccatello, Marco Salvatore, Claudio Carta, Laura L. Cellai, Gianluca Ferrari, Aimè Lumaka, Stephen Groft, Yasemin Alanay, Maleeha Azam, Gareth Baynam, Helene Cederroth, Eva Maria Cutiongco-de la Paz, Vajira Harshadeva Weerabaddana Dissanayake, Roberto Giugliani, Claudia Gonzaga-Jauregui, Dineshani Hettiarachchi, Oleg Kvlividze, Guida Landoure, Prince Makay, Béla Melegh, Ugur Ozbek, Ratna Dua Puri, Vanessa I. Romero, Vinod Scaria, Saumya S. Jamuar, Vorasuk Shotelersuk, William A. Gahl, Samuel A. Wiafe, Olaf Bodamer, Manuel Posada, Domenica Taruscio
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundPatients, families, the healthcare system, and society as a whole are all significantly impacted by rare diseases (RDs). According to various classifications, there are currently up to 9,000 different rare diseases that have been recognized
Externí odkaz:
https://doaj.org/article/da71af76c6954864ad49d713a5a8c259
Autor:
Domenica Taruscio, Marco Salvatore, Aimè Lumaka, Claudio Carta, Laura L. Cellai, Gianluca Ferrari, Savino Sciascia, Stephen Groft, Yasemin Alanay, Maleeha Azam, Gareth Baynam, Helene Cederroth, Eva Maria Cutiongco-de la Paz, Vajira Harshadeva Weerabaddana Dissanayake, Roberto Giugliani, Claudia Gonzaga-Jauregui, Dineshani Hettiarachchi, Oleg Kvlividze, Guida Landoure, Prince Makay, Béla Melegh, Ugur Ozbek, Ratna Dua Puri, Vanessa Romero, Vinod Scaria, Saumya S. Jamuar, Vorasuk Shotelersuk, Dario Roccatello, William A. Gahl, Samuel A. Wiafe, Olaf Bodamer, Manuel Posada
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionRare diseases (RD) are a health priority worldwide, overall affecting hundreds of millions of people globally. Early and accurate diagnosis is essential to support clinical care but remains challenging in many countries, especially the lo
Externí odkaz:
https://doaj.org/article/2227df40187d4d7eabf002601c80d926
Autor:
Rosaria A Cavallaro, Cinzia Marianelli, Giuseppe Mascellani, Antonino Di Caro, Giuseppina La Rosa, Lino Liverani, Michele Muscillo, Barbara Bartolini, Arrigo Benedetto, L. Cellai
Publikováno v:
Antiviral Research. 58:139-147
In the search for new drugs against human immunodeficiency virus type 1 (HIV-1), the replication of III(B) and BaL strains, and of seven primary isolates from AIDS patients, cultured both in peripheral blood lymphocytes (PBLs) and in monocyte-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914c49b12a440abeda025460cf447ca3
https://doi.org/10.1016/s0166-3542(02)00209-7
https://doi.org/10.1016/s0166-3542(02)00209-7
Autor:
Ulrich Hübscher, Giuseppe Villani, E. Seeberg, Giovanni Maga, Barbara Pascucci, Ian D. Hickson, Magnar Bjørås, Cesare Giordano, L. Cellai, Eugenia Dogliotti
Publikováno v:
Scopus-Elsevier
Nucleic acids research (2002).
info:cnr-pdr/source/autori:Pascucci B, Maga G, Hübscher U, Bjoras M, Seeberg E, Hickson ID, Villani G, Giordano C, Cellai L, Dogliotti E./titolo:Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins./doi:/rivista:Nucleic acids research/anno:2002/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nucleic acids research (2002).
info:cnr-pdr/source/autori:Pascucci B, Maga G, Hübscher U, Bjoras M, Seeberg E, Hickson ID, Villani G, Giordano C, Cellai L, Dogliotti E./titolo:Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins./doi:/rivista:Nucleic acids research/anno:2002/pagina_da:/pagina_a:/intervallo_pagine:/volume
In mammalian cells, repair of the most abundant endogenous premutagenic lesion in DNA, 7,8-dihydro-8-oxoguanine (8-oxoG), is initiated by the bifunctional DNA glycosylase OGG1. By using purified human proteins, we have reconstituted repair of 8-oxoG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2ba87d14fd72074c9997d47e68492
https://doi.org/10.1093/nar/30.10.2124
https://doi.org/10.1093/nar/30.10.2124
Publikováno v:
Biochemistry. 38:5714-5719
The crystal structure of Torpedo californica (Tc) acetylcholinesterase (AChE) carbamoylated by the physostigmine analogue 8-(cis-2,6-dimethylmorpholino)octylcarbamoyleseroline (MF268) is reported at 2.7 A resolution. In the X-ray structure, the dimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38d58d47b3a7aa9b382b6ce418a26c0
https://doi.org/10.1021/bi982723p
https://doi.org/10.1021/bi982723p
Autor:
M. A. Iannelli, A. Margonelli, P. Ragni, M. C. Cesta, C. Sparapani, S. Lappa, Giancarlo Angelini, L. Cellai
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 39:747-756
The title myo-[1- 3 H]-Inositol derivative was synthesized and characterized by tritium-N.M.R.. The unlabelled compound proved a potent inhibitor of the cellular key enzyme phosphatidylinositol-specific phospholipase-C (Pl-PLC) involved in the produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cd6d1e33819b7c8eec55bbaf3f7293
https://doi.org/10.1002/(sici)1099-1344(199709)39:9<747::aid-jlcr16>3.0.co
https://doi.org/10.1002/(sici)1099-1344(199709)39:9<747::aid-jlcr16>3.0.co
Publikováno v:
Inflammation. 21:391-400
In our study we investigated the effect of rifamycin SV, rifamycin B, rifampicin and five semisynthetic derivatives on human neutrophil functions such as locomotion, superoxide production and degranulation stimulated by specific agonists. All compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24eaefbb5df1570c243dcdb3ab6599aa
https://doi.org/10.1023/a:1027314419843
https://doi.org/10.1023/a:1027314419843
Autor:
Concetta Martuccio, Simona Rizea Savu, Luigi Silvestro, C. Bartolucci, L. Cellai, Andrea Rossi, A. L. Segre
Publikováno v:
Helvetica Chimica Acta. 79:1611-1619
Glycosylrifamycins, a new type of semisynthetic rifamycin derivatives, can be easily obtained by reaction of 3-(2-aminoethylthio)rifamycin SV (2) with a glycosyl compound carrying a coupling group, such as isothicyanate or carboxy. We prepared O-acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1669dce7c49bb74994838ea4c3b2b3a
https://doi.org/10.1002/hlca.19960790611
https://doi.org/10.1002/hlca.19960790611
Inhibition of human leukocyte elastase by chemically and naturally oversulfated galactosaminoglycans
Autor:
Emanuele Perola, Giuseppe Mascellani, Maria Adelaide Iannelli, L. Cellai, Doriano Lamba, Lino Liverani, Cecilia Bartolucci
Publikováno v:
Carbohydrate Research. 276:401-408
Several samples of oversulfated chondroitin and dermatan were obtained by chemical sulfation and by SAX-HPLC enrichment. The starting products and oversulfated products were tested as potential inhibitors of human leukocyte elastase, an enzyme hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf55d4d1924b0e71c8ec6fc72f9c53
https://doi.org/10.1016/0008-6215(95)00179-w
https://doi.org/10.1016/0008-6215(95)00179-w
Autor:
E. Perola, Hans J. Gross, S. F. J. Le Grice, S. Fackler, Matthias Götte, Thomas Hermann, Hermann Heumann, L. Cellai
Publikováno v:
The EMBO Journal. 14:833-841
Reverse transcription of human immunodeficiency virus type 1 (HIV-1) is primed by tRNA(Lys3), which forms an 18 base pair RNA homoduplex with its 3' terminus and the primer binding site (PBS) of the viral genome. Using an in vitro system mimicking in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36c551f1f487eb5183bbd405cd7fb77
https://doi.org/10.1002/j.1460-2075.1995.tb07061.x
https://doi.org/10.1002/j.1460-2075.1995.tb07061.x