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Akademický článek

A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I.

Autor: Melissa Toledo, Xianfei Sun, Miguel A Brieño-Enríquez, Vandana Raghavan, Stephen Gray, Jeffrey Pea, Carolyn R Milano, Anita Venkatesh, Lekha Patel, Peter L Borst, Eric Alani, Paula E Cohen

Publikováno v: PLoS Genetics, Vol 15, Iss 6, p e1008177 (2019)

During meiotic prophase I, double-strand breaks (DSBs) initiate homologous recombination leading to non-crossovers (NCOs) and crossovers (COs). In mouse, 10% of DSBs are designated to become COs, primarily through a pathway dependent on the MLH1-MLH3

Externí odkaz: https://doaj.org/article/2301dc7578d3400e8f4d548e7998544d

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Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses

Autor: Stephanie B. H. Gumbs, Raphael Kübler, Lavina Gharu, Pauline J. Schipper, Anne L. Borst, Gijsje J. L. J. Snijders, Paul R. Ormel, Amber Berdenis van Berlekom, Annemarie M. J. Wensing, Lot D. de Witte, Monique Nijhuis

Publikováno v: Journal of NeuroVirology. 28:64-91

HIV persistence in the CNS despite antiretroviral therapy may cause neurological disorders and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected microglia, the main viral CNS reservoir, is imperative. Here, we pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e7d1f28e3c4d6879f5c796fc404a1c
https://doi.org/10.1007/s13365-021-01049-w

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Increasing the application of geothermal energy in the greenhouse sector: a case study from the Netherlands

Autor: L. Borst, N. Buik, M. van Dijk, W. van Leeuwen, E. Hollebeek

Publikováno v: First Break. 38:69-72

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ee053659405b98a594c068bff002b2
https://doi.org/10.3997/1365-2397.fb2020076

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A Comparison of Predicted and Actual Reservoir Quality of Geothermal Projects in the Slochteren Formation

Autor: N. Buik, W. van Leeuwen, L. Borst, N. Shaw

Publikováno v: 82nd EAGE Annual Conference & Exhibition.

Summary Now that four geothermal projects have successfully been completed in the Slochteren Formation, the formation has proven as a valid aquifer for geothermal heating purposes. Before drilling a project, the local reservoir parameters need to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2646b0ffc970e0689139e4e9a724c64f
https://doi.org/10.3997/2214-4609.202010460

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Akademický článek

Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis.

Autor: J Kim Holloway, Swapna Mohan, Gabriel Balmus, Xianfei Sun, Andrew Modzelewski, Peter L Borst, Raimundo Freire, Robert S Weiss, Paula E Cohen

Publikováno v: PLoS Genetics, Vol 7, Iss 6, p e1002094 (2011)

The mammalian ortholog of yeast Slx4, BTBD12, is an ATM substrate that functions as a scaffold for various DNA repair activities. Mutations of human BTBD12 have been reported in a new sub-type of Fanconi anemia patients. Recent studies have implicate

Externí odkaz: https://doaj.org/article/e443f7e8688f403396d4a63af1348e9b

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