Zobrazeno 1 - 10
of 1 653
pro vyhledávání: '"L, Avery"'
Autor:
Sairam Behera, Jonathan R. Belyeu, Xiao Chen, Luis F. Paulin, Ngoc Quynh H. Nguyen, Emma Newman, Medhat Mahmoud, Vipin K. Menon, Qibin Qi, Parag Joshi, Santica Marcovina, Massimiliano Rossi, Eric Roller, James Han, Vitor Onuchic, Christy L. Avery, Christie M. Ballantyne, Carlos J. Rodriguez, Robert C. Kaplan, Donna M. Muzny, Ginger A. Metcalf, Richard A. Gibbs, Bing Yu, Eric Boerwinkle, Michael A. Eberle, Fritz J. Sedlazeck
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract The abundance of Lp(a) protein holds significant implications for the risk of cardiovascular disease (CVD), which is directly impacted by the copy number (CN) of KIV-2, a 5.5 kbp sub-region. KIV-2 is highly polymorphic in the population and
Externí odkaz:
https://doaj.org/article/b08e11c0c6a64b4e840870232441e2bd
Autor:
Jessica I. Lundin, Ulrike Peters, Yao Hu, Farah Ammous, Christy L. Avery, Emelia J. Benjamin, Joshua C. Bis, Jennifer A. Brody, Chris Carlson, Mary Cushman, Chris Gignoux, Xiuqing Guo, Jeff Haessler, Chris Haiman, Roby Joehanes, Silva Kasela, Eimear Kenny, Tuuli Lapalainien, Daniel Levy, Chunyu Liu, Yongmei Liu, Ruth J.F. Loos, Ake Lu, Tara Matise, Kari E. North, Sungshim L. Park, Scott M. Ratliff, Alex Reiner, Stephen S. Rich, Jerome I. Rotter, Jennifer A. Smith, Nona Sotoodehnia, Russell Tracy, David Van den Berg, Huichun Xu, Ting Ye, Wei Zhao, Laura M. Raffield, Charles Kooperberg
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTSystemic low-grade inflammation is a feature of chronic disease. C-reactive protein (CRP) is a common biomarker of inflammation and used as an indicator of disease risk; however, the role of inflammation in disease is not completely understoo
Externí odkaz:
https://doaj.org/article/f6942193d47e4a7095b9b17d360571e0
Autor:
Yilun Li, Kin Yau Wong, Annie Green Howard, Penny Gordon-Larsen, Heather M. Highland, Mariaelisa Graff, Kari E. North, Carolina G. Downie, Christy L. Avery, Bing Yu, Kristin L. Young, Victoria L. Buchanan, Robert Kaplan, Lifang Hou, Brian Thomas Joyce, Qibin Qi, Tamar Sofer, Jee-Young Moon, Dan-Yu Lin
Publikováno v:
HGG Advances, Vol 5, Iss 4, Pp 100338- (2024)
Summary: Multivariable Mendelian randomization allows simultaneous estimation of direct causal effects of multiple exposure variables on an outcome. When the exposure variables of interest are quantitative omic features, obtaining complete data can b
Externí odkaz:
https://doaj.org/article/5171015866ab400cb3f6deffca141767
Publikováno v:
Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Background Surgical trials are recognised as inherently challenging. Pilot and feasibility studies (PAFS) are increasingly acknowledged as a key method to optimise the design and conduct of randomised trials but remain limited in surgery. We
Externí odkaz:
https://doaj.org/article/314c45b318f34127b7cfa26f3f4169d8
Autor:
Sarah M. Frank, Lindsay M Jaacks, Katie Meyer, Donald Rose, Linda S Adair, Christy L Avery, Lindsey Smith Taillie
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background The Planetary Health Diet Index (PHDI) measures adherence to the dietary pattern presented by the EAT-Lancet Commission, which aligns health and sustainability targets. There is a need to understand how PHDI scores correlate with
Externí odkaz:
https://doaj.org/article/1b241bff00034a92845bafa9384b3f3c
Publikováno v:
International Journal of Emergency Medicine, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract In 2021, a large urban university-based hospital transitioned to a new two-floor emergency department. Despite the new environment, there were usability and workflow challenges with the space. The authors of this paper created a multidiscipl
Externí odkaz:
https://doaj.org/article/9cfacd414dee4d69a2d2a3997b9eb40c
Autor:
Christy L. Avery, Annie Green Howard, Harold H. Lee, Carolina G. Downie, Moa P. Lee, Sarah H. Koenigsberg, Anna F. Ballou, Michael H. Preuss, Laura M. Raffield, Rina A. Yarosh, Kari E. North, Penny Gordon-Larsen, Mariaelisa Graff
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-8 (2023)
Abstract Background The branched chain amino acids (BCAA) leucine, isoleucine, and valine are essential nutrients that have been associated with diabetes, cancers, and cardiovascular diseases. Observational studies suggest that BCAAs exert homogeneou
Externí odkaz:
https://doaj.org/article/33a3c57423f141d8b3603098fa178114
Autor:
Leila Rooshenas, Jane M Blazeby, Angus G K McNair, Michael R Whitehouse, Christie Cabral, Jessica Preshaw, Barnaby Reeves, Shelley Potter, Kerry N L Avery, Philip Braude, Adam Williams, Ben Gibbison, Jennifer Hall, Andy Judge, Hilary L Bekker, Jonathan Aning, Rhiannon C Macefield, Christin Hoffmann, Val Snelgrove, Della Hopkins, Shireen Hickey, Archana Lingampalli, Paul Cresswell, Timothy Beckitt, Timothy Whittlestone
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction High-quality shared decision-making (SDM) is a priority of health services, but only achieved in a minority of surgical consultations. Improving SDM for surgical patients may lead to more effective care and moderate the impact of treatme
Externí odkaz:
https://doaj.org/article/f5c11afc5bf643bb9502e7a2f0583d0f
Autor:
Sarah M Frank, Lindsay M Jaacks, Christy L Avery, Linda S Adair, Katie Meyer, Donald Rose, Lindsey Smith Taillie
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296069 (2024)
BackgroundThe Planetary Health Diet Index (PHDI) measures adherence to the sustainable dietary guidance proposed by the EAT-Lancet Commission on Food, Planet, Health. To justify incorporating sustainable dietary guidance such as the PHDI in the US, t
Externí odkaz:
https://doaj.org/article/f8c623b823d34030a6a877d55c4a3a69
Autor:
Yilun Li, Kin Yau Wong, Annie Green Howard, Penny Gordon-Larsen, Heather M. Highland, Mariaelisa Graff, Kari E. North, Carolina G. Downie, Christy L. Avery, Bing Yu, Kristin L. Young, Victoria L. Buchanan, Robert Kaplan, Lifang Hou, Brian Thomas Joyce, Qibin Qi, Tamar Sofer, Jee-Young Moon, Dan-Yu Lin
Publikováno v:
HGG Advances, Vol 5, Iss 1, Pp 100245- (2024)
Summary: Mendelian randomization has been widely used to assess the causal effect of a heritable exposure variable on an outcome of interest, using genetic variants as instrumental variables. In practice, data on the exposure variable can be incomple
Externí odkaz:
https://doaj.org/article/cbe905cc5ce0437cbe3b05f57e464168