Zobrazeno 1 - 10
of 176
pro vyhledávání: '"L, Ashley Blackshaw"'
Autor:
Amisha A. Modasia, Emily J. Jones, L. Marie‐Pascale Martel, Hélène Louvel, Pierre‐Olivier Couraud, L. Ashley Blackshaw, Simon R. Carding
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 7, Pp n/a-n/a (2023)
Abstract Bacterial extracellular vesicles (BEVs) are increasingly seen as key signalling mediators between the gut microbiota and the host. Recent studies have provided evidence of BEVs ability to transmigrate across cellular barriers to elicit respo
Externí odkaz:
https://doaj.org/article/925203ac2f60439ba906416f391435e2
Autor:
Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-25 (2022)
Abstract Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we t
Externí odkaz:
https://doaj.org/article/cb0e43327b1d4f1c8b7dc50edb1d5e97
Autor:
Amisha Modasia, Aimee Parker, Emily Jones, Regis Stentz, Arlaine Brion, Andrew Goldson, Marianne Defernez, Tom Wileman, L. Ashley Blackshaw, Simon R. Carding
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Gut microbes have critical roles in maintaining host physiology, but their effects on epithelial chemosensory enteroendocrine cells (EEC) remain unclear. We investigated the role that the ubiquitous commensal gut bacterium Bacteriodes thetaiotaomicro
Externí odkaz:
https://doaj.org/article/2e650246e578484881084b10fba7d01a
Autor:
Eve Hornsby, Hamish W King, Madusha Peiris, Roberto Buccafusca, Wing-Yiu Jason Lee, Elinor S Wing, L Ashley Blackshaw, James O Lindsay, Andrew J Stagg
Publikováno v:
Journal of Leukocyte Biology. 112:365-381
Monocytes are mononuclear phagocytes that can differentiate to a variety of cell fates under the influence of their microenvironment and hardwired commitment. We found that inhibition of TRPM8 in human blood CD14+ monocytes during a critical 3-h wind
Autor:
Paulo da Silva Watanabe, Andreza Manzato Cavichioli, Joana D'Arc de Lima Mendes, Rubina Aktar, Madusha Peiris, L. Ashley Blackshaw, Eduardo José de Almeida Araújo
Publikováno v:
Life Sciences. 321:121642
Autor:
Aimée Parker, Stefano Romano, Rebecca Ansorge, Asmaa Aboelnour, Gwenaelle Le Gall, George M. Savva, Matthew G. Pontifex, Andrea Telatin, David Baker, Emily Jones, David Vauzour, Steven Rudder, L. Ashley Blackshaw, Glen Jeffery, Simon R. Carding
Publikováno v:
Microbiome. 10(1)
Background Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias. Here, we tested the
Autor:
Madusha Peiris, Rubina Aktar, Sarah Raynel, Zheng Hao, Michael B. Mumphrey, Hans-Rudolf Berthoud, L. Ashley Blackshaw
Publikováno v:
Nutrients, Vol 10, Iss 10, p 1529 (2018)
Background: Nutrient-sensing receptors located on enteroendocrine (EEC) cells modulate appetite via detection of luminal contents. Colonic ‘tasting’ of luminal contents may influence changes to appetite observed in obesity and after weight loss i
Externí odkaz:
https://doaj.org/article/076e4c75cb6f4c6f99cdfc0fb20125f8
Autor:
L. Ashley Blackshaw, Patrick A. Hughes, Andrea M. Harrington, Grigori Y. Rychkov, Stuart M. Brierley
Publikováno v:
Pharmaceuticals, Vol 3, Iss 9, Pp 2768-2798 (2010)
We are normally unaware of the complex signalling events which continuously occur within our internal organs. Most of us only become cognisant when sensations of hunger, fullness, urgency or gas arise. However, for patients with organic and functiona
Externí odkaz:
https://doaj.org/article/27d94b7bc1b244069cfcc2ef95c9b59f
Autor:
Rebecca Ansorge, Steven Rudder, Gwénaëlle Le Gall, L. Ashley Blackshaw, David Baker, Glen Jeffery, Emily Jones, Simon R. Carding, Stefano Romano, Andrea Telatin, Aimee Parker, Asmaa Aboelnoer, George M. Savva
Publikováno v:
SSRN Electronic Journal.
Altered intestinal microbiota composition in later life is associated with inflammaging and increased susceptibility to age–associated chronic diseases affecting various organs. Here we tested the hypothesis that manipulating the intestinal microbi
Autor:
Arlaine Brion, Amisha Modasia, Simon R. Carding, Emily J. Jones, Thomas Wileman, L. Ashley Blackshaw, Marianne Defernez, Andrew J. Goldson, Aimee Parker, Régis Stentz
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, Vol 11 (2020)
Gut microbes have critical roles in maintaining host physiology, but their effects on epithelial chemosensory enteroendocrine cells (EEC) remain unclear. We investigated the role that the ubiquitous commensal gut bacterium Bacteriodes thetaiotaomicro