Zobrazeno 1 - 10
of 177
pro vyhledávání: '"L, Aarden"'
Publikováno v:
British Journal of Pharmacology. 140:980-986
In addition to its central role in blood coagulation and hemostasis, human α-thrombin is a powerful regulator of inflammatory responses and is known to affect cell-mediated immunity. Interleukin (IL)-12 is a strong promoter of the development of Th1
Autor:
C. E. Van Der Schoot, M. de Haas, Claudia C. Folman, A. E. G. K. Von Dem Borne, L. Aarden, W. Gerritsen, I. H. J. A. M. Rensink
Publikováno v:
Thrombosis and Haemostasis. 78:1262-1267
SummaryIn this report a sensitive enzyme-linked immunosorbent assay (ELISA) for the measurement of plasma thrombopoietin (Tpo) is described that is solely based on monoclonal antibodies (MoAbs).The assay has an intra and inter-assay variance of 5-7%
Autor:
L. Aarden
Publikováno v:
Scandinavian Journal of Immunology. 62:33-35
In the mid-1970s, Ivan Lefkovits and co-workers introduced limiting dilution analysis of T and B cells as a method to quantify antigen-specific T and B cells. In this study, I describe how my co-operation with Ivan on the subject led not only to heat
Publikováno v:
British journal of pharmacology, 140(5), 980-986. Wiley-Blackwell
In addition to its central role in blood coagulation and hemostasis, human alpha-thrombin is a powerful regulator of inflammatory responses and is known to affect cell-mediated immunity. Interleukin (IL)-12 is a strong promoter of the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d5d56ea210dc0db40b59a648f4a47b2c
https://pure.amc.nl/en/publications/inhibition-of-interleukin12-expression-by-alphathrombin-in-human-peripheral-blood-mononuclear-cells-a-potential-mechanism-for-modulating-th1th2-responses(a280b3dd-1a6e-4bb7-86ec-3604aba1cf3b).html
https://pure.amc.nl/en/publications/inhibition-of-interleukin12-expression-by-alphathrombin-in-human-peripheral-blood-mononuclear-cells-a-potential-mechanism-for-modulating-th1th2-responses(a280b3dd-1a6e-4bb7-86ec-3604aba1cf3b).html
Publikováno v:
Annals of the Rheumatic Diseases. 73:A35.1-A35
Autor:
P. van Schouwenburg, L.A. van de Stadt, R. de Jong, E. van Buren, S. Kruithof, E. de Groot, M. Hart, M. van Ham, T. Rispens, L. Aarden, G. Wolbink, D. Wouters
Publikováno v:
Annals of the Rheumatic Diseases. 71:640.15-640
Publikováno v:
Blood. 87(12)
Acute inflammatory illnesses, including the sepsis syndrome, often include a component of coagulation. A human whole blood culture system was developed so that the relationship between coagulation activation and cytokine responses in the presence or
Publikováno v:
Leukemia. 7(10)
We studied the in vitro differentiation (immunoglobulin production) of purified malignant B cells of 21 patients with different B-cell malignancies, including chronic lymphocytic leukemia (CLL), prolymphocytic leukemia (PLL), hairy cell leukemia (HCL
Publikováno v:
European cytokine network. 4(5)
Five murine monoclonal antibodies, raised against E. coli derived human IL-4, were established. All mAb were also reactive with natural IL-4. Competition ELISA experiments revealed that mAb 1,2 and 4 recognized a related epitope on IL-4. mAb 5 and mA
Publikováno v:
Blood. 80(5)
The proliferative response of purified malignant B cells from 26 patients with chronic lymphocytic leukemia (CLL) was investigated in vitro. In the majority of these patients, a proliferative response could be induced by the combination of tumor necr