Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kyunglim, Kim"'
Autor:
Jakyung Yoo, Khai Phan, Inah Hwang, Zhan Guo Gao, Hunjoo Ha, Sun Choi, Akshata Nayak, Girish Chandra, Kyunglim Kim, Steven M. Moss, Minghua Cui, Pramod K. Sahu, Kuldeep K. Roy, Kenneth A. Jacobson, Lak Shin Jeong, Hea Ok Kim, Xiyan Hou, Yoonji Lee
Publikováno v:
Journal of Medicinal Chemistry
Truncated N(6)-substituted-(N)-methanocarba-adenosine derivatives with 2-hexynyl substitution were synthesized to examine parallels with corresponding 4'-thioadenosines. Hydrophobic N(6) and/or C2 substituents were tolerated in A3AR binding, but only
Autor:
Kenneth A. Jacobson, Lak Shin Jeong, Lena S. Yoo, Zhan Guo Gao, Jin Hee Lee, Hea Ok Kim, Xiyan Hou, Seul Gi Park, Sun Choi, Kyunglim Kim, Varughese Alexander
Publikováno v:
ACS Medicinal Chemistry Letters. 1:516-520
The truncated C2- and C8-substituted 4′-thioadenosine derivatives 4a−d were synthesized from d-mannose, using palladium-catalyzed cross-coupling reactions as key steps. In this study, an A3 adenosine receptor (AR) antagonist, truncated 4′-thioa
Publikováno v:
Journal of Food Science. 74:S135-S141
Green tea has been widely consumed for its mild flavors and its health benefits, yet caffeine in green tea has been a limitation for those who want to avoid it. The limitation brought increase in need for decaffeinated products in the green tea marke
Autor:
Kenneth A. Jacobson, Lak Shin Jeong, Won Jun Choi, Hwa Jin Chung, Hyuk Woo Lee, Varughese Alexander, Seul Gi Park, Jin Hee Lee, Yuna Pyee, Xiyan Hou, Khai Phan, Yoonji Lee, Hea Ok Kim, Sang Kook Lee, Girish Chandra, Kyunglim Kim, Mahesh S. Majik, Zhan Guo Gao, Sun Choi
Truncated N(6)-substituted-4'-oxo- and 4'-thioadenosine derivatives with C2 or C8 substitution were studied as dual acting A(2A) and A(3) adenosine receptor (AR) ligands. The lithiation-mediated stannyl transfer and palladium-catalyzed cross-coupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05baf81c09ad2dd18469cef53d70e4cf
https://europepmc.org/articles/PMC3266722/
https://europepmc.org/articles/PMC3266722/
Autor:
Xiyan, Hou, Hea Ok, Kim, Varughese, Alexander, Kyunglim, Kim, Sun, Choi, Seul-Gi, Park, Jin Hee, Lee, Lena S, Yoo, Zhan-Guo, Gao, Kenneth A, Jacobson, Lak Shin, Jeong
Publikováno v:
ACS medicinal chemistry letters. 2010(9)
The truncated C2- and C8-substituted-4'-thioadenosine derivatives 4a-d were synthesized from D-mannose, using palladium-catalyzed cross coupling reactions as key steps. In this study, an A(3) adenosine receptor (AR) antagonist, truncated 4'-thioadeno