Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kyungheon Lee"'
Autor:
Mikołaj Piotr Zaborowski, Kyungheon Lee, Young Jeong Na, Alessandro Sammarco, Xuan Zhang, Marcin Iwanicki, Pike See Cheah, Hsing-Ying Lin, Max Zinter, Chung-Yu Chou, Giulia Fulci, Bakhos A. Tannous, Charles Pin-Kuang Lai, Michael J. Birrer, Ralph Weissleder, Hakho Lee, Xandra O. Breakefield
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 255-268.e6 (2019)
Summary: Analysis of cancer-derived extracellular vesicles (EVs) in biofluids potentially provides a source of disease biomarkers. At present there is no procedure to systematically identify which antigens should be targeted to differentiate cancer-d
Externí odkaz:
https://doaj.org/article/f5811ae8179b4dfaa6de8cd19a6060d7
Autor:
Hyun Jung Chung, Kathryn L Pellegrini, Jaehoon Chung, Kamani Wanigasuriya, Innocent Jayawardene, Kyungheon Lee, Hakho Lee, Vishal S Vaidya, Ralph Weissleder
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133417 (2015)
The high incidence of acute and chronic kidney injury due to various environmental factors such as heavy metals or chemicals has been a major problem in developing countries. However, the diagnosis of kidney injury in these areas can be more challeng
Externí odkaz:
https://doaj.org/article/18b5907694d34a7caa3e1327b37d7cfe
Autor:
Firdausi Qadri, Richelle C. Charles, Ralph Weissleder, Soo Jin Kim, Sohyeon Park, Hakho Lee, Jun S. Song, Farhana Khanam, Changwook Min, Taufiqur Rahman Bhuiyan, Kyungheon Lee, H. Y. Kim, Ki Soo Park, Rasheduzzaman Rashu, Edward T. Ryan, Jinwoo Cheon
Publikováno v:
ACS Nano
Pathogen activated antibody-secreting cells (ASCs) produce and secrete antigen-specific antibodies. ASCs are detectable in the peripheral blood as early as 3 days after antigen exposure, which makes ASCs a potential biomarker for early disease detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5854e2b4abc16db5fd61dabc9042035
https://doi.org/10.1021/acsnano.7b06074
https://doi.org/10.1021/acsnano.7b06074
Autor:
Ahmed T. Kurdi, Ralph Weissleder, Leonardo V. Riella, Jamil Azzi, Sangmoo Jeong, Hsing Ying Lin, Siawosh K. Eskandari, Sujit Routray, Anil Chandraker, Kyungheon Lee, Kyle B. Fraser, Bakhos A. Tannous, Jean Pierre Assaker, Chen Han Huang, Changwook Min, Hakho Lee, Jongmin Park, Cesar M. Castro, Reza Abdi
Publikováno v:
ACS Nano. 11:11041-11046
Kidney transplant patients require life-long surveillance to detect allograft rejection. Repeated biopsy, albeit the clinical gold standard, is an invasive procedure with the risk of complications and comparatively high cost. Conversely, serum creati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf395aaa122b916c87a4e5eb373dd67
https://doi.org/10.1021/acsnano.7b05083
https://doi.org/10.1021/acsnano.7b05083
Publikováno v:
Lab on a Chip. 17:2892-2898
Exosomes have recently emerged as highly promising cancer biomarkers because they are abundant in biofluids, carry proteins and RNA reflecting their originating cells and are stable over weeks. Beyond abundance and stability, detailed exosome analyse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bc0910421f7479c8e9d2ef0c23d8f3
https://doi.org/10.1039/c7lc00247e
https://doi.org/10.1039/c7lc00247e
Autor:
Hakho Lee, Ralph Weissleder, Pike See Cheah, Charles P. Lai, Markus W. Schweiger, Bakhos A. Tannous, Alessandro Sammarco, Bence György, Kyungheon Lee, Massimo Aufiero, Kasey C. Vickers, Xandra O. Breakefield, Isabella Bushko, Sybren L. N. Maas, Purva H. Rumde, Xuan Zhang, Ryan M. Allen, Valentina Zappulli, Mikołaj Piotr Zaborowski
Publikováno v:
Scientific Reports, 9(1). Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Extracellular vesicles (EVs) released by cells play a role in intercellular communication. Reporter and targeting proteins can be modified and exposed on the surface of EVs to investigate their half-life and biodistribution. A characterization of mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908bd6b3f80eefcd48304f4334ff660e
http://hdl.handle.net/11577/3322512
http://hdl.handle.net/11577/3322512
Autor:
Max Zinter, Ralph Weissleder, Michael J. Birrer, Charles P. Lai, Marcin P. Iwanicki, Chung-Yu Chou, Xuan Zhang, Giulia Fulci, Hsing Ying Lin, Bakhos A. Tannous, Young Jeong Na, Xandra O. Breakefield, Alessandro Sammarco, Mikołaj Piotr Zaborowski, Kyungheon Lee, Hakho Lee, Pike See Cheah
Publikováno v:
Cell reports
Cell Reports, Vol 27, Iss 1, Pp 255-268.e6 (2019)
Cell Reports, Vol 27, Iss 1, Pp 255-268.e6 (2019)
SUMMARY Analysis of cancer-derived extracellular vesicles (EVs) in biofluids potentially provides a source of disease biomarkers. At present there is no procedure to systematically identify which antigens should be targeted to differentiate cancer-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11515a65c9eaf65bea1e787c76825e8e
https://pubmed.ncbi.nlm.nih.gov/30943406
https://pubmed.ncbi.nlm.nih.gov/30943406
Autor:
Jeffrey M. Treiber, Ichiro Nakano, Manfred Westphal, Quazim A. Alayo, Tyler Steed, Leonora Balaj, Hiroshi Nakashima, Franz Ricklefs, Jakub Godlewski, Hakho Lee, Harald Krenzlin, Gordon J. Freeman, Arun K. Rooj, Kyungheon Lee, Ahmad Bakur Mahmoud, Carmela Passaro, Katrin Lamszus, Ralph Weissleder, Clark C. Chen, Bob S. Carter, Scott J. Rodig, Agnieszka Bronisz, Susanne Krasemann, Sean E. Lawler, Josie Hayes, Katherine Yang, E. Antonio Chiocca, Maria C. Speranza, Xandra O. Breakefield
Publikováno v:
Science Advances
Glioblastoma can suppress immunity by using surface PD-L1 on extracellular vesicles to block T cell receptor–mediated T cell activation.
Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1) leads to cancer immu
Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1) leads to cancer immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d2659579f32e16357b212b44a70788
https://doi.org/10.1126/sciadv.aar2766
https://doi.org/10.1126/sciadv.aar2766
Autor:
Hakho Lee, Xandra O. Breakefield, Ralph Weissleder, Leonora Balaj, Kyungheon Lee, Kyle B. Fraser, Bassel Ghaddar, Eunha Kim, E. Antonio Chiocca, Katy Yang
Extracellular vesicles (EV) are a family of cell-originating, membrane-enveloped nanoparticles with diverse biological function, diagnostic potential, and therapeutic applications. While EV can be abundant in circulation, their small size (∼4 order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caefd1ae306b01ad099cd3f00396038
https://europepmc.org/articles/PMC5898240/
https://europepmc.org/articles/PMC5898240/
Publikováno v:
ACS Nano. 9:2321-2327
Microvesicles (MVs) are an increasingly important source for biomarker discovery and clinical diagnostics. The small size of MVs and their presence in complex biological environment, however, pose technical challenges in sample preparation, particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6c699bad78dee523137f30df1331cc
https://doi.org/10.1021/nn506538f
https://doi.org/10.1021/nn506538f