Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Kyung-Ok Cho"'
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Magnetic resonance fingerprinting (MRF) enables fast myelin quantification via the myelin water fraction (MWF), offering a noninvasive method to assess brain development and disease. However, MRF-derived MWF lacks histological eva
Externí odkaz:
https://doaj.org/article/3a18f2b9be694f58b8603fe82601625e
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Multiple genome sequencing studies have identified genetic abnormalities as major causes of severe intellectual disability (ID). However, many children affected by mild ID and borderline intellectual functioning (BIF) lack a genetic diagnosis because
Externí odkaz:
https://doaj.org/article/69c6006916a546dbbb5c9c891618e215
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Temporal lobe epilepsy (TLE) is one of the most common neurological disorders, but still one-third of patients cannot be properly treated by current medication. Thus, we investigated the therapeutic effects of a novel small molecule, NecroX-7, in TLE
Externí odkaz:
https://doaj.org/article/fe1ce44c95ec4268a1ab824b7bd063c2
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/c6feb48a4b1949e49129132dfa1325df
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Anxiety disorder is one of the most common comorbidities in temporal lobe epilepsy (TLE), but its neurobiological mechanisms remain unclear. Here we identified a novel target, interleukin-17A (IL-17A), which can contribute to TLE-associated anxiety.
Externí odkaz:
https://doaj.org/article/63a2c5e5fd524a2fa870cc8848cde4a0
Autor:
Zane R. Lybrand, Sonal Goswami, Jingfei Zhu, Veronica Jarzabek, Nikolas Merlock, Mahafuza Aktar, Courtney Smith, Ling Zhang, Parul Varma, Kyung-Ok Cho, Shaoyu Ge, Jenny Hsieh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Adult-born granule cells integrate in hippocampal circuitry and contribute to hippocampal function. Here, the authors show that a critical period of neuronal activity regulates aberrant neurogenesis to rewire hippocampal circuitry and drive seizures
Externí odkaz:
https://doaj.org/article/cd230e45dae0415ca0fb2fb0eaf34de2
Autor:
Sang-Soo Lee, Jong-Hoon Won, Gippeum J. Lim, Jeongran Han, Ji Youn Lee, Kyung-Ok Cho, Young-Kyung Bae
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Extracellular vesicles (EVs) play important roles in intercellular communication by delivering RNA, lipid, and proteins to neighboring or distant cells. Identification and classification of EVs secreted from diverse cell types are
Externí odkaz:
https://doaj.org/article/4f1e803868df48a1b5d111be04214a53
Autor:
Ja Un Moon, Kyung-Ok Cho
Publikováno v:
International Neurourology Journal, Vol 25, Iss Suppl 1, Pp S8-18 (2021)
Epileptic encephalopathy (EE) is a devastating pediatric disease that features medically resistant seizures, which can contribute to global developmental delays. Despite technological advancements in genetics, the neurobiological mechanisms of EEs ar
Externí odkaz:
https://doaj.org/article/1d10bc5d89fb4495b83cec86d57e4d99
Publikováno v:
International Neurourology Journal, Vol 22, Iss 1, Pp 2-8 (2018)
Micturition is a complex process involving the bladder, spinal cord, and the brain. Highly sophisticated central neural program controls bladder function by utilizing multiple brain regions, including pons and suprapontine structures. Periaqueductal
Externí odkaz:
https://doaj.org/article/c27c759da02745ac95ddf8ebc5cc3f1d
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 43 (2021)
Dynein is a multi-subunit motor protein that moves toward the minus-end of microtubules, and plays important roles in fly development. We identified Dhc64Cm115, a new mutant allele of the fly Dynein heavy chain 64C (Dhc64C) gene whose heterozygotes s
Externí odkaz:
https://doaj.org/article/4742c689bff04e18a1d92efe03e6100a