Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Kyung-Min Yang"'
Autor:
Min Kyoung Jo, Chang Mo Moon, Hyeon-Jeong Jeon, Yerim Han, Eun Sook Lee, Ji-Hee Kwon, Kyung-Min Yang, Young-Ho Ahn, Seong-Eun Kim, Sung-Ae Jung, Tae Il Kim
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-15 (2023)
Abstract Background This study aimed to investigate how aging alters the homeostasis of the colonic intestinal epithelium and regeneration after tissue injury using organoid models and to identify its underlying molecular mechanism. Methods To invest
Externí odkaz:
https://doaj.org/article/567146b7d6bb438789e49814da7e8e9c
Autor:
Jaewon Lee, Jihoon Ha, Jun-Hyeong Kim, Dongyeob Seo, Minbeom Kim, Yerin Lee, Seong Shil Park, Dahee Choi, Jin Seok Park, Young Jae Lee, Siyoung Yang, Kyung-Min Yang, Su Myung Jung, Suntaek Hong, Seung-Hoi Koo, Yong-Soo Bae, Seong-Jin Kim, Seok Hee Park
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1218-1231 (2023)
Abstract The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induced liver injury. Here, we examine
Externí odkaz:
https://doaj.org/article/1c46d3af0ff845178e5fd7a36536788b
Autor:
Jihee Lee, Kyoungwha Pang, Junil Kim, Eunji Hong, Jeeyun Lee, Hee Jin Cho, Jinah Park, Minjung Son, Sihyun Park, Minjung Lee, Akira Ooshima, Kyung-Soon Park, Han-Kwang Yang, Kyung-Min Yang, Seong-Jin Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
ESRP1 is reported to regulate the alternative splicing of some genes involved in epithelial–mesenchymal transition. Here the authors show that LRRFIP2 is a target of ESRP1 and that two spliced variants of LRRFIP2 have opposing functions in gastric
Externí odkaz:
https://doaj.org/article/afa434b360b645c28b2b450729e42293
Autor:
Pyunggang Kim, Jinah Park, Dong-Joon Lee, Seiya Mizuno, Masahiro Shinohara, Chang Pyo Hong, Yealeen Jeong, Rebecca Yun, Hyeyeon Park, Sujin Park, Kyung-Min Yang, Min-Jung Lee, Seung Pil Jang, Hyun-Yi Kim, Seung-Jun Lee, Sun U. Song, Kyung-Soon Park, Mikako Tanaka, Hayato Ohshima, Jin Won Cho, Fumihiro Sugiyama, Satoru Takahashi, Han-Sung Jung, Seong-Jin Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Controlling fate decision of mesenchymal stromal cells (MSC) is important for their clinical application. Here the authors demonstrate that TGF-β-induced Mast4 suppression and Wnt-mediated Mast4 stabilization regulate MSC differentiation into cartil
Externí odkaz:
https://doaj.org/article/772a40cc1ab9487eb361fa1e59c50fe2
Autor:
Kyoungwha Pang, Jihee Lee, Junil Kim, Jinah Park, Yuna Park, Eunji Hong, Haein An, Akira Ooshima, Minjung Son, Kyung-Soon Park, Jae-Hyun Cho, Cheol Lee, Yong Sang Song, Kyung-Min Yang, Seong-Jin Kim
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-11 (2022)
Abstract Despite favorable responses to initial chemotherapy, drug resistance is a major cause limiting chemotherapeutic efficacy in many advanced cancers. However, mechanisms that drive drug-specific resistance in chemotherapy for patients with adva
Externí odkaz:
https://doaj.org/article/d84fc8751eab471087f03f043228b367
Autor:
Haein An, Jin Sun Heo, Pyunggang Kim, Zenglin Lian, Siyoung Lee, Jinah Park, Eunji Hong, Kyoungwha Pang, Yuna Park, Akira Ooshima, Jihee Lee, Minjung Son, Hyeyeon Park, Zhaoyan Wu, Kyung-Soon Park, Seong-Jin Kim, Illju Bae, Kyung-Min Yang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract Although tetraarsenic hexoxide is known to exert an anti-tumor effect by inducing apoptosis in various cancer cells, its effect on other forms of regulated cell death remains unclear. Here, we show that tetraarsenic hexoxide induces the pyro
Externí odkaz:
https://doaj.org/article/574bb1d037cc47d68d279ac20092e4ae
Autor:
Kazuhito Naka, Ryosuke Ochiai, Eriko Matsubara, Chie Kondo, Kyung-Min Yang, Takayuki Hoshii, Masatake Araki, Kimi Araki, Yusuke Sotomaru, Ko Sasaki, Kinuko Mitani, Dong-Wook Kim, Akira Ooshima, Seong-Jin Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
How lipid metabolism can affect cancer recurrence is still unclear. Here, the authors show that the lysophospholipase D Gdpd3 maintains self-renewal capacity of CML stem cells by regulating the quiescence, and AKT/mTORC1 and Foxo3a/β-catenin signall
Externí odkaz:
https://doaj.org/article/73aca2b556d542e499ca1a950b353d8d
Autor:
Kyoungwha Pang, Jinah Park, Sung Gwe Ahn, Jihee Lee, Yuna Park, Akira Ooshima, Seiya Mizuno, Satoshi Yamashita, Kyung-Soon Park, So-Young Lee, Joon Jeong, Toshikazu Ushijima, Kyung-Min Yang, Seong-Jin Kim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Triple-negative breast cancer (TNBC) is an aggressive subtype lacking effective targeted therapies. Here, the authors show that RNF208, an estrogen-induced ubiquitin ligase, promotes the degradation of Vimentin, thereby suppressing lung metastasis of
Externí odkaz:
https://doaj.org/article/9f80aa90665541f5b148e27077feb9a0
Autor:
Kum-Hee Yun, Changhee Park, Hyang Joo Ryu, Chan-Young Ock, Young Han Lee, Wooyeol Baek, Hong In Yoon, Yoon Dae Han, Sang Kyum Kim, JooHee Lee, Seong-Jin Kim, Kyung-Min Yang, Seung Hyun Kim, Hyo Song Kim
Publikováno v:
Cancers, Vol 14, Iss 23, p 5975 (2022)
(1) Background: Desmoid tumors have a relatively high local failure rate after primary treatment using surgery and/or radiotherapy. Moreover, desmoid tumors recur at the primary site for many patients. An effective therapeutic strategy for the desmoi
Externí odkaz:
https://doaj.org/article/b040cc64ad7e4d8fb156fb9a3a5f6c7e
Autor:
Kyung-Min Yang, Eunjin Bae, Sung Gwe Ahn, Kyoungwha Pang, Yuna Park, Jinah Park, Jihee Lee, Akira Ooshima, Bora Park, Junil Kim, Yunshin Jung, Satoru Takahashi, Joon Jeong, Seok Hee Park, Seong-Jin Kim
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2952-2964 (2017)
Summary: Triple-negative breast cancer (TNBC) is considered incurable with currently available treatments, highlighting the need for therapeutic targets and predictive biomarkers. Here, we report a unique role for Bcl-2-associated athanogene 2 (BAG2)
Externí odkaz:
https://doaj.org/article/dca5788d6a30436b8fb6fdb4ccc26f2a