Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Kyung-Hyun Yoo"'
Autor:
Dae‐Hwan Kim, Minjeong Sung, Myong‐Suk Park, Eun‐Gene Sun, Sumin Yoon, Kyung Hyun Yoo, Kamalakannan Radhakrishnan, Sung Yun Jung, Woo‐Kyun Bae, Sang‐Hee Cho, Ik‐Joo Chung
Publikováno v:
Cancer Communications, Vol 44, Iss 10, Pp 1106-1129 (2024)
Abstract Background Increased Galectin 3‐binding protein (LGALS3BP) serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma (HCC). Considering the crucial role of transforming growth factor‐β1 (
Externí odkaz:
https://doaj.org/article/c3b44f6f6e2b460c8e2108f0bb0c616e
Autor:
Sumin Oh, Yang-Hyun Baek, Sungju Jung, Sumin Yoon, Byeonggeun Kang, Su-hyang Han, Gaeul Park, Je Yeong Ko, Sang-Young Han, Jin-Sook Jeong, Jin-Han Cho, Young-Hoon Roh, Sung-Wook Lee, Gi-Bok Choi, Yong Sun Lee, Won Kim, Rho Hyun Seong, Jong Hoon Park, Yeon-Su Lee, Kyung Hyun Yoo
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 2, Pp 247-262 (2024)
Background/Aims Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by fat accumulation in the liver. MASLD encompasses both steatosis and MASH. Since MASH can lead to cirrhosis and liver cancer, steatosis and MASH must
Externí odkaz:
https://doaj.org/article/48cc13211e374b62bfd0cb799c9574e8
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 2, Pp 287-290 (2024)
Externí odkaz:
https://doaj.org/article/7caef509934a4539bc53d6baca253b26
Autor:
Eun-Gene Sun, Veena Vijayan, Mi-Ra Park, Kyung Hyun Yoo, Sang-Hee Cho, Woo-Kyun Bae, Hyun-Jeong Shim, Jun-Eul Hwang, In-Kyu Park, Ik-Joo Chung
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Transforming growth factor-β-activated kinase 1 (TAK1), which is highly expressed and aberrantly activated in triple-negative breast cancer (TNBC), plays a pivotal role in metastasis and progression. This makes it a potential therapeutic ta
Externí odkaz:
https://doaj.org/article/c6043b8139e5430ba5ffbcaeb1099a5e
Autor:
Sung‐Min Park, Jung‐Hwan Lee, Kwang Sung Ahn, Hye Won Shim, Ji‐Young Yoon, Jeongeun Hyun, Jun Hee Lee, Sunyoung Jang, Kyung Hyun Yoo, Yoon‐Kwan Jang, Tae‐Jin Kim, Hyun Kyu Kim, Man Ryul Lee, Jun‐Hyeog Jang, Hosup Shim, Hae‐Won Kim
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Advancing the technologies for cellular reprogramming with high efficiency has significant impact on regenerative therapy, disease modeling, and drug discovery. Biophysical cues can tune the cell fate, yet the precise role of external physic
Externí odkaz:
https://doaj.org/article/e33d70cb762d44bd8b98683ebb4a70ba
Autor:
Bobae Yang, Sueun Kim, Woong-Jae Jung, Kyungwoo Kim, Sugyung Kim, Yong-Jin Kim, Tae-Gyun Kim, Eun-Chong Lee, Jung-Sik Joo, Chae Gyu Park, Sumin Oh, Kyung Hyun Yoo, Hyoung-Pyo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The role of 3D genome organization is not well understood in the transcriptional regulation of dendritic cells. Here the authors show that activation of dendritic cells in vitro induces dynamic reprogramming of the chromatin looping and enhancer acti
Externí odkaz:
https://doaj.org/article/1d7c28e1932d4ffe981e0460b6615476
Autor:
Jin Gu Cho, Sung-wook Kim, Aram Lee, Ha-neul Jeong, Eunsik Yun, Jihea Choi, Su Jin Jeong, Woochul Chang, Sumin Oh, Kyung Hyun Yoo, Jung Bok Lee, Sukjoon Yoon, Myeong-Sok Lee, Jong Hoon Park, Min Hyung Jung, So-Woon Kim, Ki Hyung Kim, Dong Soo Suh, Kyung Un Choi, Jungmin Choi, Jongmin Kim, Byung Su Kwon
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 803-822 (2022)
Cancer stem-like cells (CSCs) have been suggested to be responsible for chemoresistance and tumor recurrence owing to their self-renewal capacity and differentiation potential. Although WEE1 is a strong candidate target for anticancer therapies, its
Externí odkaz:
https://doaj.org/article/2292e1739f1e48f0a24e453d19fda611
Publikováno v:
Journal of the Korean Society of Manufacturing Technology Engineers. 32:101-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::803643ed727c72b4f11d863bd079537f
https://doi.org/10.7735/ksmte.2023.32.2.101
https://doi.org/10.7735/ksmte.2023.32.2.101
Autor:
Eun Ji Lee, Je Yeong Ko, Sumin Oh, Jaehee Jun, Hyowon Mun, Chae Ji Lim, Seungwoon Seo, Hyuk Wan Ko, Hyunho Kim, Yun Kyu Oh, Curie Ahn, Minyong Kang, Min Jung Kim, Kyung Hyun Yoo, Goo Taeg Oh, Jong Hoon Park
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102986- (2020)
Background: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic target in PKD, and mammalian target of rapamycin (mTOR) is a key negative regu
Externí odkaz:
https://doaj.org/article/e47521daf26b4f3fa0fb63d2245de788
Autor:
Ha Youn Shin, Chaochen Wang, Hye Kyung Lee, Kyung Hyun Yoo, Xianke Zeng, Tyler Kuhns, Chul Min Yang, Teresa Mohr, Chengyu Liu, Lothar Hennighausen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
CRISPR/Cas9 gene editing has been used to generate mutations in several mouse genes. Here, the authors show that targeting events using single guide RNAs cause large deletions at 17 sites in the mouse genome, suggesting that careful genotyping is nee
Externí odkaz:
https://doaj.org/article/4fbfd858eb664ea8891c7763c979d634