Zobrazeno 1 - 10
of 592
pro vyhledávání: '"Kyung-Hun Lee"'
Autor:
Emi Noguchi, Takashi Yamanaka, Hirofumi Mukai, Naohito Yamamoto, Chi-Feng Chung, Yen-Shen Lu, Dwan-Ying Chang, Joohyuk Sohn, Gun Min Kim, Kyung-Hun Lee, Soo-Chin Lee, Tsutomu Iwasa, Hiroji Iwata, Kenichi Watanabe, Kyung Hae Jung, Yuko Tanabe, Seok Yun Kang, Hiroyuki Yasojima, Kenjiro Aogi, Eriko Tokunaga, Sung Hoon Sim, Yoon Sim Yap, Koji Matsumoto, Ling-Ming Tseng, Yoshiko Umeyama, Kazuki Sudo, Yuki Kojima, Tomomi Hata, Aya Kuchiba, Taro Shibata, Kenichi Nakamura, Yasuhiro Fujiwara, Kenji Tamura, Kan Yonemori
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Palbociclib combined with endocrine therapy is approved for treating patients with hormone-receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2−) advanced breast cancer; however, data on palbociclib combined with t
Externí odkaz:
https://doaj.org/article/3cba658e7441401e9b9e50ad16a29171
Autor:
Yongjoo Kim, Chan-Woo Yeom, Hyun Jeong Lee, Jeong-Hyun Kim, Kwang-Min Lee, Tae-Yong Kim, Han-Byoel Lee, Hoon Kim, Seock-Ah Im, Kyung-Hun Lee, Miso Kim, Wonsik Han, Hyeong-Gon Moon, David Spiegel, Bong-Jin Hahm, Kyung-Lak Son
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Hot flashes (HF) are a common adverse event of prolonged tamoxifen use in women with estrogen receptor-positive breast cancer, impacting psychiatric health and quality of life. While desvenlafaxine does not interact with tamoxifen, its effic
Externí odkaz:
https://doaj.org/article/01f6553895bd47baae9c2e4166efdbe0
Autor:
Jeayeon Park, Yun Bin Lee, Yunmi Ko, Youngsu Park, Hyunjae Shin, Moon Haeng Hur, Min Kyung Park, Dae-Won Lee, Eun Ju Cho, Kyung-Hun Lee, Jeong-Hoon Lee, Su Jong Yu, Tae-Yong Kim, Yoon Jun Kim, Tae-You Kim, Jung-Hwan Yoon
Publikováno v:
Journal of Liver Cancer, Vol 24, Iss 1, Pp 81-91 (2024)
Background/Aim Atezolizumab plus bevacizumab and lenvatinib are currently available as first-line therapy for the treatment of unresectable hepatocellular carcinoma (HCC). However, comparative efficacy studies are still limited. This study aimed to i
Externí odkaz:
https://doaj.org/article/0fba6f18253441e3be10280165c026e9
Autor:
Jong-Ho Cheun, Youngji Kwak, Eunhye Kang, Ji-Jung Jung, Hong-Kyu Kim, Han-Byoel Lee, Kyung-Hun Lee, Hyeong-Gon Moon, Ki-Tae Hwang, Yeon Hee Park, Jeong Eon Lee, Wonshik Han
Publikováno v:
Breast, Vol 78, Iss , Pp 103828- (2024)
Background: Neoadjuvant chemotherapy (NACT) for early-stage breast cancer is associated with an increased risk of locoregional recurrence (LRR). We investigated whether the risk of LRR after NACT varies across tumor subtypes. Methods: We retrospectiv
Externí odkaz:
https://doaj.org/article/69e72bca1dc84536b9d19caab0c3937b
Autor:
Seungju Yang, San Hae Im, Ju Yeon Chung, Juhee Lee, Kyung‐Hun Lee, Yoo Kyung Kang, Hyun Jung Chung
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract The CRISPR/Cas system has been introduced as an innovative tool for therapy, however achieving specific delivery to the target has been a major challenge. Here, an antibody‐CRISPR/Cas conjugate platform that enables specific delivery and t
Externí odkaz:
https://doaj.org/article/e491e54803a94d9ab7ae1524d1bc8e43
Autor:
Jeongmin Seo, Jiwon Koh, Dae-Won Lee, Jinyong Kim, Han Suk Ryu, Kyung-Hun Lee, Tae-Yong Kim, Seock-Ah Im
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background The role of HER2 amplification level in predicting the effectiveness of HER2-directed therapies has been established. However, its association with survival outcomes in advanced HER2-positive breast cancer treated with dual HER2-b
Externí odkaz:
https://doaj.org/article/3baff563765d491e86fc3d30af39cc2a
Autor:
Armando Santoro, Eric Assenat, Thomas Yau, Jean-Pierre Delord, Michela Maur, Jennifer Knox, Stephane Cattan, Kyung-Hun Lee, Gianluca Del Conte, Christoph Springfeld, Elisa Leo, Alexandros Xyrafas, Lauren Fairchild, Feby Mardjuadi, Stephen L. Chan
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101021- (2024)
Background & aims: This phase Ib/II trial evaluated the safety and efficacy of capmatinib in combination with spartalizumab or spartalizumab alone in patients with advanced hepatocellular carcinoma (HCC). Methods: Eligible patients who had progressed
Externí odkaz:
https://doaj.org/article/9e42ee62344d4ac28b99c8e6f48601dc
Autor:
Yeon Hee Park, Seock-Ah Im, Kyunghee Park, Ji Wen, Kyung-Hun Lee, Yoon-La Choi, Won-Chul Lee, Ahrum Min, Vinicius Bonato, Seri Park, Sripad Ram, Dae-Won Lee, Ji-Yeon Kim, Su Kyeong Lee, Won-Woo Lee, Jisook Lee, Miso Kim, Hyun Seon Kim, Scott L. Weinrich, Han Suk Ryu, Tae Yong Kim, Stephen Dann, Yu-Jin Kim, Diane R. Fernandez, Jiwon Koh, Shuoguo Wang, Song Yi Park, Shibing Deng, Eric Powell, Rupesh Kanchi Ravi, Jadwiga Bienkowska, Paul A. Rejto, Woong-Yang Park, Zhengyan Kan
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Cyclin-dependent kinase 4/6 inhibitor (CDK4/6) therapy plus endocrine therapy (ET) is an effective treatment for patients with hormone receptor-positive/human epidermal receptor 2-negative metastatic breast cancer (HR+/HER2− MBC
Externí odkaz:
https://doaj.org/article/e43bea5e36154033b3975c0ba6d40d38
Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia
Autor:
Changhu Lee, Min Kim, Chanho Park, Woobeen Jo, Jeong Kon Seo, Sahee Kim, Jiyoung Oh, Chu-Sook Kim, Han Suk Ryu, Kyung-Hun Lee, Jiyoung Park
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Despite hyperglycemia has been associated to breast cancer, the underlying mechanisms are not completely understood. Here, the authors show that epigenetic regulation of Nrg1 gene during hyperglycemia promotes breast cancer development.
Externí odkaz:
https://doaj.org/article/70307856217b44f6a9332ad61e67b385
Autor:
Jinyong Kim, Kyeonghun Jeong, Hyeji Jun, Kwangsoo Kim, Jeong Mo Bae, Myung Geun Song, Hanbaek Yi, Songyi Park, Go-un Woo, Dae-Won Lee, Tae-Yong Kim, Kyung-Hun Lee, Seock-Ah Im
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)
Abstract Background Germline mutations of breast cancer susceptibility gene BRCA1 and BRCA2 (gBRCA1/2) are associated with elevated risk of breast cancer in young women in Asia. BRCA1 and BRCA2 proteins contribute to genomic stability through homolog
Externí odkaz:
https://doaj.org/article/97b9dd8354224e9d95a8194d50a2dc88