Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kyung-Ah Seo"'
Autor:
Yazun Bashir Jarrar, Eun-Young Cha, Kyung-Ah Seo, Jong-Lyul Ghim, Hyo-Ji Kim, Dong-Hyun Kim, Su-Jun Lee, Jae-Gook Shin
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2334-2342 (2014)
The compound 20-HETE is involved in numerous physiological functions, including blood pressure and platelet aggregation. Glucuronidation of 20-HETE by UDP-glucuronosyltransferases (UGTs) is thought to be a primary pathway of 20-HETE elimination in hu
Externí odkaz:
https://doaj.org/article/d955e0afd3da41f9b66a74583ab6d373
Publikováno v:
Korean Journal of Pediatrics, Vol 56, Iss 10, Pp 446-450 (2013)
PurposeThis study evaluated the extent of damage due to hypothermia in the mature and immature brain.MethodsHippocampal tissue cultures at 7 and 14 days in vitro (DIV) were used to represent the immature and mature brain, respectively. The cultures w
Externí odkaz:
https://doaj.org/article/e939b554e9c5474bbb9fbeb23133eaa3
Autor:
Younho, Lee, Hyunkyung, Kim, Haelee, Kim, Ha Yeon, Cho, Jun-Goo, Jee, Kyung-Ah, Seo, Jung Beom, Son, Eunhwa, Ko, Hwan Geun, Choi, Nam Doo, Kim, Ikyon, Kim
Publikováno v:
Journal of medicinal chemistry. 64(10)
Triple-negative breast cancer (TNBC) is an aggressive breast-cancer subtype associated with poor prognosis and high relapse rates. Monopolar spindle 1 kinase (MPS1) is an apical dual-specificity protein kinase that is over-expressed in TNBC. We herei
Publikováno v:
Journal of Chromatography B. 1072:86-93
Metabolomics combined with high-resolution mass spectrometry (HR-MS) and multivariate data analysis has broad applications in the study of xenobiotic metabolism. Although information about xenobiotic metabolism is essential to understand toxic mechan
Autor:
Jong Ryul Ghim, Hyun Kyung Lee, Kyung Ah Seo, Seung Heon Lee, Chol Shin, Youngmin Lee, Jae-Gook Shin, Dong-Hyun Kim, Je Hyeong Kim
Publikováno v:
Yonsei Medical Journal
Purpose: Low serum concentrations of drugs used to treat multi-drug resistant tuberculosis (MDR-TB) have occasionally been associated with treatment failure. We determined the frequencies of low serum concentrations of anti-MDR-TB drugs, and assessed
Publikováno v:
Neonatal Medicine. Nov2013, Vol. 20 Issue 4, p462-469. 8p.
Autor:
Nagi Abdalla, Jae-Gook Shin, Dong-Hyun Kim, Eun Sook Jeong, Hyo-Ji Kim, Kyung-Ah Seo, Chang-Soo Choi
Publikováno v:
Drug Metabolism and Disposition. 42:1803-1810
UDP-glucuronosyltransferase (UGT)-mediated drug-drug interactions are commonly evaluated during drug development. We present a validated method for the simultaneous evaluation of drug-mediated inhibition of six major UGT isoforms, developed in human
Autor:
Kang Sein, Jaeyoung Ahn, Hyun Kyung Kim, Kang Juhee, Younho Lee, Son Jung Beom, Kyung-ah Seo, Ji Eun Choi, Nam Doo Kim
Publikováno v:
Cancer Research. 79:2211-2211
There are many cell cycle regulating kinases such as CDKs, Polo, Aurora, Bub, NEK/NimA, etc. Dual specificity protein kinase, MPS1(TTK) is one of them. The role of MPS1 is to regulate spindle assembly checkpoint(SAC) during cell mitosis. The inhibiti
Autor:
Hyun Kyung Kim, Kim Hwan, Nam Doo Kim, Jo Seohyun, Ji Eun Choi, Ji-hoon Oh, Do Woomi, Son Jung Beom, Kyung-ah Seo, Li Hua, Jaeyoung Ahn
Publikováno v:
Cancer Research. 79:2209-2209
The rearranged during transfection (RET) tyrosine kinase is mostly altered by fusion and it makes RET as a attractive therapeutic target for medullary thyroid cancer and non-small cell lung cancer (NSCLC). Multi-kinase inhibitors (mKIs) such as caboz
Autor:
Kyung Ah Seo1, Na Mi Lee1 piena81@hotmail.com, Gwang Jun Kim2, Sin Weon Yun1, Soo Ahn Chae1, In Seok Lim1, Eung Sang Choi1, Byoung Hoon Yoo1
Publikováno v:
Pediatric Gastroenterology, Hepatology & Nutrition. Sep2013, Vol. 16 Issue 3, p195-199. 5p.