Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kyung U. Hong"'
Publikováno v:
FEBS Open Bio, Vol 14, Iss 9, Pp 1526-1539 (2024)
Cytoskeleton‐associated protein 2‐like (CKAP2L) is a paralogue of cytoskeleton‐associated protein 2 (CKAP2). We characterized the expression pattern, subcellular localization, and microtubule‐stabilizing properties of human CKAP2L. The levels
Externí odkaz:
https://doaj.org/article/dc4f0e31444b4c8481821dddb0b7eeee
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Arylamine N-acetyltransferase 2 (NAT2) is a phase II metabolic enzyme, best known for metabolism of aromatic amines and hydrazines. Genetic variants occurring in the NAT2 coding region have been well-defined and are known to affect the enzyme activit
Externí odkaz:
https://doaj.org/article/3eae20c69c6d4ce1aad7b6ce9110551a
Autor:
Kyung U. Hong, Jonathan Q. Gardner, Mark A. Doll, Marcus W. Stepp, Daniel W. Wilkey, Frederick W. Benz, Jian Cai, Michael L. Merchant, David W. Hein
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1566-1573 (2022)
Previous studies have shown that inhibition or depletion of N-acetyltransferase 1 (NAT1) in breast cancer cell lines leads to growth retardation both in vitro and in vivo, suggesting that NAT1 contributes to rapid growth of breast cancer cells. To un
Externí odkaz:
https://doaj.org/article/14d38dbd1a6144afb9a6d281a22dfd77
Autor:
Kyung U. Hong, Jonathan Q. Gardner, Mark A. Doll, Marcus W. Stepp, Daniel W. Wilkey, Frederick W. Benz, Jian Cai, Michael L. Merchant, David W. Hein
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108634- (2022)
Arylamine N-acetyltransferase 1 (NAT1) is frequently upregulated in breast cancer. An unbiased analysis of proteomes of parental MDA-MB-231 breast cancer cells and two separate NAT1 knockout (KO) cell lines were performed. Among 4,890 proteins identi
Externí odkaz:
https://doaj.org/article/9640105bd1f2402aab174ae3aecdec59
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2066 (2023)
The endoplasmic reticulum (ER) is a multifunctional organelle playing a vital role in maintaining cell homeostasis, and disruptions to its functions can have detrimental effects on cells. Dysregulated ER stress and the unfolded protein response (UPR)
Externí odkaz:
https://doaj.org/article/0bfba422564e4e6ebc773b3dff54db4b
Autor:
Kyung U. Hong, Mark A. Doll, Angeliki Lykoudi, Raúl A. Salazar-González, Mariam R. Habil, Kennedy M. Walls, Alaa F. Bakr, Smita S. Ghare, Shirish S. Barve, Gavin E. Arteel, David W. Hein
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 1319-1330 (2020)
Recent reports suggest that arylamine N-acetyltransferases (NAT1 and/or NAT2) serve important roles in regulation of energy utility and insulin sensitivity. We investigated the interaction between diet (control vs. high-fat diet) and acetylator pheno
Externí odkaz:
https://doaj.org/article/8c2d5f97bfa94701b708cdfcf9c1ea40
Autor:
Joseph Brady Moore IV, David M Loeb, Kyung U. Hong, Poul H Sorensen, Timothy J Triche, David W Lee, Michael eBarbato, Robert John Arceci
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 3 (2015)
Developmental reprogramming techniques have been used to generate induced pluripotent stem (iPS) cells from both normal and malignant cells. The derivation of iPS cells from cancer has the potential to provide a unique scientific tool to overcome cha
Externí odkaz:
https://doaj.org/article/2178f01ae1234106af0d127b61d978e9
Publikováno v:
Archives of Toxicology. 97:1613-1626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3e602077e87803eebaefb237a49461
https://doi.org/10.1007/s00204-023-03488-2
https://doi.org/10.1007/s00204-023-03488-2
Publikováno v:
Toxicological Sciences. 190:158-172
Arylamine N-acetyltransferase 2 (NAT2) is well-known for its role in phase II metabolism of xenobiotics and drugs. More recently, genome wide association studies and murine models implicated NAT2 in regulation of insulin sensitivity and plasma lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afcac386e43169620159aa291052acb
https://doi.org/10.1093/toxsci/kfac103
https://doi.org/10.1093/toxsci/kfac103
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00d2f6f8812599bfa35417dd1063c3a8
https://doi.org/10.1007/s00432-022-04436-w
https://doi.org/10.1007/s00432-022-04436-w