Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kyung Kwon Lee"'
Autor:
Mitsuhiro Kayama, Shin Yonehara, Mina Kikuchi, Kyung-Kwon Lee, Shunsuke Kuroki, Shota Sakaguchi
Publikováno v:
Journal of Biological Chemistry. 287:41165-41173
Caspase-8 has an important role as an initiator caspase during death receptor-mediated apoptosis. Moreover, it has been reported to contribute to the regulation of cell fate in various types of cells including T-cells. In this report, we show that ca
Autor:
Dae-Sik Lim, Min Sup Song, Chang Rak Im, Mi Sun Jin, Shin Yonehara, Joo Hyun Lee, Jie-Oh Lee, Kyung Kwon Lee, Hyun Jung Oh, Su Jung Song
Publikováno v:
Cancer Research. 66:2562-2569
Mammalian sterile 20–like kinase 1 (Mst1) is activated by both caspase-mediated cleavage and phosphorylation in response to apoptotic stimuli, including Fas ligation. Here, we examined the possible role of the tumor suppressor RASSF1A in Mst1 activ
Publikováno v:
Journal of Biological Chemistry. 276:19276-19285
The human serine/threonine kinase, mammalian STE20-like kinase (MST), is considerably homologous to the budding yeast kinases, SPS1 and STE20, throughout their kinase domains. The cellular function and physiological activation mechanism of MST is unk
Autor:
Shin Yonehara, Kyung-Kwon Lee, Masao Murakawa, Kazuhiro Sakamaki, Seiichi Kawashima, Shu Takahashi, Satoshi Tsubuki
Publikováno v:
Journal of Biological Chemistry. 273:19160-19166
We purified a protein of 32 kDa from human thymoma HPB-ALL cells that was co-purified with a catalytic fragment of MST (mammalian STE-20-like), a kinase of the STE20 family, which is proteolytically activated by caspase in apoptosis (Lee, K.-K., Mura
Autor:
Seiichi Kawashima, Masao Murakawa, Kazuhiro Sakamaki, Shin Yonehara, Satoshi Tsubuki, Kyung-Kwon Lee, Eisuke Nishida
Publikováno v:
Oncogene. 16:3029-3037
The Fas system has been extensively investigated as a model of apoptosis and the caspase cascade has been shown to be a characteristic mechanism of signaling of apoptosis. We have identified and purified a kinase that was activated after the stimulat
Autor:
Richard W. Moyer, Hirokazu Hirata, Kokichi Yamamoto, Toshiro Okazaki, Hirofumi Sawai, Shuji Kishi, Peter W. Mesner, Kyung-Kwon Lee, Minoru Okuma, Shin Yonehara, Masataka Sasada, Atsushi Takahashi, Peter C. Turner, Yuzuru Imai
Publikováno v:
Oncogene. 14:2741-2752
The activation of multiple interleukin-1beta converting enzyme-related proteases (caspases) in apoptotic mammalian cells raises questions as to whether the multiple active caspases have distinct roles in apoptotic execution as well as how these prote
Autor:
Shin Yonehara, Kyung-Kwon Lee
The transcriptional coactivator Yes-associated protein (YAP) has been implicated in tumorigenesis by regulating cell proliferation and apoptosis. YAP interacts with the transcription factor TEAD and is essential in mediating TEAD-dependent gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba267122247ad6e5300c3689e1381f5
https://europepmc.org/articles/PMC3308740/
https://europepmc.org/articles/PMC3308740/
Publikováno v:
Journal of the Korean Ophthalmological Society. 56:1104
Autor:
Masataka Sasada, Takashi Uchiyama, Yasuko Kotone-Miyahara, Kouhei Yamashita, Atsushi Takahashi, Shin Yonehara, Kyung-Kwon Lee
Publikováno v:
Journal of leukocyte biology. 76(5)
Granulocyte macrophage-colony stimu- lating factor (GM-CSF) inhibits Fas-induced apoptosis of neutrophils. However, the exact step in the apo- ptotic pathway blocked by GM-CSF remained un- clear. Here, we found that pretreatment of neutro- phils with
Autor:
Naoya Tsurushita, Yukiko Gotoh, Hidetaka Kosako, Kyung-Kwon Lee, Eisuke Nishida, Yoshiko Akamatsu
Publikováno v:
Biochemistry. 35(40)
MAP kinase kinase (MAPKK) is a dual specificity protein kinase that phosphorylates and activates MAP kinase in vivo. In this study, four mouse monoclonal single-chain Fv (scFv) antibodies (Y1-6, Y1-7, Y3-6, and Y3-11) that can specifically bind to Xe