Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kyung Koo Kang"'
Publikováno v:
Toxicology and applied pharmacology. 410
Udenafil is a long-acting oral phosphodiesterase type 5 inhibitor used to treat erectile dysfunction which may also have beneficial effects on cardiovascular diseases. Udenafil is mainly biotransformed to the active metabolite N-dealkylated udenafil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84d816bd6a99df65d4653e0ec8e0921
https://pubmed.ncbi.nlm.nih.gov/33221319
https://pubmed.ncbi.nlm.nih.gov/33221319
Autor:
Tae Im Kim, Yu Mi Yang, Kyung Koo Kang, Eung Kweon Kim, Dong Min Shin, Hye Won Ji, Soonhong Park
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
DA-6034, a eupatilin derivative of flavonoid, has shown potent effects on the protection of gastric mucosa and induced the increases in fluid and glycoprotein secretion in human and rat corneal and conjunctival cells, suggesting that it might be cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddb92c9b3c2ff9ccaa36ca09bedf602
http://europepmc.org/articles/PMC3994308
http://europepmc.org/articles/PMC3994308
Publikováno v:
Drug Research. 64:563-568
To investigate the pathogenesis of hyperlipidemia-related erectile dysfunction and the effects of DA-8159, a new phosphodiesterase-5 inhibitor, on protein expression, we performed a proteomic analysis of differentially expressed proteins in the corpu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf410ef72247675ab2d4181f57d675c1
https://doi.org/10.1055/s-0033-1363994
https://doi.org/10.1055/s-0033-1363994
Publikováno v:
International Journal of Urology. Mar2005, Vol. 12 Issue 3, p299-304. 6p.
Publikováno v:
International Journal of Urology. 21:325-329
Objectives DA-8031 is a potent and selective serotonin transporter inhibitor developed for the treatment of premature ejaculation. The aim of the present study was to investigate the effects of DA-8031 on male sexual behavior in a rat model. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fabbdb3bd02035da737e8571c80037ef
https://doi.org/10.1111/iju.12256
https://doi.org/10.1111/iju.12256
Autor:
Jin Y. Lee, Jung Mogg Kim, Hyeyoung Kim, Do Young Yoo, Ho Joo Yoon, Su H. Ko, Jeehee Youn, Yeong Jeon Kim, Kyung Koo Kang, Jireh Jung, Seul Min Choi
Publikováno v:
Immunology. 137:98-113
5,7-Dihydroxy-3′,4′,6′-trimethoxyflavone (eupatilin), the active pharmacological ingredient from Artemisia asiatica Nakai (Asteraceae), is reported to have a variety of anti-inflammatory properties in intestinal epithelial cells. However, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e79bf289d4f9649d4a2854d8717325
https://doi.org/10.1111/j.1365-2567.2012.03618.x
https://doi.org/10.1111/j.1365-2567.2012.03618.x
Fertility Study of the New Pyrazolo-pyrimidinone Derivative DA-8159 for Erectile Dysfunction in Rats
Publikováno v:
Arzneimittelforschung. 54:179-186
DA-8159 (5-[2-propyloxy-5-(1-methyl-2-pyrrolidinylethylamidosulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidine-7-one, CAS 268203-93-6) is a new pyrazolopyrimidinone derivative for the treatment of erectile dysfunction. The te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e22a4a374cc2850c132969c6b11484
https://doi.org/10.1055/s-0031-1296956
https://doi.org/10.1055/s-0031-1296956
Autor:
Seul-Min Choi, Byoung-Ok Ahn, Kyung-Koo Kang, Moohi Yoo, Shin Jee-Hyun, Ju-Mi Kim, Chan-Ho Lee
Publikováno v:
Arzneimittelforschung. 59:641-646
The purpose of this study was to investigate the therapeutic efficacy of udenafil (CAS 268203-93-6), a phosphodiesterase type 5 (PDE5) inhibitor, on bile duct ligation (BDL)-induced portal hypertension. Udenafil was given orally to rats at dose level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::083e5b4e06feed3f8725163f3c1d4147
https://doi.org/10.1055/s-0031-1296453
https://doi.org/10.1055/s-0031-1296453
Autor:
Yeong-Jeon Kim, Joo Sung Kim, Jung Mogg Kim, Hyeyoung Kim, Seul-Min Choi, Kyung-Koo Kang, Do-Young Yoo, Nayoung Kim, SuHyuk Ko
Publikováno v:
Scandinavian Journal of Immunology. 74:253-263
DA-6034 is a synthetic derivative of eupatilin, a flavonoid with anti-inflammatory effects. The aim of this study was to investigate the effects of DA-6034 on the interactions between IκB kinase (IKK) and heat shock protein 90 (Hsp90), and activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a3aa503cf9c9363b0c31bb8d6d54f7
https://doi.org/10.1111/j.1365-3083.2011.02577.x
https://doi.org/10.1111/j.1365-3083.2011.02577.x
Publikováno v:
Current Eye Research. 35:165-175
To investigate the effect of DA-6034, 7-carboxymethyloxy-3',4',5-trimethoxy flavone, in experimentally-induced inflammatory dry eye in rabbit. In addition, to elucidate the mechanism of DA-6034, we evaluated the mitogen-activated protein kinase (MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56af233e6b708a1fdc8d3ed837c0741b
https://doi.org/10.3109/02713680903453494
https://doi.org/10.3109/02713680903453494