Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Kyung H Choi"'
Autor:
Wenshuo Zhou, Michael Woodson, Biswas Neupane, Fengwei Bai, Michael B Sherman, Kyung H Choi, Girish Neelakanta, Hameeda Sultana
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006764 (2018)
Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the vertebrate host are poorly understood. In this study, we show for the first time that a cell line from medically important arthropods, such as ticks, secretes ext
Externí odkaz:
https://doaj.org/article/e38ce0540a6b42aeb5f460528cb3c817
Autor:
Valerie J Klema, Krishna Mohan Sepuru, Nadia Füllbrunn, Tierra R Farris, Paige S Dunphy, Jere W McBride, Krishna Rajarathnam, Kyung H Choi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194891 (2018)
Ehrlichia chaffeensis, the causative agent of human monocytotropic ehrlichiosis, secretes several effector proteins that bind host DNA to modulate host gene expression. The tandem repeat protein 120 (TRP120), one of the largest effector proteins, has
Externí odkaz:
https://doaj.org/article/323364a3ba5543abb73cfd9c9cb18991
Autor:
Valerie J Klema, Mengyi Ye, Aditya Hindupur, Tadahisa Teramoto, Keerthi Gottipati, Radhakrishnan Padmanabhan, Kyung H Choi
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005451 (2016)
Flavivirus nonstructural protein 5 (NS5) consists of methyltransferase (MTase) and RNA-dependent RNA polymerase (RdRp) domains, which catalyze 5'-RNA capping/methylation and RNA synthesis, respectively, during viral genome replication. Although the c
Externí odkaz:
https://doaj.org/article/77e014d574f84f2891aad1e42679194f
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract During HIV infection, specific RNA-protein interaction between the Rev response element (RRE) and viral Rev protein is required for nuclear export of intron-containing viral mRNA transcripts. Rev initially binds the high-affinity site in ste
Externí odkaz:
https://doaj.org/article/f858a5657fb84fe398c755927e4afd6d
Autor:
Keerthi Gottipati, Nicolas Ruggli, Markus Gerber, Jon-Duri Tratschin, Matthew Benning, Henry Bellamy, Kyung H Choi
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003704 (2013)
Pestiviruses express their genome as a single polypeptide that is subsequently cleaved into individual proteins by host- and virus-encoded proteases. The pestivirus N-terminal protease (N(pro)) is a cysteine autoprotease that cleaves between its own
Externí odkaz:
https://doaj.org/article/ebdd45b1b6d74122aa1b899f2fb977b9
Publikováno v:
Antiviral research.
Flaviviruses are important human pathogens and include dengue (DENV), West Nile (WNV), Yellow fever virus (YFV), Japanese encephalitis (JEV) and Zika virus (ZIKV). DENV, transmitted by mosquitoes, causes diseases ranging in severity from mild dengue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0beefa4f53c4e546d915e60092705672
https://pubmed.ncbi.nlm.nih.gov/36586467
https://pubmed.ncbi.nlm.nih.gov/36586467
Autor:
William K. Russell, Hongjie Xia, Christian G. Noble, Mark A. White, Pei Yong Shi, Luis Marcelo F. Holthauzen, Kyung H. Choi, Jing Zou, Xuping Xie
Publikováno v:
Proc Natl Acad Sci U S A
Dengue virus (DENV) was designated as a top 10 public health threat by the World Health Organization in 2019. No clinically approved anti-DENV drug is currently available. Here we report the high-resolution cocrystal structure (1.5 Å) of the DENV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d9bc1f92f9f8dd2981ad0e901c1791
https://doi.org/10.1073/pnas.2003056117
https://doi.org/10.1073/pnas.2003056117
Publikováno v:
Virology
Alphavirus genome replication is carried out by the viral replication complex inside modified membrane structures called spherules. The viral nonstructural protein 1 (nsP1) is the only membrane-associated protein that anchors the replication complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c5b6b512a6f45f8974c55dc3055f62
https://doi.org/10.1016/j.virol.2020.02.006
https://doi.org/10.1016/j.virol.2020.02.006
Publikováno v:
International Journal of Energy Research. 44:7035-7046
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13961f5e79437aa5b1282dc9a712d523
https://doi.org/10.1002/er.5371
https://doi.org/10.1002/er.5371
Autor:
Kyung H. Choi, Priyank Maindola, Michal R. Szymanski, Cecile Bussetta, Mark A. White, Emilio Reyes-Aldrete, Wlodzimierz Bujalowski, Marc C. Morais, Erik Dill, Geoffrey S Diemer
Publikováno v:
Viruses, Vol 13, Iss 15, p 15 (2021)
Viruses
Volume 13
Issue 1
Viruses
Volume 13
Issue 1
Double-stranded DNA viruses package their genomes into pre-assembled protein procapsids. This process is driven by macromolecular motors that transiently assemble at a unique vertex of the procapsid and utilize homomeric ring ATPases to couple genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eb58a07602c15c9e30fb06170ec404
https://www.mdpi.com/1999-4915/13/1/15
https://www.mdpi.com/1999-4915/13/1/15