Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kyung Cheul Shin"'
Autor:
Sang Mun Han, Eun Seo Park, Jeu Park, Hahn Nahmgoong, Yoon Ha Choi, Jiyoung Oh, Kyung Min Yim, Won Taek Lee, Yun Kyung Lee, Yong Geun Jeon, Kyung Cheul Shin, Jin Young Huh, Sung Hee Choi, Jiyoung Park, Jong Kyoung Kim, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Adipose tissue invariant natural killer T (iNKT) cells are a crucial cell type for adipose tissue homeostasis in obese animals. However, heterogeneity of adipose iNKT cells and their function in adipocyte turnover are not thoroughly understo
Externí odkaz:
https://doaj.org/article/d3ca452b89c1433e85b4e587340d3c1d
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte
Externí odkaz:
https://doaj.org/article/c719b3a3e9594fb9a44b17d3954cfdae
Autor:
Kyung Cheul Shin, Injae Hwang, Sung Sik Choe, Jeu Park, Yul Ji, Jong In Kim, Gha Young Lee, Sung Hee Choi, Jianhong Ching, Jean-Paul Kovalik, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitati
Externí odkaz:
https://doaj.org/article/67c72e112e95430fb6d3dc4e4e0e79d3
Autor:
Kyung Cheul Shin, Jin Young Huh, Yul Ji, Ji Seul Han, Sang Mun Han, Jeu Park, Hahn Nahmgoong, Won Taek Lee, Yong Geun Jeon, Bohyeon Kim, Chanyoon Park, Heonjoong Kang, Sung Sik Choe, Jae Bum Kim
Publikováno v:
Cell Reports. 41:111806
In mammals, brown adipose tissue (BAT) is specialized to conduct non-shivering thermogenesis for survival under cold acclimation. Although emerging evidence suggests that lipid metabolites are essential for heat generation in cold-activated BAT, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4567cea930ae8f29dd712072e21d663c
https://doi.org/10.1016/j.celrep.2022.111806
https://doi.org/10.1016/j.celrep.2022.111806
Autor:
Jeu Park, Do Hoon Lee, Seokjin Ham, Jiyoung Oh, Jung-Ran Noh, Yun Kyung Lee, Yoon Jeong Park, Gung Lee, Sang Mun Han, Ji Seul Han, Ye Young Kim, Yong Geun Jeon, Han Nahmgoong, Kyung Cheul Shin, Sung Min Kim, Sung Hee Choi, Chul-Ho Lee, Jiyoung Park, Tae Young Roh, Sun Kim, Jae Bum Kim
Publikováno v:
Nature metabolism. 4(7)
DNA methylation is a crucial epigenetic modification in the establishment of cell-type-specific characteristics. However, how DNA methylation is selectively reprogrammed at adipocyte-specific loci during adipogenesis remains unclear. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfaff0d8fceb9a2b779488f4afe2dce
https://pubmed.ncbi.nlm.nih.gov/35788760
https://pubmed.ncbi.nlm.nih.gov/35788760
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature communications. 13(1)
Thermogenic adipocytes generate heat to maintain body temperature against hypothermia in response to cold. Although tight regulation of thermogenesis is required to prevent energy sources depletion, the molecular details that tune thermogenesis are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d6938eb922a3d1a71c1314386b6d63
https://pubmed.ncbi.nlm.nih.gov/35672324
https://pubmed.ncbi.nlm.nih.gov/35672324
Autor:
Assim A. Alfadda, Injae Hwang, Kyuri Jo, Yoon Jeong Park, Jeu Park, Yul Ji, Sujin Suk, Jason K. Kim, Hye Lim Noh, Jae Bum Kim, Sojeong Ka, Sun Kim, Kyung Cheul Shin, Jong In Kim, Yong Geun Jeon, Sung Sik Choe
Publikováno v:
Proceedings of the National Academy of Sciences. 116:11936-11945
Accumulating evidence suggests that subcutaneous and visceral adipose tissues are differentially associated with metabolic disorders. In obesity, subcutaneous adipose tissue is beneficial for metabolic homeostasis because of repressed inflammation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fa37bcbe3486db9149815db7b0361f2
https://doi.org/10.1073/pnas.1822067116
https://doi.org/10.1073/pnas.1822067116
Autor:
Kyung Cheul Shin
Publikováno v:
Molecules & Cells (Elsevier B.V); Jun2023, Vol. 46 Issue 6, p345-347, 3p
Autor:
Yong Geun Jeon, Jiyoung Oh, Sang Mun Han, Jiyoung Park, Jin Young Huh, Kyung Cheul Shin, Jeu Park, Jong In Kim, Jae Bum Kim, Sung Sik Choe
Publikováno v:
Genes Dev
In obesity, adipose tissue undergoes dynamic remodeling processes such as adipocyte hypertrophy, hypoxia, immune responses, and adipocyte death. However, whether and how invariant natural killer T (iNKT) cells contribute to adipose tissue remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4152e02a062fbaef7918ceca503dad4d
https://europepmc.org/articles/PMC6942052/
https://europepmc.org/articles/PMC6942052/
Autor:
Jean-Paul Kovalik, Sung Sik Choe, Sung Hee Choi, Jae Bum Kim, Kyung Cheul Shin, Yul Ji, Gha Young Lee, Jong In Kim, Jianhong Ching, Injae Hwang, Jeu Park
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
NATURE COMMUNICATIONS(8)
Nature Communications
NATURE COMMUNICATIONS(8)
Nature Communications
Obesity is closely associated with increased adipose tissue macrophages (ATMs), which contribute to systemic insulin resistance and altered lipid metabolism by creating a pro-inflammatory environment. Very low-density lipoprotein receptor (VLDLR) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5ce0f9b2306e10a992c3bfe12c665c
https://doaj.org/article/67c72e112e95430fb6d3dc4e4e0e79d3
https://doaj.org/article/67c72e112e95430fb6d3dc4e4e0e79d3