Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kyung Ah Choi"'
Autor:
Wonjin Yun, Kyung-Ah Choi, Insik Hwang, Jie Zheng, Minji Park, Wonjun Hong, Ah-Young Jang, Jeong Hee Kim, Wonji Choi, Dae-Sung Kim, In Yong Kim, Yong Jun Kim, Ying Liu, Byung Sun Yoon, Gyuman Park, Gwonhwa Song, Sunghoi Hong, Seungkwon You
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract The generation of human oligodendrocyte progenitor cells (OPCs) may be therapeutically valuable for human demyelinating diseases such as multiple sclerosis. Here, we report the direct reprogramming of human somatic cells into expandable indu
Externí odkaz:
https://doaj.org/article/38e6a2349c0b4d4da6d467d01067452c
Autor:
Seung-ick Oh, Hyesun Jeong, Hang-soo Park, Kyung-Ah Choi, Insik Hwang, Jiyun Lee, Jeonghee Cho, Sunghoi Hong
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 1303-1313 (2020)
Cancer stem cells (CSCs) have been implicated in the growth and progression of several types of human cancer. The technology to derive and establish CSCs in vitro could be a critical tool for understanding cancer and developing new therapeutic target
Externí odkaz:
https://doaj.org/article/d3a5080b476542f7af630be12e4bef3c
Autor:
Insik Hwang, Kyung-Ah Choi, Hang-Soo Park, Hyesun Jeong, Jeong-Ok Kim, Ki-Cheon Seol, Han-Jin Kwon, In-Hyun Park, Sunghoi Hong Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Several types of hair loss result from the inability of hair follicles to initiate the anagen phase of the hair regeneration cycle. Modulating signaling pathways in the hair follicle niche can stimulate entry into the anagen phase. Despite much effor
Externí odkaz:
https://doaj.org/article/da41ad66929848039cb5b76e9fa6e7a3
Autor:
Insik Hwang, Suk-Chan Hahm, Kyung-Ah Choi, Sung-Ho Park, Hyesun Jeong, Ji-Hye Yea, Junesun Kim Ph.D., Sunghoi Hong Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Neuropathic pain following spinal cord injury (SCI) is a devastating disease characterized by spontaneous pain such as hyperalgesia and allodynia. In this study, we investigated the therapeutic potential of ESC-derived spinal GABAergic neurons to tre
Externí odkaz:
https://doaj.org/article/531973f610904c93961d6decf9346c7a
Autor:
Insik Hwang, Hyesun Jeong, Sunghoi Hong, Seung Ick Oh, Kyung Ah Choi, Ji Yun Lee, Hang-Soo Park, Jeonghee Cho
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology. 48:1303-1313
Cancer stem cells (CSCs) have been implicated in the growth and progression of several types of human cancer. The technology to derive and establish CSCs in vitro could be a critical tool for under...
Autor:
Seung-ick Oh, Hang-soo Park, Insik Hwang, Han-kyul Park, Kyung-Ah Choi, Hyesun Jeong, Suhng Wook Kim, Sunghoi Hong
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neur
Externí odkaz:
https://doaj.org/article/fb9b6191f7024b22bb3cd36d46baf7b9
Autor:
Yeonju Bae, Jae Yong Park, Yeonho Choi, Kyung Ah Choi, Hang-Soo Park, Sunghoi Hong, Hyosung Kwon, Jewon Yu
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology. 46:1114-1122
Direct conversion is a powerful approach to safely generate mature neural lineages with potential for treatment of neurological disorders. Astrocytes play a crucial role in neuronal homeostasis and their dysfunctions contribute to several neurodegene
Publikováno v:
Methods. 133:104-112
Therapeutic approaches based on stem cells have received considerable attention as potential treatments for Huntington's disease (HD), which is a fatal, inherited neurodegenerative disorder, caused by progressive loss of GABAergic medium spiny neuron
Autor:
Kyung-Ah Choi
Publikováno v:
BUL GYO HAK BO. 79:9-32
Publikováno v:
Biochemical and biophysical research communications. 518(2)
UV-induced skin damage is involved in ROS overproduction and the overexpression of matrix metalloproteinases (MMPs), which are inhibited by TIMPs (tissue inhibitor of neural stem cells (NSCs)). These proteins may be associated with skin regeneration