Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kyung Ae Ji"'
Autor:
So-Young Hwang, Jae-Seob Jung, Tae-Hyun Kim, Soo-Jeong Lim, Eok-Soo Oh, Joo-Young Kim, Kyung-Ae Ji, Eun-Hye Joe, Kwan-Ho Cho, Inn-Oc Han
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 3, Pp 457-467 (2006)
The aim of this study was to investigate the role of microglia in radiation-induced astrocyte gliosis. We found that a single dose of 15 Gy radiation to a whole rat brain increased immunostaining of glial fibrillary acidic protein in astrocytes 6 h l
Externí odkaz:
https://doaj.org/article/66c4cca5f21e4112849ca98fc12e5928
Publikováno v:
Glia. 56:1039-1047
Brain inflammation is a suggested risk factor for neurodegenerative disease. Interestingly, severe inflammation in the substantia nigra pars compacta (SNpc) accelerates the onset and progression of Parkinson's disease. In this study, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3baf97cc746d79ef451ad1e5303fd0
https://doi.org/10.1002/glia.20677
https://doi.org/10.1002/glia.20677
Autor:
Joo-Young Kim, Kwan Ho Cho, Kyung Ae Ji, Inn-Oc Han, So-Young Hwang, Tae Hyun Kim, Soo Jeong Lim, Jae Seob Jung, Eok Soo Oh, Eun Hye Joe
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 3, Pp 457-467 (2006)
The aim of this study was to investigate the role of microglia in radiation-induced astrocyte gliosis. We found that a single dose of 15 Gy radiation to a whole rat brain increased immunostaining of glial fibrillary acidic protein in astrocytes 6 h l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71f5c97302dd27b4a757f1c97288534
https://doi.org/10.1016/j.nbd.2005.08.006
https://doi.org/10.1016/j.nbd.2005.08.006
Publikováno v:
Biochemical and Biophysical Research Communications. 328:595-600
The Janus kinase (JAK) and signal transducers and activators of transcription (STAT) signal cascades are major pathways that mediate the inflammatory functions of interferon-gamma (IFN-gamma), an important pro-inflammatory cytokine. Therefore, regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d65f06e3b414692cee3f063db54cce
https://doi.org/10.1016/j.bbrc.2005.01.025
https://doi.org/10.1016/j.bbrc.2005.01.025
Autor:
Jae Hong Kim, Ilo Jou, Woo Hyuck Choi, Eun Hye Joe, Hye Jin You, Eun Jung Park, Inn-Oc Han, Kyung Ae Ji, Sae Bom Jeon
Publikováno v:
The Journal of Immunology. 173:5697-5703
Rac1 GTPase is implicated as a signaling mediator in various cellular events. In this study, we show that Rac1 contributes to IFN-γ-induced inflammatory responses in rat astrocytes. We revealed that IFN-γ rapidly stimulated activation of Rac1 in C6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169d8891686e6afcc742acfef9d2cb0f
https://doi.org/10.4049/jimmunol.173.9.5697
https://doi.org/10.4049/jimmunol.173.9.5697
Autor:
Myung-Soon Yang, Eun-Hye Joe, Ilo Jou, Seung-Hee Kang, Kyung-Ae Ji, Kyoung-Jin Min, Hey-Kyeong Jeong
Publikováno v:
Glia. 55(15)
Generally, it has been accepted that microglia play important roles in brain inflammation. However, recently several studies suggested possible infiltration of blood neutrophils and monocytes into the brain. To understand contribution of microglia an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b7dd1df2ffa51c9894f6461b8edb26
https://pubmed.ncbi.nlm.nih.gov/17823975
https://pubmed.ncbi.nlm.nih.gov/17823975
Autor:
Kyung-Ae Ji, Ilo Jou, Seung U. Kim, Byung-Kwan Jin, Myung-Soon Yang, Sae-Bom Jeon, Eun-Hye Joe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(2)
Brain inflammation has recently attracted widespread interest because it is a risk factor for the onset and progression of brain diseases. In this study, we report that cyclooxygenase-2 (COX-2) plays a key role in the resolution of brain inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40ef217366270077bba8303d77cce84
https://pubmed.ncbi.nlm.nih.gov/16818793
https://pubmed.ncbi.nlm.nih.gov/16818793
Autor:
Kyoung-Jin Min, Ho Kim, Woo-Hyuck Choi, Myung-Soon Yang, Minho Shong, Ilo Jou, Sae-Bom Jeon, Kyung-Ae Ji, Eun-Hye Joe
Publikováno v:
Biochemical and biophysical research communications. 329(1)
The anti-inflammatory effect of retinoic acid (RA) has been investigated for several decades. However, the underlying mechanisms responsible for this effect are largely unknown. In this study, we demonstrate that 9-cis-RA (cRA) and all-trans-RA (tRA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f3b1d68c3bed38a7a075bad6542407
https://pubmed.ncbi.nlm.nih.gov/15721283
https://pubmed.ncbi.nlm.nih.gov/15721283
Publikováno v:
Glia. 48(3)
Microglia, the major immune effector cells in the central nervous system, are activated when the brain suffers injury. A number of studies indicate that gangliosides activate microglia. However, the signaling mechanisms involved in microglial activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438b1bbabf973dd3b9697037cfab1f7e
https://pubmed.ncbi.nlm.nih.gov/15390122
https://pubmed.ncbi.nlm.nih.gov/15390122
Publikováno v:
Glia. 48(2)
Previously we have reported that thrombin induces inflammatory mediators in brain glial cells (Ryu et al. 2000. J Biol Chem 275:29955). In the present study, we found that thrombin induced a negative regulator of a cytokine signaling molecule, cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cdbbf56f94df7ce8b6d38ad0dcda08
https://pubmed.ncbi.nlm.nih.gov/15378659
https://pubmed.ncbi.nlm.nih.gov/15378659