Force tuning through regulation of clathrin-dependent integrin endocytosis

Autor: Alexander Kyumurkov, Anne-Pascale Bouin, Mathieu Boissan, Sandra Manet, Francesco Baschieri, Mathilde Proponnet-Guerault, Martial Balland, Olivier Destaing, Myriam Régent-Kloeckner, Claire Calmel, Alice Nicolas, François Waharte, Philippe Chavrier, Guillaume Montagnac, Emmanuelle Planus, Corinne Albiges-Rizo

Publikováno v: Journal of Cell Biology
Journal of Cell Biology, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩
Journal of Cell Biology, Rockefeller University Press, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩

International audience; Integrin endocytosis is essential for many fundamental cellular processes. Whether and how the internalization impacts cellular mechanics remains elusive. Whereas previous studies reported the contribution of the integrin acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe61a3b2c47dad1962707fc3ffa2406
https://hal.science/hal-03834328/file/jcb_202004025.pdf

Tension cellulaire et trafic des intégrines. (French)

Autor: Bouin, Anne-Pascale, Kyumurkov, Alexander, Planus, Emmanuelle, Albiges-Rizo, Corinne

Publikováno v: Médecine Sciences; aou/sep2023, Vol. 39 Issue 8/9, p597-599, 3p

Rôle d'ICAP-1 dans la régulation de la mécanosensibilité et de la contractilité des cellules ostéoblastiques via la dynamique des intégrins

Autor: Kyumurkov, Alexander

Publikováno v: Cellular Biology. Université Grenoble Alpes, 2017. English. ⟨NNT : 2017GREAV057⟩

ICAP-1 is involved in integrin dynamics and force generation by controlling integrin endocytosis through nm23-dependent scission of endocytic chlatrin coated pits.ICAP-1 has been identified as a specific partner of b1 integrin (Degani et al., 2002; Z

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::29ccd3e1326de047020809deb32f8528
https://tel.archives-ouvertes.fr/tel-02141523/document

ICAP-1 monoubiquitination coordinates matrix density and rigidity sensing for cell migration through ROCK2- MRCKα balance

Autor: Eva Faurobert, Ingrid Bourrin-Reynard, Anne-Pascale Bouin, Christiane Oddou, Myriam Régent-Kloeckner, Martial Balland, Anne-Sophie Ribba, Corinne Albiges-Rizo, Alexander Kyumurkov, Henri-Noël Fournier, Emmanuelle Planus, Sandra Manet-Dupé

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2017, 130 (3), pp.626-636. ⟨10.1242/jcs.200139⟩
Journal of Cell Science, 2017, 130 (3), pp.626-636. ⟨10.1242/jcs.200139⟩

International audience; Cell migration is a complex process requiring density and rigidity sensing of the microenvironment to adapt cell migratory speed through focal adhesion and actin cytoskeleton regulation. ICAP-1 (also known as ITGB1BP1), a β1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b043ded03aaa26a4620a8b5c41fe990
https://doi.org/10.1242/jcs.200139

Surface chemistry study of the interactions of benzalkonium chloride with films of meibum, corneal cells lipids, and whole tears

Autor: Albena Jordanova, Alexander Kyumurkov, Slavyana Ivanova, Georgi As. Georgiev, Elena Kutsarova, Rumen Krastev, Zdravko Lalchev, Norihiko Yokoi, Krassimir Koev

Publikováno v: Investigative ophthalmologyvisual science. 52(7)

PURPOSE To perform a surface chemistry study of the interactions between benzalkonium chloride (BAC), a common preservative used in ophthalmic formulations, and tear film (TF) constituents. METHODS The interactions between BAC and human tears, meibum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809ecb0a45c3883a1dbc31fc0eeea758
https://pubmed.ncbi.nlm.nih.gov/21474774