Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kyu-Hyuk Cho"'
Autor:
Hyo-Seon Yang, Soonjin Kwon, Jinsoo Lee, Chang-Woo Song, Young-Beom Kim, Jae-Woo Cho, Jeong-Doo Her, Kyu-Hyuk Cho, Kyuhong Lee, Soo Nam Kim
Publikováno v:
Toxicological Research
Many studies have reported that bleomycin, anti-cancer drug, induces pulmonary fibrosis as a side effect. However, few investigations have focused on the dose-response effects of bleomycin on pulmonary fibrosis. Therefore, in the present study, we in
Autor:
Jae Hyuck Sung, Jin Sung Kim, Mi Jin Yang, Kyu Hyuk Cho, Il Je Yu, Hyeon Yeong Kim, Chae Woong Lim, Young Su Yang, Chang-Woo Song, Jung Sun Yang, Yong Hyun Chung
Publikováno v:
Inhalation Toxicology. 21:337-346
Previous studies on welding-fume-induced lung fibrosis have indicated that recovery is possible when the degree of exposure is short-term and moderate. However, this study investigated the recovery after recurrent exposure to welding fumes, as welder
Publikováno v:
Toxicological Research
Validation specifies and coordinates all relevant activities to ensure compliance with good laboratory practices (GLP) according to suitable international standards. This includes validation activities of past, present and future for the best possibl
Autor:
Young-Su, Yang, Mi-Jin, Yang, Kyu-Hyuk, Cho, Kyuhong, Lee, Yong-Bum, Kim, Jin-Sung, Kim, Myung-Gyun, Kang, Chang-Woo, Song
Publikováno v:
Toxicological Research
Allergic asthma is a worldwide public health problem and a major socioeconomic burden disease. It is a chronic inflammatory disease marked by airway eosinophilia and goblet cell hyperplasia with mucus hypersecretion. Mouse models have proven as a val
Autor:
Kyuhong Lee, Young-Su Yang, Mi-Jin Yang, Chang-Woo Song, Yong-Bum Kim, Kyu-Hyuk Cho, Jeong-Doo Heo
Publikováno v:
Toxicological Research
Abstrqact The single intratracheal instillation (ITI) of bleomycin (BLM) is a widely used method for inducing experimental pulmonary fibrosis in rat model. In the present study, pulmonary function tests (PFTs) of tidal volume (VT), minute volume (VM)
Publikováno v:
Toxicological Research
N-ethyl-N-nitrosoures (ENU) is effective in inducing hypermorphic mutation as well as hypomorphic and antimorphic mutations. Therefore, this mutagen is used to the production of mutant in the mice. In order to perform an effective ENU mutagenesis usi
Autor:
Kyu Hyuk Cho, Yang Seok Oh, Sung Joo Kim Yoon, Sang Seop Han, Seok Joo Yoon, Chang-Woo Song, Jong Bok Yoon, Dal Sun Cha, YoonYi Nam, Jun-Gyo Suh, Jeong Ki Kim, Jae-Woo Cho
Publikováno v:
Genomics. 87(4):520-526
A novel autosomal recessive mutant was produced using N-ethyl-N-nitrosourea mutagenesis. The characteristics of the mutant mice included progressive irreversible hair loss within a month of birth, wrinkled skin, and long curved nails. Linkage analysi
Autor:
Heung-Sik Seo, Hee-Jin Yu, Young-Su Yang, Kyuhong Lee, Chang-Woo Song, Soonjin Kwon, Jinsoo Lee, Jeongah Song, Seong-Jin Choi, Byoung-Seok Lee, Kyu-Hyuk Cho, Jeong-Doo Heo
Publikováno v:
Toxicological Research
tert-Butyl acetate (TBAc) is an organic solvent, which is commonly used in architectural coatings and industrial solvents. It has recently been exempted from the definition of a volatile organic compound (VOC) by the Air Resources Board (ARB) . Since
Autor:
Kyu-Hyuk Cho, Kyuhong Lee, Jeong-Doo Heo, Hyo-Seon Yang, Chang-Woo Song, Jeongah Song, Kyung Jin Jung, Soonjin Kwon, Jinsoo Lee
Publikováno v:
Toxicological Research
Bronchoalveolar lavage (BAL) is a useful tool in researches and in clinical medicine of lung diseases because the BAL fluid contains biochemical and cytological indicators of the cellular response to infection, drugs, or toxicants. However, the varia
Autor:
Yeun Jung Kim, Han Sung Jung, Chang-Woo Song, Jae-Woo Cho, Jae-Young Kim, Kyu Hyuk Cho, Min Jung Lee
Publikováno v:
Current eye research. 34(5)
Purpose: This study analyzed genes associated with the morphology and regulation of ethylnitrosourea (ENU)-induced cataract mouse. Materials and Methods: Immunohistochemistry analysis using anti-crystallins and PCNA antibody revealed that the localiz