Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Kyu Y Rhee"'
Autor:
Christopher S Williams, Emily J Gallagher, Don C Rockey, Olujimi A Ajijola, Patrick J Hu, Barbara I Kazmierczak, Christopher D Kontos, Jatin M Vyas, Mone Zaidi, Kyu Y Rhee
Publikováno v:
eLife, Vol 12 (2023)
The growing complexities of clinical medicine and biomedical research have clouded the career path for physician-scientists. In this perspective piece, we address one of the most opaque career stage transitions along the physician-scientist career pa
Externí odkaz:
https://doaj.org/article/4ab20f802ff8445ba89b147766a77ea1
Autor:
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy Rock
Publikováno v:
eLife, Vol 12 (2023)
Cyclic AMP (cAMP) is a ubiquitous second messenger that transduces signals from cellular receptors to downstream effectors. Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, devotes a considerable amount of coding capacity to p
Externí odkaz:
https://doaj.org/article/fe201b0981a543b4b8b62123b421ec24
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008434 (2019)
Phosphohexomutase superfamily enzymes catalyze the reversible intramolecular transfer of a phosphoryl moiety on hexose sugars. Bacillus subtilis phosphoglucomutase PgcA catalyzes the reversible interconversion of glucose 6-phosphate (Glc-6-P) and glu
Externí odkaz:
https://doaj.org/article/e6a095a1afb24ffc9934fcc5303caa7f
Autor:
Irnov Irnov, Zhe Wang, Nicholas D Jannetty, Julian A Bustamante, Kyu Y Rhee, Christine Jacobs-Wagner
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006978 (2017)
To achieve robust replication, bacteria must integrate cellular metabolism and cell wall growth. While these two processes have been well characterized, the nature and extent of cross-regulation between them is not well understood. Here, using classi
Externí odkaz:
https://doaj.org/article/a68c5e9e95a9453183d34ff14df3bccc
Autor:
Elizabeth L Alexander, Susana Gardete, Haim Y Bar, Martin T Wells, Alexander Tomasz, Kyu Y Rhee
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97137 (2014)
Intermediate (VISA-type) vancomycin resistance in Staphylococcus aureus has been associated with a range of physiologic and genetic alterations. Previous work described the emergence of VISA-type resistance in two clonally-distinct series of isolates
Externí odkaz:
https://doaj.org/article/31465233d0e34b13bc0d14ddebd013a3
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003116 (2013)
Mycobacterium tuberculosis (Mtb) is thought to preferentially rely on fatty acid metabolism to both establish and maintain chronic infections. Its metabolic network, however, allows efficient co-catabolism of multiple carbon substrates. To gain insig
Externí odkaz:
https://doaj.org/article/2d1334429efb479ea15a92a3654d9ba7
Autor:
Scott A Weisenberg, Jose R Mediavilla, Liang Chen, Elizabeth L Alexander, Kyu Y Rhee, Barry N Kreiswirth, Stephen G Jenkins
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45141 (2012)
BACKGROUND: We performed this study 1) to determine the prevalence of community-associated extended spectrum beta-lactamase producing Enterobacteriaceae (ESBLPE) colonization and infection in New York City (NYC); 2) to determine the prevalence of new
Externí odkaz:
https://doaj.org/article/1966f17a23b443a2aa03b8730f9b7573
Autor:
Scott A Weisenberg, Audrey N Schuetz, Elizabeth L Alexander, Brain Eiss, Maryam Behta, Lisa Saiman, Davise H Larone, Stephen G Jenkins, Kyu Y Rhee
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28566 (2011)
Acinetobacter baumannii is an increasingly multidrug-resistant (MDR) cause of hospital-acquired infections, often associated with limited therapeutic options. We investigated A. baumannii isolates at a New York hospital to characterize genetic relate
Externí odkaz:
https://doaj.org/article/1a55aaeaf9694a7798e5f720101fddb5
Autor:
TuAnh Ngoc Huynh, David S. Stevenson, William J.B. Vincent, Kyu Y. Rhee, Krizia M. Perez-Medina, Kimberly V. Gutierrez, Daniel Amador-Noguez, John-Demian Sauer, Joseph P. Dillard, Hans B. Smith, Katherine A. Black, Daniel A. Pensinger
Publikováno v:
mBio. 14
The cytosol of eukaryotic host cells is an intrinsically hostile environment for bacteria. Understanding how cytosolic pathogens adapt to and survive in the cytosol is critical to developing novel therapeutic interventions for these pathogens. The cy
Autor:
Victoria M. Schneider, Joseph E. Visone, Chantal T. Harris, Francesca Florini, Evi Hadjimichael, Xu Zhang, Mackensie R. Gross, Kyu Y. Rhee, Choukri Ben Mamoun, Björn F. C. Kafsack, Kirk W. Deitsch
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The primary antigenic and virulence determinant of the human malaria parasite Plasmodium falciparum is a variant surface protein called PfEMP1. Different forms of PfEMP1 are encoded by a multicopy gene family called var , and switching between active