Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kyu Jun Lee"'
Autor:
Jeong Hyeon Lee, Hye-Kyung Oh, Beom Seok Choi, Ho Hyeon Lee, Kyu Jun Lee, Un Gi Kim, Jina Lee, Hyerim Lee, Geon Seong Lee, Se Jun Ahn, Jeong Pil Han, Seokjoong Kim, Su Cheong Yeom, Dong Woo Song
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 551-562 (2022)
Recently, clinical trials of adeno-associated virus-mediated replacement therapy have suggested long-term therapeutic effects for several genetic diseases of the liver, including hemophilia. However, there remain concerns regarding decreased therapeu
Externí odkaz:
https://doaj.org/article/6ce05ab8d5ed4e9389d35cc55017b674
Autor:
Eunji Kim, Taeyoung Koo, Sung Wook Park, Daesik Kim, Kyoungmi Kim, Hee-Yeon Cho, Dong Woo Song, Kyu Jun Lee, Min Hee Jung, Seokjoong Kim, Jin Hyoung Kim, Jeong Hun Kim, Jin-Soo Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The amount of genetic material that can be packaged in AAV vectors used for genome editing is limited. Here the authors show that the smallest known Cas9 orthologue, cjCas9, can be packaged in a single AAV vector along with sgRNA and a marker gene, a
Externí odkaz:
https://doaj.org/article/979620e5b6d94aa09d84d0a42e5ed2a6
Autor:
Youn-Jeong Lee, Hyun-Mi Kang, Eun-Kyoung Lee, Byung-Min Song, Jipseol Jeong, Yong-Kuk Kwon, Hye-Ryoung Kim, Kyu-Jun Lee, Mi-Seon Hong, Il Jang, Kang-Seuk Choi, Ji-Ye Kim, Hyun-Jeong Lee, Min-Su Kang, Ok-Mi Jeong, Jong-Ho Baek, Yi-Seok Joo, Yong Ho Park, Hee-Soo Lee
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 6, Pp 1086-1089 (2014)
Externí odkaz:
https://doaj.org/article/23b43f27fab4454b99e2a0191624314e
Autor:
Jeong Pil Han, MinJeong Kim, Beom Seok Choi, Jeong Hyeon Lee, Geon Seong Lee, Michaela Jeong, Yeji Lee, Eun-Ah Kim, Hye-Kyung Oh, Nanyeong Go, Hyerim Lee, Kyu Jun Lee, Un Gi Kim, Jae Young Lee, Seokjoong Kim, Jun Chang, Hyukjin Lee, Dong Woo Song, Su Cheong Yeom
Publikováno v:
Science Advances
Hemophilia is a hereditary disease that remains incurable. Although innovative treatments such as gene therapy or bispecific antibody therapy have been introduced, substantial unmet needs still exist with respect to achieving long-lasting therapeutic
Autor:
Hyun-Mi Kang, Ha-Young Park, Kyu-Jun Lee, Jun-Gu Choi, Eun-Kyoung Lee, Byung-Min Song, Hee-Soo Lee, Youn-Jeong Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e91887 (2014)
During surveillance programs in Korea between January 2006 and March 2011, 31 H7 avian influenza viruses were isolated from wild birds and domestic ducks and genetically characterized using large-scale sequence data. All Korean H7 viruses belonged to
Externí odkaz:
https://doaj.org/article/8d08f75626864c19a7844a1cdd014231
Autor:
Hyejung Shin, Ok Jae Koo, Hohyeon Lee, Sangwoo Ham, Jungmin Lee, Kyeong-Min Kim, Hee Sook Bae, Kyu Jun Lee, Hee Kyoung Kim, Goo Jang, Jae Young Lee, Yun-Kyeong Jin, Gyu-bon Cho
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Thyroid hormone (TH) has long been believed to play a minor role in male reproduction. However, evidences from experimental model of thyrotoxicosis or hypothyroidism suggests its role in spermatogenesis. Cellular action of TH requires membrane transp
Autor:
Jin-Soo Kim, Dong Woo Song, Daesik Kim, Chang Sik Cho, Seokjoong Kim, Jin Hyoung Kim, Sung Wook Park, Jeong Hun Kim, Kyu Jun Lee, Dong Hyun Jo, Un Gi Kim, Kihwang Lee, Jungmin Lee
Publikováno v:
Science Advances
Therapeutic genome editing of a nonsense mutation showed functional gain in a mouse model of inherited retinal degeneration.
Leber congenital amaurosis (LCA), one of the leading causes of childhood-onset blindness, is caused by autosomal recessi
Leber congenital amaurosis (LCA), one of the leading causes of childhood-onset blindness, is caused by autosomal recessi
Autor:
Gyu-bon Cho, Jae Young Lee, Jungmin Lee, Goo Jang, Hyejung Shin, Yun-Kyeong Jin, Kyeong-Min Kim, Hohyeon Lee, Sangwoo Ham, Hee Sook Bae, Ok Jae Koo, Hee Kyoung Kim, Kyu Jun Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Hyun-Mi Kang, Hye-Ryoung Kim, Hyun-Jeong Lee, Byung-Min Song, Yong Ho Park, Hee-Soo Lee, Youn-Jeong Lee, Yi-Seok Joo, Min-Su Kang, Kyu-Jun Lee, Ji-Ye Kim, Eun Kyoung Lee, Kang-Seuk Choi, Yong-Kuk Kwon, Mi-Seon Hong, Jipseol Jeong, Jong-Ho Baek, Ok-Mi Jeong, Il Jang
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 20, Iss 6, Pp 1086-1089 (2014)
Emerging Infectious Diseases, Vol 20, Iss 6, Pp 1086-1089 (2014)
To the Editor: Highly pathogenic avian influenza (HPAI) viruses have caused considerable economic losses to the poultry industry and poses potential threats to animal and human health (www.oie.int/en/ and www.who.int/en/). Since 2003, influenza A(H5N
Autor:
Jun-Hun Kwon, Choi-Kyu Park, Jun-Gu Choi, Kwang-Il Kim, Min-Chul Kim, Youn-Jeong Lee, Jae-Hong Kim, Hyun-Mi Kang, Kyu-Jun Lee
Publikováno v:
Veterinary Microbiology. 162:623-630
Since 2003, the highly pathogenic avian influenza (HPAI) H5N1 has become a serious problem in animals and an increasing threat to public health. To develop effective vaccines for H5 HPAI in chickens, virus-like particles (VLP) were produced using a b