Zobrazeno 1 - 10
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pro vyhledávání: '"Kyro A"'
The link between in vitro hERG ion channel inhibition and subsequent in vivo QT interval prolongation, a critical risk factor for the development of arrythmias such as Torsade de Pointes, is so well established that in vitro hERG activity alone is of
Externí odkaz:
http://arxiv.org/abs/2403.07632
The incredible capabilities of generative artificial intelligence models have inevitably led to their application in the domain of drug discovery. Within this domain, the vastness of chemical space motivates the development of more efficient methods
Externí odkaz:
http://arxiv.org/abs/2309.05853
As the rapidly evolving field of machine learning continues to produce incredibly useful tools and models, the potential for quantum computing to provide speed up for machine learning algorithms is becoming increasingly desirable. In particular, quan
Externí odkaz:
http://arxiv.org/abs/2305.18961
Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon these advanc
Externí odkaz:
http://arxiv.org/abs/2212.12440
Autor:
Federica Maschietto, Uriel N. Morzan, Florentina Tofoleanu, Aria Gheeraert, Apala Chaudhuri, Gregory W. Kyro, Peter Nekrasov, Bernard Brooks, J. Patrick Loria, Ivan Rivalta, Victor S. Batista
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Allosteric drugs have the potential to revolutionize biomedicine due to their enhanced selectivity and protection against overdosage. However, we need to better understand allosteric mechanisms in order to fully harness their potential in dr
Externí odkaz:
https://doaj.org/article/c96d714daf7444efb6b389b4fdae9c83
Autor:
Andersen, Julie Louise Munk, Frederiksen, Kirsten, Kyrø, Cecilie, Hansen, Johnni, Raaschou-Nielsen, Ole, Overvad, Kim, Tjønneland, Anne, Olsen, Anja
Publikováno v:
In Diabetes Research and Clinical Practice November 2023 205
Autor:
Parmenter, Benjamin H., Pokharel, Pratik, Dalgaard, Frederik, Murray, Kevin, Cassidy, Aedín, Bondonno, Catherine P., Lewis, Joshua R., Kyrø, Cecilie, Tjønneland, Anne, Overvad, Kim, Hodgson, Jonathan M., Bondonno, Nicola P.
Publikováno v:
In The Journal of Nutrition November 2023 153(11):3280-3286
Autor:
Chen, Emily, Widjaja, Vinnie, Kyro, Gregory, Allen, Brandon, Das, Pragnya, Prahaladan, Varsha M., Bhandari, Vineet, Lolis, Elias J., Batista, Victor S., Lisi, George P.
Publikováno v:
In Journal of Biological Chemistry June 2023 299(6)
Autor:
Meyer, Antoine, Dong, Catherine, Casagrande, Corinne, Chan, Simon S.M., Huybrechts, Inge, Nicolas, Geneviève, Rauber, Fernanda, Levy, Renata Bertazzi, Millett, Christopher, Oldenburg, Bas, Weiderpass, Elisabete, Heath, Alicia K., Tong, Tammy Y.N., Tjønneland, Anne, Kyrø, Cecilie, Kaaks, Rudolf, Katzke, Verena A., Bergman, Manuela M., Palli, Domenico, Masala, Giovanna, Tumino, Rosario, Sacerdote, Carlotta, Colorado-Yohar, Sandra M., Sánchez, Maria-Jose, Grip, Olof, Lindgren, Stefan, Luben, Robert, Gunter, Marc J., Mahamat-Saleh, Yahya, Boutron-Ruault, Marie-Christine, Carbonnel, Franck
Publikováno v:
In Clinical Gastroenterology and Hepatology June 2023 21(6):1607-1616
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